8VYVC

Cryo-em structure of the braf k601e monomer
Total Genus 38
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
372
structure length
176
Chain Sequence
RSSITVGQRIGTVYKGKWHGDVAVKMQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKISILWMAYSFQSDVYAFGIVLYELMTGQCPKAMKRLMAECLRPLFPQILASIELLEPSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title BRAF oncogenic mutants evade autoinhibition through a common mechanism.
pubmed doi rcsb
molecule keywords 14-3-3 protein zeta/delta
molecule tags Transferase/inhibitor
source organism Homo sapiens
total genus 38
structure length 176
sequence length 372
ec nomenclature ec 2.7.11.1: non-specific serine/threonine protein kinase.
pdb deposition date 2024-02-09
Image from the rcsb pdb (www.rcsb.org)
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...