1TK7A

Nmr structure of ww domains (ww3-4) from suppressor of deltex
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
88
structure length
88
Chain Sequence
GSPEFHMDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQGQEVSLINEGPLPPGWEIRYTAAGERFFVDHNTRRTTFEDPRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Signaling protein
molecule keywords CG4244-PB
publication title The structure and dynamics of tandem WW domains in a negative regulator of notch signaling, Suppressor of deltex
pubmed doi rcsb
source organism Drosophila melanogaster
total genus 12
structure length 88
sequence length 88
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2004-06-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1tk7A01
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1tk7A02
1JMQA 3KADA 1YW5A 2M8JA 1TK7A 2YSIA 1K9RA 1O6WA 3KAFA 2RE3A 1EG4A 2JX8A 2ZQTA 4REXA 2DWVA 2E45A 1PINA 3KAGA 2XPBA 2YSGA 1WR7A 3NTPA 3TCZA 2ZQUA 2Q5AA 2ZAJA 2XP5A 2XP3A 3M7NA 3KCEA 2ZQSA 3KAIA 2ZR4A 4E5RA 2YSBA 2XP4A 2ZR5A 2M3OW 5AHTA 3TDBA 1NMVA 5CQ2A 4U85A 2LAJA 4QIBA 2ZR6A 4U86A 3M85A 2DK7A 2MDIA 1EG3A 3TC5A 1F8AB 2XP8A 2YSHA 2XP6A 2JV4A 2M8IA 2JXWA 3KAHA 3LE4A 1I5HW 3ODKA 2L4JA 1WMVA 2XPAA 2KXQA 2DJYA 3WH0A 3CNGA 1K9QA 2DMVA 2BA1A 2XP9A 3KABA 4U84A 2EZ5W 2DK1A 2ZQVA 2F21A 2JMFA 3L4HA 2XP7A 1ZCNA 2ITKA 3OOBA 2YSFA
chains in the Genus database with same CATH superfamily
1JMQA 3KADA 1YW5A 2M8JA 1TK7A 5E66A 2YSIA 3MCBB 1K9RA 5E5WA 1FLCA 1O6WA 1RP5A 3KAFA 2RE3A 1EG4A 4A0TA 2JX8A 2ZQTA 3LKXB 4REXA 2DWVA 2E45A 1PINA 3KAGA 2XPBA 2YSGA 1WR7A 3NTPA 3TCZA 3FS8A 2ZQUA 2Q5AA 2ZAJA 2XP5A 3PQHA 2XP3A 3M7NA 3FSBA 3KCEA 2ZQSA 3KAIA 2OWOA 2ZR4A 4E5RA 2YSBA 2XP4A 2ZR5A 2M3OW 2WADA 5AHTA 2QRVA 3TDBA 1NMVA 5CQ2A 4U85A 2LAJA 4QIBA 2ZR6A 4U86A 3M85A 2Y8NB 2DK7A 2MDIA 1EG3A 3TC5A 1F8AB 2XP8A 2YSHA 5E64A 2XP6A 3MQHA 2JV4A 2M8IA 3LKXA 2JXWA 3KAHA 3LE4A 1I5HW 2YAJB 5E62A 4GLXA 3ODKA 2L4JA 5U47A 2WAEA 3MQGA 1WMVA 2XPAA 2KXQA 2DJYA 3WH0A 3CNGA 3MCBA 1K9QA 2DMVA 2BA1A 2XP9A 3KABA 4U84A 5E65A 2EZ5W 2DK1A 2ZQVA 2F21A 2JMFA 3L4HA 4A0UA 2XP7A 1ZCNA 3FSCA 2ITKA 1TR8A 3OOBA 2YSFA
chains in the Genus database with same CATH topology
1JMQA 3KADA 1YW5A 2M8JA 1TK7A 5E66A 2YSIA 3MCBB 1K9RA 5E5WA 1FLCA 1O6WA 1RP5A 3KAFA 2RE3A 1EG4A 4A0TA 2JX8A 2ZQTA 3LKXB 4REXA 2DWVA 2E45A 1PINA 3KAGA 2XPBA 2YSGA 1WR7A 3NTPA 3TCZA 3FS8A 2ZQUA 2Q5AA 2ZAJA 2XP5A 3PQHA 2XP3A 3M7NA 3FSBA 3KCEA 2ZQSA 3KAIA 2OWOA 2ZR4A 4E5RA 2YSBA 2XP4A 2ZR5A 2M3OW 2WADA 5AHTA 2QRVA 3TDBA 1NMVA 5CQ2A 4U85A 2LAJA 4QIBA 2ZR6A 4U86A 3M85A 2Y8NB 2DK7A 2MDIA 1EG3A 3TC5A 1F8AB 2XP8A 2YSHA 5E64A 2XP6A 3MQHA 2JV4A 2M8IA 3LKXA 2JXWA 3KAHA 3LE4A 1I5HW 2YAJB 5E62A 4GLXA 3ODKA 2L4JA 5U47A 2WAEA 3MQGA 1WMVA 2XPAA 2KXQA 2DJYA 3WH0A 3CNGA 3MCBA 1K9QA 2DMVA 2BA1A 2XP9A 3KABA 4U84A 5E65A 2EZ5W 2DK1A 2ZQVA 2F21A 2JMFA 3L4HA 4A0UA 2XP7A 1ZCNA 3FSCA 2ITKA 1TR8A 3OOBA 2YSFA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1JMQ A;  3KAD A;  1YW5 A;  2M8J A;  1TK7 A;  2YSI A;  1K9R A;  1O6W A;  3KAF A;  2RE3 A;  1EG4 A;  2JX8 A;  2ZQT A;  4REX A;  2DWV A;  2E45 A;  1PIN A;  3KAG A;  2XPB A;  2YSG A;  1WR7 A;  3NTP A;  3TCZ A;  2ZQU A;  2Q5A A;  2ZAJ A;  2XP5 A;  2XP3 A;  3M7N A;  3KCE A;  2ZQS A;  3KAI A;  2ZR4 A;  4E5R A;  2YSB A;  2XP4 A;  2ZR5 A;  2M3O W;  5AHT A;  3TDB A;  1NMV A;  5CQ2 A;  4U85 A;  2LAJ A;  4QIB A;  2ZR6 A;  4U86 A;  3M85 A;  2DK7 A;  2MDI A;  1EG3 A;  3TC5 A;  1F8A B;  2XP8 A;  2YSH A;  2XP6 A;  2JV4 A;  2M8I A;  2JXW A;  3KAH A;  3LE4 A;  1I5H W;  3ODK A;  2L4J A;  1WMV A;  2XPA A;  2KXQ A;  2DJY A;  3WH0 A;  3CNG A;  1K9Q A;  2DMV A;  2BA1 A;  2XP9 A;  3KAB A;  4U84 A;  2EZ5 W;  2DK1 A;  2ZQV A;  2F21 A;  2JMF A;  3L4H A;  2XP7 A;  1ZCN A;  2ITK A;  3OOB A;  2YSF A; 
#chains in the Genus database with same CATH topology
 1JMQ A;  3KAD A;  1YW5 A;  2M8J A;  1TK7 A;  5E66 A;  2YSI A;  3MCB B;  1K9R A;  5E5W A;  1FLC A;  1O6W A;  1RP5 A;  3KAF A;  2RE3 A;  1EG4 A;  4A0T A;  2JX8 A;  2ZQT A;  3LKX B;  4REX A;  2DWV A;  2E45 A;  1PIN A;  3KAG A;  2XPB A;  2YSG A;  1WR7 A;  3NTP A;  3TCZ A;  3FS8 A;  2ZQU A;  2Q5A A;  2ZAJ A;  2XP5 A;  3PQH A;  2XP3 A;  3M7N A;  3FSB A;  3KCE A;  2ZQS A;  3KAI A;  2OWO A;  2ZR4 A;  4E5R A;  2YSB A;  2XP4 A;  2ZR5 A;  2M3O W;  2WAD A;  5AHT A;  2QRV A;  3TDB A;  1NMV A;  5CQ2 A;  4U85 A;  2LAJ A;  4QIB A;  2ZR6 A;  4U86 A;  3M85 A;  2Y8N B;  2DK7 A;  2MDI A;  1EG3 A;  3TC5 A;  1F8A B;  2XP8 A;  2YSH A;  5E64 A;  2XP6 A;  3MQH A;  2JV4 A;  2M8I A;  3LKX A;  2JXW A;  3KAH A;  3LE4 A;  1I5H W;  2YAJ B;  5E62 A;  4GLX A;  3ODK A;  2L4J A;  5U47 A;  2WAE A;  3MQG A;  1WMV A;  2XPA A;  2KXQ A;  2DJY A;  3WH0 A;  3CNG A;  3MCB A;  1K9Q A;  2DMV A;  2BA1 A;  2XP9 A;  3KAB A;  4U84 A;  5E65 A;  2EZ5 W;  2DK1 A;  2ZQV A;  2F21 A;  2JMF A;  3L4H A;  4A0U A;  2XP7 A;  1ZCN A;  3FSC A;  2ITK A;  1TR8 A;  3OOB A;  2YSF A; 
#chains in the Genus database with same CATH homology
 1JMQ A;  3KAD A;  1YW5 A;  2M8J A;  1TK7 A;  5E66 A;  2YSI A;  3MCB B;  1K9R A;  5E5W A;  1FLC A;  1O6W A;  1RP5 A;  3KAF A;  2RE3 A;  1EG4 A;  4A0T A;  2JX8 A;  2ZQT A;  3LKX B;  4REX A;  2DWV A;  2E45 A;  1PIN A;  3KAG A;  2XPB A;  2YSG A;  1WR7 A;  3NTP A;  3TCZ A;  3FS8 A;  2ZQU A;  2Q5A A;  2ZAJ A;  2XP5 A;  3PQH A;  2XP3 A;  3M7N A;  3FSB A;  3KCE A;  2ZQS A;  3KAI A;  2OWO A;  2ZR4 A;  4E5R A;  2YSB A;  2XP4 A;  2ZR5 A;  2M3O W;  2WAD A;  5AHT A;  2QRV A;  3TDB A;  1NMV A;  5CQ2 A;  4U85 A;  2LAJ A;  4QIB A;  2ZR6 A;  4U86 A;  3M85 A;  2Y8N B;  2DK7 A;  2MDI A;  1EG3 A;  3TC5 A;  1F8A B;  2XP8 A;  2YSH A;  5E64 A;  2XP6 A;  3MQH A;  2JV4 A;  2M8I A;  3LKX A;  2JXW A;  3KAH A;  3LE4 A;  1I5H W;  2YAJ B;  5E62 A;  4GLX A;  3ODK A;  2L4J A;  5U47 A;  2WAE A;  3MQG A;  1WMV A;  2XPA A;  2KXQ A;  2DJY A;  3WH0 A;  3CNG A;  3MCB A;  1K9Q A;  2DMV A;  2BA1 A;  2XP9 A;  3KAB A;  4U84 A;  5E65 A;  2EZ5 W;  2DK1 A;  2ZQV A;  2F21 A;  2JMF A;  3L4H A;  4A0U A;  2XP7 A;  1ZCN A;  3FSC A;  2ITK A;  1TR8 A;  3OOB A;  2YSF A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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