1HPJA

Solution nmr structure of the human plasminogen kringle 1 domain complexed with 6-aminohexanoic acid at ph 5.3, 310k, derived from randomly generated structures using simulated annealing, 12 structures
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
79
structure length
79
Chain Sequence
CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Serine protease
molecule keywords PLASMINOGEN
publication title Solution structure of the epsilon-aminohexanoic acid complex of human plasminogen kringle 1.
pubmed doi rcsb
total genus 10
structure length 79
sequence length 79
ec nomenclature ec 3.4.21.7: Plasmin.
pdb deposition date 1996-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00051 Kringle Kringle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 1hpjA00
1PK2A 5CT1A 3U73A 1JFNA 1PKRA 2HPPP 3BT1A 3LAQA 1KIVA 3KIVA 3E6PL 4BVDA 4D3CA 2FEBA 4BV7A 4A5TS 4KIVA 3K65A 4BVWA 1NK1A 4DURA 1B2IA 1PMKA 2KJ4A 3BT2A 2PF2A 1HPJA 5CS3A 1PMLA 1URKA 1HPKA 5CT2A 5CT3A 1GMNA 1CEBA 2DOHX 3NXPA 1KDUA 2DOIA 2K51A 1PK4A 2I9AA 1TPKA 3MKPA 2KNFA 4IUAA 2HPQP 1NL2A 1BHTA 2K4RA 4NZQA 1NL1A 2I9BA 1GP9A 5CS1A 4O03A 1A0HA 3HN4A 4BVVA 4BVCA 5CS5A 2QJ4A 2FD6A 4CIKA 2PF1A 5HPGA 2PK4A 4HZHA 2QJ2A 2L0SA 1KI0A 5CS9A 4BV5A 5CP9A 3SP8A 2SPTA 1I5KA 1I71A 1GMOA 1KRNA 5COEA 5CSQA 1CEAA
chains in the Genus database with same CATH superfamily
1PK2A 5CT1A 3U73A 1JFNA 1PKRA 2HPPP 3BT1A 3LAQA 1KIVA 3KIVA 3E6PL 4BVDA 4D3CA 2FEBA 4BV7A 4A5TS 4KIVA 3K65A 4BVWA 1NK1A 4DURA 1B2IA 1PMKA 2KJ4A 3BT2A 2PF2A 1HPJA 5CS3A 1PMLA 1URKA 1HPKA 5CT2A 5CT3A 1GMNA 1CEBA 2DOHX 3NXPA 1KDUA 2DOIA 2K51A 1PK4A 2I9AA 1TPKA 3MKPA 2KNFA 4IUAA 2HPQP 1NL2A 1BHTA 2K4RA 4NZQA 1NL1A 2I9BA 1GP9A 5CS1A 4O03A 1A0HA 3HN4A 4BVVA 4BVCA 5CS5A 2QJ4A 2FD6A 4CIKA 2PF1A 5HPGA 2PK4A 4HZHA 2QJ2A 2L0SA 1KI0A 5CS9A 4BV5A 5CP9A 3SP8A 2SPTA 1I5KA 1I71A 1GMOA 1KRNA 5COEA 5CSQA 1CEAA
chains in the Genus database with same CATH topology
1PK2A 5CT1A 3U73A 1JFNA 1PKRA 2HPPP 3BT1A 3LAQA 1KIVA 3KIVA 3E6PL 4BVDA 4D3CA 2FEBA 4BV7A 4A5TS 4KIVA 3K65A 4BVWA 1NK1A 4DURA 1B2IA 1PMKA 2KJ4A 3BT2A 2PF2A 1HPJA 5CS3A 1PMLA 1URKA 1HPKA 5CT2A 5CT3A 1GMNA 1CEBA 2DOHX 3NXPA 1KDUA 2DOIA 2K51A 1PK4A 2I9AA 1TPKA 3MKPA 2KNFA 4IUAA 2HPQP 1NL2A 1BHTA 2K4RA 4NZQA 1NL1A 2I9BA 1GP9A 5CS1A 4O03A 1A0HA 3HN4A 4BVVA 4BVCA 5CS5A 2QJ4A 2FD6A 4CIKA 2PF1A 5HPGA 2PK4A 4HZHA 2QJ2A 2L0SA 1KI0A 5CS9A 4BV5A 5CP9A 3SP8A 2SPTA 1I5KA 1I71A 1GMOA 1KRNA 5COEA 5CSQA 1CEAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PK2 A;  5CT1 A;  3U73 A;  1JFN A;  1PKR A;  2HPP P;  3BT1 A;  3LAQ A;  1KIV A;  3KIV A;  3E6P L;  4BVD A;  4D3C A;  2FEB A;  4BV7 A;  4A5T S;  4KIV A;  3K65 A;  4BVW A;  1NK1 A;  4DUR A;  1B2I A;  1PMK A;  2KJ4 A;  3BT2 A;  2PF2 A;  1HPJ A;  5CS3 A;  1PML A;  1URK A;  1HPK A;  5CT2 A;  5CT3 A;  1GMN A;  1CEB A;  2DOH X;  3NXP A;  1KDU A;  2DOI A;  2K51 A;  1PK4 A;  2I9A A;  1TPK A;  3MKP A;  2KNF A;  4IUA A;  2HPQ P;  1NL2 A;  1BHT A;  2K4R A;  4NZQ A;  1NL1 A;  2I9B A;  1GP9 A;  5CS1 A;  4O03 A;  1A0H A;  3HN4 A;  4BVV A;  4BVC A;  5CS5 A;  2QJ4 A;  2FD6 A;  4CIK A;  2PF1 A;  5HPG A;  2PK4 A;  4HZH A;  2QJ2 A;  2L0S A;  1KI0 A;  5CS9 A;  4BV5 A;  5CP9 A;  3SP8 A;  2SPT A;  1I5K A;  1I71 A;  1GMO A;  1KRN A;  5COE A;  5CSQ A;  1CEA A; 
#chains in the Genus database with same CATH topology
 1PK2 A;  5CT1 A;  3U73 A;  1JFN A;  1PKR A;  2HPP P;  3BT1 A;  3LAQ A;  1KIV A;  3KIV A;  3E6P L;  4BVD A;  4D3C A;  2FEB A;  4BV7 A;  4A5T S;  4KIV A;  3K65 A;  4BVW A;  1NK1 A;  4DUR A;  1B2I A;  1PMK A;  2KJ4 A;  3BT2 A;  2PF2 A;  1HPJ A;  5CS3 A;  1PML A;  1URK A;  1HPK A;  5CT2 A;  5CT3 A;  1GMN A;  1CEB A;  2DOH X;  3NXP A;  1KDU A;  2DOI A;  2K51 A;  1PK4 A;  2I9A A;  1TPK A;  3MKP A;  2KNF A;  4IUA A;  2HPQ P;  1NL2 A;  1BHT A;  2K4R A;  4NZQ A;  1NL1 A;  2I9B A;  1GP9 A;  5CS1 A;  4O03 A;  1A0H A;  3HN4 A;  4BVV A;  4BVC A;  5CS5 A;  2QJ4 A;  2FD6 A;  4CIK A;  2PF1 A;  5HPG A;  2PK4 A;  4HZH A;  2QJ2 A;  2L0S A;  1KI0 A;  5CS9 A;  4BV5 A;  5CP9 A;  3SP8 A;  2SPT A;  1I5K A;  1I71 A;  1GMO A;  1KRN A;  5COE A;  5CSQ A;  1CEA A; 
#chains in the Genus database with same CATH homology
 1PK2 A;  5CT1 A;  3U73 A;  1JFN A;  1PKR A;  2HPP P;  3BT1 A;  3LAQ A;  1KIV A;  3KIV A;  3E6P L;  4BVD A;  4D3C A;  2FEB A;  4BV7 A;  4A5T S;  4KIV A;  3K65 A;  4BVW A;  1NK1 A;  4DUR A;  1B2I A;  1PMK A;  2KJ4 A;  3BT2 A;  2PF2 A;  1HPJ A;  5CS3 A;  1PML A;  1URK A;  1HPK A;  5CT2 A;  5CT3 A;  1GMN A;  1CEB A;  2DOH X;  3NXP A;  1KDU A;  2DOI A;  2K51 A;  1PK4 A;  2I9A A;  1TPK A;  3MKP A;  2KNF A;  4IUA A;  2HPQ P;  1NL2 A;  1BHT A;  2K4R A;  4NZQ A;  1NL1 A;  2I9B A;  1GP9 A;  5CS1 A;  4O03 A;  1A0H A;  3HN4 A;  4BVV A;  4BVC A;  5CS5 A;  2QJ4 A;  2FD6 A;  4CIK A;  2PF1 A;  5HPG A;  2PK4 A;  4HZH A;  2QJ2 A;  2L0S A;  1KI0 A;  5CS9 A;  4BV5 A;  5CP9 A;  3SP8 A;  2SPT A;  1I5K A;  1I71 A;  1GMO A;  1KRN A;  5COE A;  5CSQ A;  1CEA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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