9OX9A

Cryo-em structure of s. mansoni p97 bound to cb-5083
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
566
structure length
539
Chain Sequence
EKLNEIGYDDIGGCRKQLAQIKEMVELPLRHPQLFKAIGVKPPRGILLYGPPGTGKTLVARAVANESGSFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRSHVIVMAATNRPNSVDPALRRFGRFDREIEIGIPDSIGRLEILRIHTRNIRLAEDVELEKIANEAHGHVGADLASLCSEAALQQIRNKMNLIIDAEVLNSLAVTMDDFRWALGKSNPSALRETTVEVPNVTWDDIGGLENVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGANVRDIFDKARQAAPCVLFFDELDSIAKAAADRVINQLLTEMDGMSAKKNVFIIGATNRPDIIDGAILRPGRLDQLIYIPLPDEASRVNILKANLRKSPIARDVDINFLAKATQGFSGADLTEICQRACKQAIRESIEAEIRAESEKKDFDPVPEITRRHFEEAMRFARRSVTENDVRKYEMFAQTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A genome-scale drug discovery pipeline uncovers therapeutic targets and a unique p97 allosteric binding site in Schistosoma mansoni.
pubmed doi rcsb
molecule keywords vesicle-fusing ATPase
molecule tags Chaperone
source organism Schistosoma mansoni
total genus 148
structure length 539
sequence length 566
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.6.4.6: vesicle-fusing ATPase.
pdb deposition date 2025-06-03
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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