1A5LA

K217c variant of klebsiella aerogenes urease
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
100
structure length
100
Chain Sequence
MELTPREKDKLLLFTAALVAERRLARGLKLNYPESVALISAFIMEGARDGKSVASLMEEGRHVLTREQVMEGVPEMIPDIQVEATFPDGSKLVTVHNPII
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords UREASE (GAMMA SUBUNIT)
publication title Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand.
pubmed doi rcsb
source organism Klebsiella aerogenes
total genus 28
structure length 100
sequence length 100
ec nomenclature ec 3.5.1.5: Urease.
pdb deposition date 1998-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00547 Urease_gamma Urease, gamma subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.280.10 Alpha Beta 2-Layer Sandwich Urease; subunit A Urease, gamma-like subunit 1a5lA00
1A5LA 4G7EA 4EPDA 1EJUA 4CEUA 1FWEA 4G7EB 1A5OA 1EF2C 3UBPA 1FWGA 4GOAA 4UBPA 4AC7A 4H9MA 1IE7A 4GY7A 1EJXA 5A6TA 1FWFA 1FWDA 1A5MA 1EJRA 1A5NA 1FWAA 3QGKA 1KRCA 4Z42A 1FWCA 1FWHA 1EJWA 1FWBA 2FVHA 4EP8A 1EJSA 1A5KA 1EJVA 1EJTA 1KRBA 2KAUA 1UBPA 1E9ZA 2UBPA 4CEXA 1FWIA 1FWJA 1KRAA 1S3TA 5G4HA 4EPBA 3QGAA 5FSEA 4FURA 1E9YA 3LA4A 4EPEA 5FSDA
chains in the Genus database with same CATH superfamily
1A5LA 4G7EA 4EPDA 1EJUA 4CEUA 1FWEA 4G7EB 1A5OA 1EF2C 3UBPA 1FWGA 4GOAA 4UBPA 4AC7A 4H9MA 1IE7A 4GY7A 1EJXA 5A6TA 1FWFA 1FWDA 1A5MA 1EJRA 1A5NA 1FWAA 3QGKA 1KRCA 4Z42A 1FWCA 1FWHA 1EJWA 1FWBA 2FVHA 4EP8A 1EJSA 1A5KA 1EJVA 1EJTA 1KRBA 2KAUA 1UBPA 1E9ZA 2UBPA 4CEXA 1FWIA 1FWJA 1KRAA 1S3TA 5G4HA 4EPBA 3QGAA 5FSEA 4FURA 1E9YA 3LA4A 4EPEA 5FSDA
chains in the Genus database with same CATH topology
1A5LA 4G7EA 4EPDA 1EJUA 4CEUA 1FWEA 4G7EB 1A5OA 1EF2C 3UBPA 1FWGA 4GOAA 4UBPA 4AC7A 4H9MA 1IE7A 4GY7A 1EJXA 5A6TA 1FWFA 1FWDA 1A5MA 1EJRA 1A5NA 1FWAA 3QGKA 1KRCA 4Z42A 1FWCA 1FWHA 1EJWA 1FWBA 2FVHA 4EP8A 1EJSA 1A5KA 1EJVA 1EJTA 1KRBA 2KAUA 1UBPA 1E9ZA 2UBPA 4CEXA 1FWIA 1FWJA 1KRAA 1S3TA 5G4HA 4EPBA 3QGAA 5FSEA 4FURA 1E9YA 3LA4A 4EPEA 5FSDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A5L A;  4G7E A;  4EPD A;  1EJU A;  4CEU A;  1FWE A;  4G7E B;  1A5O A;  1EF2 C;  3UBP A;  1FWG A;  4GOA A;  4UBP A;  4AC7 A;  4H9M A;  1IE7 A;  4GY7 A;  1EJX A;  5A6T A;  1FWF A;  1FWD A;  1A5M A;  1EJR A;  1A5N A;  1FWA A;  3QGK A;  1KRC A;  4Z42 A;  1FWC A;  1FWH A;  1EJW A;  1FWB A;  2FVH A;  4EP8 A;  1EJS A;  1A5K A;  1EJV A;  1EJT A;  1KRB A;  2KAU A;  1UBP A;  1E9Z A;  2UBP A;  4CEX A;  1FWI A;  1FWJ A;  1KRA A;  1S3T A;  5G4H A;  4EPB A;  3QGA A;  5FSE A;  4FUR A;  1E9Y A;  3LA4 A;  4EPE A;  5FSD A; 
#chains in the Genus database with same CATH topology
 1A5L A;  4G7E A;  4EPD A;  1EJU A;  4CEU A;  1FWE A;  4G7E B;  1A5O A;  1EF2 C;  3UBP A;  1FWG A;  4GOA A;  4UBP A;  4AC7 A;  4H9M A;  1IE7 A;  4GY7 A;  1EJX A;  5A6T A;  1FWF A;  1FWD A;  1A5M A;  1EJR A;  1A5N A;  1FWA A;  3QGK A;  1KRC A;  4Z42 A;  1FWC A;  1FWH A;  1EJW A;  1FWB A;  2FVH A;  4EP8 A;  1EJS A;  1A5K A;  1EJV A;  1EJT A;  1KRB A;  2KAU A;  1UBP A;  1E9Z A;  2UBP A;  4CEX A;  1FWI A;  1FWJ A;  1KRA A;  1S3T A;  5G4H A;  4EPB A;  3QGA A;  5FSE A;  4FUR A;  1E9Y A;  3LA4 A;  4EPE A;  5FSD A; 
#chains in the Genus database with same CATH homology
 1A5L A;  4G7E A;  4EPD A;  1EJU A;  4CEU A;  1FWE A;  4G7E B;  1A5O A;  1EF2 C;  3UBP A;  1FWG A;  4GOA A;  4UBP A;  4AC7 A;  4H9M A;  1IE7 A;  4GY7 A;  1EJX A;  5A6T A;  1FWF A;  1FWD A;  1A5M A;  1EJR A;  1A5N A;  1FWA A;  3QGK A;  1KRC A;  4Z42 A;  1FWC A;  1FWH A;  1EJW A;  1FWB A;  2FVH A;  4EP8 A;  1EJS A;  1A5K A;  1EJV A;  1EJT A;  1KRB A;  2KAU A;  1UBP A;  1E9Z A;  2UBP A;  4CEX A;  1FWI A;  1FWJ A;  1KRA A;  1S3T A;  5G4H A;  4EPB A;  3QGA A;  5FSE A;  4FUR A;  1E9Y A;  3LA4 A;  4EPE A;  5FSD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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