9E6KC

Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of adam17 on cancer cells.
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
115
structure length
115
Chain Sequence
AQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Fully human monoclonal antibody targeting the cysteine-rich substrate-interacting region of ADAM17 on cancer cells.
pubmed doi rcsb
molecule keywords heavy chain of monoclonal antibody C12
molecule tags Antitumor protein/immune system
source organism Homo sapiens
total genus 12
structure length 115
sequence length 115
ec nomenclature ec 3.4.24.86: ADAM 17 endopeptidase.
pdb deposition date 2024-10-30
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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