3E6PL

Crystal structure of human meizothrombin desf1
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
150
structure length
150
Chain Sequence
QCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Prothrombin
publication title Na(+) binding to meizothrombin desF1.
pubmed doi rcsb
source organism Homo sapiens
total genus 19
structure length 150
sequence length 150
ec nomenclature ec 3.4.21.5: Thrombin.
pdb deposition date 2008-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF00051 Kringle Kringle domain
L PF09396 Thrombin_light Thrombin light chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.20.10 Mainly Beta Beta Barrel Plasminogen Kringle 4 Plasminogen Kringle 4 3e6pL01
4.10.140.10 Few Secondary Structures Irregular Epsilon-Thrombin; Chain L Thrombin light chain domain 3e6pL02
3HKIA 2L0SA 4NZQA 4HZHA 4BV7A 1HPJA 2FD6A 4BVVA 2PF1A 2KJ4A 1GMNA 2DOIA 4BVDA 2HPQP 5COEA 5CSQA 1JFNA 4DY7A 2K4RA 4BVWA 2QJ2A 5HPGA 3LU9A 4RKOA 1TQ7A 3BT2A 1NK1A 5CT2A 1GP9A 5CS3A 1KDUA 4DURA 2PUXA 1I5KA 2QJ4A 3NXPA 1BHTA 2PGQA 2PV9A 4IUAA 4CIKA 5CP9A 4A5TS 3E6PL 1HPKA 2K51A 1TBQJ 1A0HA 1NL1A 3B9FL 1JOUA 1URKA 5CS1A 5CT1A 5CT3A 1Z8JA 1KIVA 2FEBA 1PK2A 1PKRA 1KI0A 3K65A 1JMOL 5CS5A 1I71A 1PMLA 2SPTA 2DOHX 4O03A 3HK6A 3U73A 2HPPP 3SP8A 4D3CA 4BVCA 2B5TA 3BEIA 1B2IA 1KRNA 2PF2A 3LAQA 4KIVA 3BEFA 1GMOA 2I9AA 3HN4A 3GISA 1PMKA 3BT1A 1CEAA 3MKPA 3EDXA 2ODYA 1TBRJ 5CS9A 1TPKA 1CEBA 1NL2A 4BV5A 1TB6L 1AVGL 2I9BA 2A1DA 2KNFA 1PK4A 3KIVA 2PK4A
chains in the Genus database with same CATH superfamily
3HKIA 2L0SA 4NZQA 4HZHA 4BV7A 1HPJA 2FD6A 4BVVA 2PF1A 2KJ4A 1GMNA 2DOIA 4BVDA 2HPQP 5COEA 5CSQA 1JFNA 4DY7A 2K4RA 4BVWA 2QJ2A 5HPGA 3LU9A 4RKOA 1TQ7A 3BT2A 1NK1A 5CT2A 1GP9A 5CS3A 1KDUA 4DURA 2PUXA 1I5KA 2QJ4A 3NXPA 1BHTA 2PGQA 2PV9A 4IUAA 4CIKA 5CP9A 4A5TS 3E6PL 1HPKA 2K51A 1TBQJ 1A0HA 1NL1A 3B9FL 1JOUA 1URKA 5CS1A 5CT1A 5CT3A 1Z8JA 1KIVA 2FEBA 1PK2A 1PKRA 1KI0A 3K65A 1JMOL 5CS5A 1I71A 1PMLA 2SPTA 2DOHX 4O03A 3HK6A 3U73A 2HPPP 3SP8A 4D3CA 4BVCA 2B5TA 3BEIA 1B2IA 1KRNA 2PF2A 3LAQA 4KIVA 3BEFA 1GMOA 2I9AA 3HN4A 3GISA 1PMKA 3BT1A 1CEAA 3MKPA 3EDXA 2ODYA 1TBRJ 5CS9A 1TPKA 1CEBA 1NL2A 4BV5A 1TB6L 1AVGL 2I9BA 2A1DA 2KNFA 1PK4A 3KIVA 2PK4A
chains in the Genus database with same CATH topology
3HKIA 2L0SA 4NZQA 4HZHA 4BV7A 1HPJA 2FD6A 4BVVA 2PF1A 2KJ4A 1GMNA 2DOIA 4BVDA 2HPQP 5COEA 5CSQA 1JFNA 4DY7A 2K4RA 4BVWA 2QJ2A 5HPGA 3LU9A 4RKOA 1TQ7A 3BT2A 1NK1A 5CT2A 1GP9A 5CS3A 1KDUA 4DURA 2PUXA 1I5KA 2QJ4A 3NXPA 1BHTA 2PGQA 2PV9A 4IUAA 4CIKA 5CP9A 4A5TS 3E6PL 1HPKA 2K51A 1TBQJ 1A0HA 1NL1A 3B9FL 1JOUA 1URKA 5CS1A 5CT1A 5CT3A 1Z8JA 1KIVA 2FEBA 1PK2A 1PKRA 1KI0A 3K65A 1JMOL 5CS5A 1I71A 1PMLA 2SPTA 2DOHX 4O03A 3HK6A 3U73A 2HPPP 3SP8A 4D3CA 4BVCA 2B5TA 3BEIA 1B2IA 1KRNA 2PF2A 3LAQA 4KIVA 3BEFA 1GMOA 2I9AA 3HN4A 3GISA 1PMKA 3BT1A 1CEAA 3MKPA 3EDXA 2ODYA 1TBRJ 5CS9A 1TPKA 1CEBA 1NL2A 4BV5A 1TB6L 1AVGL 2I9BA 2A1DA 2KNFA 1PK4A 3KIVA 2PK4A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3HKI A;  2L0S A;  4NZQ A;  4HZH A;  4BV7 A;  1HPJ A;  2FD6 A;  4BVV A;  2PF1 A;  2KJ4 A;  1GMN A;  2DOI A;  4BVD A;  2HPQ P;  5COE A;  5CSQ A;  1JFN A;  4DY7 A;  2K4R A;  4BVW A;  2QJ2 A;  5HPG A;  3LU9 A;  4RKO A;  1TQ7 A;  3BT2 A;  1NK1 A;  5CT2 A;  1GP9 A;  5CS3 A;  1KDU A;  4DUR A;  2PUX A;  1I5K A;  2QJ4 A;  3NXP A;  1BHT A;  2PGQ A;  2PV9 A;  4IUA A;  4CIK A;  5CP9 A;  4A5T S;  3E6P L;  1HPK A;  2K51 A;  1TBQ J;  1A0H A;  1NL1 A;  3B9F L;  1JOU A;  1URK A;  5CS1 A;  5CT1 A;  5CT3 A;  1Z8J A;  1KIV A;  2FEB A;  1PK2 A;  1PKR A;  1KI0 A;  3K65 A;  1JMO L;  5CS5 A;  1I71 A;  1PML A;  2SPT A;  2DOH X;  4O03 A;  3HK6 A;  3U73 A;  2HPP P;  3SP8 A;  4D3C A;  4BVC A;  2B5T A;  3BEI A;  1B2I A;  1KRN A;  2PF2 A;  3LAQ A;  4KIV A;  3BEF A;  1GMO A;  2I9A A;  3HN4 A;  3GIS A;  1PMK A;  3BT1 A;  1CEA A;  3MKP A;  3EDX A;  2ODY A;  1TBR J;  5CS9 A;  1TPK A;  1CEB A;  1NL2 A;  4BV5 A;  1TB6 L;  1AVG L;  2I9B A;  2A1D A;  2KNF A;  1PK4 A;  3KIV A;  2PK4 A; 
#chains in the Genus database with same CATH topology
 3HKI A;  2L0S A;  4NZQ A;  4HZH A;  4BV7 A;  1HPJ A;  2FD6 A;  4BVV A;  2PF1 A;  2KJ4 A;  1GMN A;  2DOI A;  4BVD A;  2HPQ P;  5COE A;  5CSQ A;  1JFN A;  4DY7 A;  2K4R A;  4BVW A;  2QJ2 A;  5HPG A;  3LU9 A;  4RKO A;  1TQ7 A;  3BT2 A;  1NK1 A;  5CT2 A;  1GP9 A;  5CS3 A;  1KDU A;  4DUR A;  2PUX A;  1I5K A;  2QJ4 A;  3NXP A;  1BHT A;  2PGQ A;  2PV9 A;  4IUA A;  4CIK A;  5CP9 A;  4A5T S;  3E6P L;  1HPK A;  2K51 A;  1TBQ J;  1A0H A;  1NL1 A;  3B9F L;  1JOU A;  1URK A;  5CS1 A;  5CT1 A;  5CT3 A;  1Z8J A;  1KIV A;  2FEB A;  1PK2 A;  1PKR A;  1KI0 A;  3K65 A;  1JMO L;  5CS5 A;  1I71 A;  1PML A;  2SPT A;  2DOH X;  4O03 A;  3HK6 A;  3U73 A;  2HPP P;  3SP8 A;  4D3C A;  4BVC A;  2B5T A;  3BEI A;  1B2I A;  1KRN A;  2PF2 A;  3LAQ A;  4KIV A;  3BEF A;  1GMO A;  2I9A A;  3HN4 A;  3GIS A;  1PMK A;  3BT1 A;  1CEA A;  3MKP A;  3EDX A;  2ODY A;  1TBR J;  5CS9 A;  1TPK A;  1CEB A;  1NL2 A;  4BV5 A;  1TB6 L;  1AVG L;  2I9B A;  2A1D A;  2KNF A;  1PK4 A;  3KIV A;  2PK4 A; 
#chains in the Genus database with same CATH homology
 3HKI A;  2L0S A;  4NZQ A;  4HZH A;  4BV7 A;  1HPJ A;  2FD6 A;  4BVV A;  2PF1 A;  2KJ4 A;  1GMN A;  2DOI A;  4BVD A;  2HPQ P;  5COE A;  5CSQ A;  1JFN A;  4DY7 A;  2K4R A;  4BVW A;  2QJ2 A;  5HPG A;  3LU9 A;  4RKO A;  1TQ7 A;  3BT2 A;  1NK1 A;  5CT2 A;  1GP9 A;  5CS3 A;  1KDU A;  4DUR A;  2PUX A;  1I5K A;  2QJ4 A;  3NXP A;  1BHT A;  2PGQ A;  2PV9 A;  4IUA A;  4CIK A;  5CP9 A;  4A5T S;  3E6P L;  1HPK A;  2K51 A;  1TBQ J;  1A0H A;  1NL1 A;  3B9F L;  1JOU A;  1URK A;  5CS1 A;  5CT1 A;  5CT3 A;  1Z8J A;  1KIV A;  2FEB A;  1PK2 A;  1PKR A;  1KI0 A;  3K65 A;  1JMO L;  5CS5 A;  1I71 A;  1PML A;  2SPT A;  2DOH X;  4O03 A;  3HK6 A;  3U73 A;  2HPP P;  3SP8 A;  4D3C A;  4BVC A;  2B5T A;  3BEI A;  1B2I A;  1KRN A;  2PF2 A;  3LAQ A;  4KIV A;  3BEF A;  1GMO A;  2I9A A;  3HN4 A;  3GIS A;  1PMK A;  3BT1 A;  1CEA A;  3MKP A;  3EDX A;  2ODY A;  1TBR J;  5CS9 A;  1TPK A;  1CEB A;  1NL2 A;  4BV5 A;  1TB6 L;  1AVG L;  2I9B A;  2A1D A;  2KNF A;  1PK4 A;  3KIV A;  2PK4 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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