9KFUA

Human fgfr3 in complex with inhibitor f1
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
309
structure length
288
Chain Sequence
GPTLANVSELELPADPKWELSRARLTLGKPLGEGAFGQVVMAEAIGIDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPQQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVNTTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Electron-density-informed effective and reliable de novo molecular design and optimization with ED2Mol
doi rcsb
molecule keywords Fibroblast growth factor receptor 3
molecule tags Transferase
source organism Homo sapiens
total genus 93
structure length 288
sequence length 309
ec nomenclature ec 2.7.10.1: receptor protein-tyrosine kinase.
pdb deposition date 2024-11-07
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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