1WR7A

Solution structure of the third ww domain of nedd4-2
Total Genus 4
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
41
structure length
41
Chain Sequence
GSPGIQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Ligase
molecule keywords Nedd4-2
publication title Solution structures of the WW domains of Nedd4-2
rcsb
source organism Mus musculus
total genus 4
structure length 41
sequence length 41
ec nomenclature ec 2.3.2.26: HECT-type E3 ubiquitin transferase.
pdb deposition date 2004-10-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 1wr7A01
3OOBA 2ZQTA 3LE4A 3KCEA 2XP6A 5AHTA 2JXWA 1TK7A 1EG3A 2XP8A 1PINA 1O6WA 3NTPA 4U86A 2YSFA 2KXQA 1K9RA 1I5HW 2XP4A 2F21A 1F8AB 2JV4A 2YSBA 4REXA 3KAHA 3KABA 2MDIA 2XP5A 1EG4A 2M8IA 3KAIA 2ITKA 2JX8A 2YSHA 2RE3A 2ZQUA 2YSIA 2BA1A 2ZQVA 3ODKA 2Q5AA 2XP9A 4E5RA 1JMQA 3M7NA 3KAGA 2DK1A 2ZR6A 3TC5A 1K9QA 2YSGA 2ZR5A 2XP3A 3L4HA 2E45A 4U85A 3KAFA 3TDBA 2XPAA 1WMVA 4U84A 2XP7A 2L4JA 2EZ5W 2M3OW 2DMVA 2ZAJA 1ZCNA 3WH0A 2DWVA 3TCZA 1NMVA 3KADA 3CNGA 3M85A 2ZQSA 1YW5A 4QIBA 2M8JA 2JMFA 1WR7A 2DJYA 2XPBA 2DK7A 2LAJA 2ZR4A 5CQ2A
chains in the Genus database with same CATH superfamily
3OOBA 5E65A 2ZQTA 3FS8A 3LE4A 3KCEA 2XP6A 5AHTA 5E5WA 2JXWA 1TK7A 1EG3A 2XP8A 1TR8A 1PINA 1O6WA 3NTPA 4U86A 2YSFA 2KXQA 1K9RA 1I5HW 2WADA 2XP4A 4A0UA 2F21A 1F8AB 2JV4A 3MCBA 2YSBA 4REXA 3KAHA 3KABA 2MDIA 2WAEA 2XP5A 1EG4A 2M8IA 3KAIA 3MCBB 2OWOA 2QRVA 2ITKA 2JX8A 2YSHA 2RE3A 2Y8NB 2ZQUA 5E64A 2YSIA 2BA1A 2ZQVA 3FSCA 3ODKA 2Q5AA 2XP9A 4E5RA 1JMQA 3M7NA 3KAGA 2DK1A 2ZR6A 3TC5A 1K9QA 3LKXA 2YSGA 2ZR5A 2XP3A 5E66A 3FSBA 3L4HA 2E45A 4U85A 3KAFA 3LKXB 3TDBA 2YAJB 2XPAA 1WMVA 4GLXA 4U84A 2XP7A 2L4JA 1RP5A 2EZ5W 2M3OW 1FLCA 2DMVA 2ZAJA 1ZCNA 3WH0A 2DWVA 3TCZA 1NMVA 3KADA 3CNGA 5E62A 3M85A 3PQHA 3MQGA 2ZQSA 1YW5A 4QIBA 2M8JA 2JMFA 4A0TA 1WR7A 2DJYA 5U47A 2XPBA 3MQHA 2DK7A 2LAJA 2ZR4A 5CQ2A
chains in the Genus database with same CATH topology
3OOBA 5E65A 2ZQTA 3FS8A 3LE4A 3KCEA 2XP6A 5AHTA 5E5WA 2JXWA 1TK7A 1EG3A 2XP8A 1TR8A 1PINA 1O6WA 3NTPA 4U86A 2YSFA 2KXQA 1K9RA 1I5HW 2WADA 2XP4A 4A0UA 2F21A 1F8AB 2JV4A 3MCBA 2YSBA 4REXA 3KAHA 3KABA 2MDIA 2WAEA 2XP5A 1EG4A 2M8IA 3KAIA 3MCBB 2OWOA 2QRVA 2ITKA 2JX8A 2YSHA 2RE3A 2Y8NB 2ZQUA 5E64A 2YSIA 2BA1A 2ZQVA 3FSCA 3ODKA 2Q5AA 2XP9A 4E5RA 1JMQA 3M7NA 3KAGA 2DK1A 2ZR6A 3TC5A 1K9QA 3LKXA 2YSGA 2ZR5A 2XP3A 5E66A 3FSBA 3L4HA 2E45A 4U85A 3KAFA 3LKXB 3TDBA 2YAJB 2XPAA 1WMVA 4GLXA 4U84A 2XP7A 2L4JA 1RP5A 2EZ5W 2M3OW 1FLCA 2DMVA 2ZAJA 1ZCNA 3WH0A 2DWVA 3TCZA 1NMVA 3KADA 3CNGA 5E62A 3M85A 3PQHA 3MQGA 2ZQSA 1YW5A 4QIBA 2M8JA 2JMFA 4A0TA 1WR7A 2DJYA 5U47A 2XPBA 3MQHA 2DK7A 2LAJA 2ZR4A 5CQ2A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3OOB A;  2ZQT A;  3LE4 A;  3KCE A;  2XP6 A;  5AHT A;  2JXW A;  1TK7 A;  1EG3 A;  2XP8 A;  1PIN A;  1O6W A;  3NTP A;  4U86 A;  2YSF A;  2KXQ A;  1K9R A;  1I5H W;  2XP4 A;  2F21 A;  1F8A B;  2JV4 A;  2YSB A;  4REX A;  3KAH A;  3KAB A;  2MDI A;  2XP5 A;  1EG4 A;  2M8I A;  3KAI A;  2ITK A;  2JX8 A;  2YSH A;  2RE3 A;  2ZQU A;  2YSI A;  2BA1 A;  2ZQV A;  3ODK A;  2Q5A A;  2XP9 A;  4E5R A;  1JMQ A;  3M7N A;  3KAG A;  2DK1 A;  2ZR6 A;  3TC5 A;  1K9Q A;  2YSG A;  2ZR5 A;  2XP3 A;  3L4H A;  2E45 A;  4U85 A;  3KAF A;  3TDB A;  2XPA A;  1WMV A;  4U84 A;  2XP7 A;  2L4J A;  2EZ5 W;  2M3O W;  2DMV A;  2ZAJ A;  1ZCN A;  3WH0 A;  2DWV A;  3TCZ A;  1NMV A;  3KAD A;  3CNG A;  3M85 A;  2ZQS A;  1YW5 A;  4QIB A;  2M8J A;  2JMF A;  1WR7 A;  2DJY A;  2XPB A;  2DK7 A;  2LAJ A;  2ZR4 A;  5CQ2 A; 
#chains in the Genus database with same CATH topology
 3OOB A;  5E65 A;  2ZQT A;  3FS8 A;  3LE4 A;  3KCE A;  2XP6 A;  5AHT A;  5E5W A;  2JXW A;  1TK7 A;  1EG3 A;  2XP8 A;  1TR8 A;  1PIN A;  1O6W A;  3NTP A;  4U86 A;  2YSF A;  2KXQ A;  1K9R A;  1I5H W;  2WAD A;  2XP4 A;  4A0U A;  2F21 A;  1F8A B;  2JV4 A;  3MCB A;  2YSB A;  4REX A;  3KAH A;  3KAB A;  2MDI A;  2WAE A;  2XP5 A;  1EG4 A;  2M8I A;  3KAI A;  3MCB B;  2OWO A;  2QRV A;  2ITK A;  2JX8 A;  2YSH A;  2RE3 A;  2Y8N B;  2ZQU A;  5E64 A;  2YSI A;  2BA1 A;  2ZQV A;  3FSC A;  3ODK A;  2Q5A A;  2XP9 A;  4E5R A;  1JMQ A;  3M7N A;  3KAG A;  2DK1 A;  2ZR6 A;  3TC5 A;  1K9Q A;  3LKX A;  2YSG A;  2ZR5 A;  2XP3 A;  5E66 A;  3FSB A;  3L4H A;  2E45 A;  4U85 A;  3KAF A;  3LKX B;  3TDB A;  2YAJ B;  2XPA A;  1WMV A;  4GLX A;  4U84 A;  2XP7 A;  2L4J A;  1RP5 A;  2EZ5 W;  2M3O W;  1FLC A;  2DMV A;  2ZAJ A;  1ZCN A;  3WH0 A;  2DWV A;  3TCZ A;  1NMV A;  3KAD A;  3CNG A;  5E62 A;  3M85 A;  3PQH A;  3MQG A;  2ZQS A;  1YW5 A;  4QIB A;  2M8J A;  2JMF A;  4A0T A;  1WR7 A;  2DJY A;  5U47 A;  2XPB A;  3MQH A;  2DK7 A;  2LAJ A;  2ZR4 A;  5CQ2 A; 
#chains in the Genus database with same CATH homology
 3OOB A;  5E65 A;  2ZQT A;  3FS8 A;  3LE4 A;  3KCE A;  2XP6 A;  5AHT A;  5E5W A;  2JXW A;  1TK7 A;  1EG3 A;  2XP8 A;  1TR8 A;  1PIN A;  1O6W A;  3NTP A;  4U86 A;  2YSF A;  2KXQ A;  1K9R A;  1I5H W;  2WAD A;  2XP4 A;  4A0U A;  2F21 A;  1F8A B;  2JV4 A;  3MCB A;  2YSB A;  4REX A;  3KAH A;  3KAB A;  2MDI A;  2WAE A;  2XP5 A;  1EG4 A;  2M8I A;  3KAI A;  3MCB B;  2OWO A;  2QRV A;  2ITK A;  2JX8 A;  2YSH A;  2RE3 A;  2Y8N B;  2ZQU A;  5E64 A;  2YSI A;  2BA1 A;  2ZQV A;  3FSC A;  3ODK A;  2Q5A A;  2XP9 A;  4E5R A;  1JMQ A;  3M7N A;  3KAG A;  2DK1 A;  2ZR6 A;  3TC5 A;  1K9Q A;  3LKX A;  2YSG A;  2ZR5 A;  2XP3 A;  5E66 A;  3FSB A;  3L4H A;  2E45 A;  4U85 A;  3KAF A;  3LKX B;  3TDB A;  2YAJ B;  2XPA A;  1WMV A;  4GLX A;  4U84 A;  2XP7 A;  2L4J A;  1RP5 A;  2EZ5 W;  2M3O W;  1FLC A;  2DMV A;  2ZAJ A;  1ZCN A;  3WH0 A;  2DWV A;  3TCZ A;  1NMV A;  3KAD A;  3CNG A;  5E62 A;  3M85 A;  3PQH A;  3MQG A;  2ZQS A;  1YW5 A;  4QIB A;  2M8J A;  2JMF A;  4A0T A;  1WR7 A;  2DJY A;  5U47 A;  2XPB A;  3MQH A;  2DK7 A;  2LAJ A;  2ZR4 A;  5CQ2 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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