8W0WH

Crystal structure of broadly neutralizing antibody hcab64 in complex with hepatitis c virus envelope glycoprotein e2 ectodomain
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
227
structure length
224
Chain Sequence
QVQLVQSGAEIQKPGASVKVSCRASGYTYISTSFHWVRQAPGQGLEWMGVIKTDDGSTSDTQKFQGRLRMTWDTSTSTVYMELSSLRSDDTAVYYCVSPRLGHCRRGRCYETLDWGQGSLVTVSSASTKGPSVFPLAPSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Convergent evolution and targeting of diverse E2 epitopes by human bNAbs associated with HCV clearance
rcsb
molecule keywords Envelope glycoprotein E2
molecule tags Immune system/viral protein
source organism Hepacivirus hominis
total genus 37
structure length 224
sequence length 227
ec nomenclature
pdb deposition date 2024-02-14
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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