1S5EA

Cholera holotoxin, crystal form 1
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
236
structure length
232
Chain Sequence
NDDKLYRADSRPPDEIKQSGGLMPRGQSEYFDRGTQMNINLYDHARGTQGFVRHDDGYVSTSISLRSAHLVGQTILSGHSTYYIYVIATAPNMFNVNDVLGAYSPHPDEQEVSALGGIPYSQIYGWYRVHFGVLDEQLHRNRGYRDRYYSNLDIAPAADGYGLAGFPPEHRAWREEPWIHHAPPGCGNAPRSNTCDEKTQSLGVKFLDEYQSKVKRQIFSGYQSDIDTHNRI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase,toxin
molecule keywords Cholera enterotoxin, A chain precursor
publication title Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
pubmed doi rcsb
source organism Vibrio cholerae
total genus 67
structure length 232
sequence length 236
chains with identical sequence B
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 2004-01-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.210.10 Alpha Beta Alpha-Beta Complex Heat-Labile Enterotoxin; Chain A Heat-Labile Enterotoxin, subunit A 1s5eA00
1LTIA 1LTBA 1LTTA 1S5BA 2CB6A 1LTGA 2A5DB 1S5CA 1PRTA 1LT3A 2VSAA 2VSEA 1XTCA 1LTAA 1LT4A 1PTOA 1TIIA 1HTLA 4Z9CA 1LTSA 2A5FB 1BCPA 1S5DA 2A5GB 4K6LG 1S5FA 2CB4A 1S5EA
chains in the Genus database with same CATH superfamily
1LTIA 1LTBA 1LTTA 1S5BA 2CB6A 1LTGA 2A5DB 1S5CA 1PRTA 1LT3A 2VSAA 2VSEA 1XTCA 1LTAA 1LT4A 1PTOA 1TIIA 1HTLA 4Z9CA 1LTSA 2A5FB 1BCPA 1S5DA 2A5GB 4K6LG 1S5FA 2CB4A 1S5EA
chains in the Genus database with same CATH topology
1LTIA 1LTBA 1LTTA 1S5BA 2CB6A 1LTGA 2A5DB 1S5CA 1PRTA 1LT3A 2VSAA 2VSEA 1XTCA 1LTAA 1LT4A 1PTOA 1TIIA 1HTLA 4Z9CA 1LTSA 2A5FB 1BCPA 1S5DA 2A5GB 4K6LG 1S5FA 2CB4A 1S5EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LTI A;  1LTB A;  1LTT A;  1S5B A;  2CB6 A;  1LTG A;  2A5D B;  1S5C A;  1PRT A;  1LT3 A;  2VSA A;  2VSE A;  1XTC A;  1LTA A;  1LT4 A;  1PTO A;  1TII A;  1HTL A;  4Z9C A;  1LTS A;  2A5F B;  1BCP A;  1S5D A;  2A5G B;  4K6L G;  1S5F A;  2CB4 A;  1S5E A; 
#chains in the Genus database with same CATH topology
 1LTI A;  1LTB A;  1LTT A;  1S5B A;  2CB6 A;  1LTG A;  2A5D B;  1S5C A;  1PRT A;  1LT3 A;  2VSA A;  2VSE A;  1XTC A;  1LTA A;  1LT4 A;  1PTO A;  1TII A;  1HTL A;  4Z9C A;  1LTS A;  2A5F B;  1BCP A;  1S5D A;  2A5G B;  4K6L G;  1S5F A;  2CB4 A;  1S5E A; 
#chains in the Genus database with same CATH homology
 1LTI A;  1LTB A;  1LTT A;  1S5B A;  2CB6 A;  1LTG A;  2A5D B;  1S5C A;  1PRT A;  1LT3 A;  2VSA A;  2VSE A;  1XTC A;  1LTA A;  1LT4 A;  1PTO A;  1TII A;  1HTL A;  4Z9C A;  1LTS A;  2A5F B;  1BCP A;  1S5D A;  2A5G B;  4K6L G;  1S5F A;  2CB4 A;  1S5E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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