9FN8A

Crystal structure of human carboanhydrase xii with 4-benzyl-5,7,8-trifluoro-3,4-dihydro-2h-benzo[b][1,4]thiazine-6-sulfonamide 1,1-dioxide
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
259
structure length
259
Chain Sequence
WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design of Rigid Compounds to Enhance Selectivity for Carbonic Anhydrase IX.
pubmed doi rcsb
molecule keywords Carbonic anhydrase 12
molecule tags Lyase
source organism Homo sapiens
total genus 69
structure length 259
sequence length 259
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.1: carbonic anhydrase.
pdb deposition date 2024-06-09
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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