1WQKA

Solution structure of apetx1, a specific peptide inhibitor of human ether-a-go-go-related gene potassium channels from the venom of the sea anemone anthopleura elegantissima: a new fold for an herg toxin
Total Genus 4
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
42
structure length
42
Chain Sequence
GTTCYCGKTIGIYWFGTKTCPSNRGYTGSCGYFLGICCYPVD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Toxin
molecule keywords Toxin APETx1
publication title Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin
pubmed doi rcsb
total genus 4
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2004-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wqkA00
1WXNA 1BDSA 1ZLHB 1WQKA 4GV5A 1APFA 1ZLIB 2RNGA 1ATXA 1D6BA 2SH1A 2MN3A 3D4UB 3LMSB 2H9XA 1ZUEA 2JTOA 1Z99A 2MUBA 1H5OA 1SHIA 2BDSA 1ZUFA 1AHLA 1SH1A 2K2XA 1B8WA
chains in the Genus database with same CATH superfamily
1WXNA 1BDSA 2QSHA 1ZLHB 2XXLA 3C38A 1WQKA 1GKUB 4GV5A 1APFA 1ZLIB 2DLAA 2RNGA 1ATXA 1EL6A 4YIRA 1D6BA 3C30A 3MCXA 2SH1A 2MN3A 3D4UB 2HJEA 1GL9B 3LMSB 2H9XA 1ZUEA 2IKEA 1ZHHB 2JTOA 1Z99A 2IKDA 3IF4A 2QSGA 2MUBA 1H5OA 2QSFA 1SHIA 2BDSA 3MYVA 1ZUFA 2B9KA 2HJ9C 3KEZA 1AHLA 1SH1A 2JR3A 2K2XA 1B8WA
chains in the Genus database with same CATH topology
1WXNA 1BDSA 2QSHA 1ZLHB 2XXLA 3C38A 1WQKA 4GV5A 1APFA 1ZLIB 2DLAA 2RNGA 1ATXA 4YIRA 1D6BA 3C30A 3MCXA 2SH1A 2MN3A 3D4UB 2HJEA 3LMSB 2H9XA 1ZUEA 2IKEA 1ZHHB 2JTOA 1Z99A 2IKDA 2QSGA 2MUBA 1H5OA 2QSFA 1SHIA 2BDSA 3MYVA 1ZUFA 2B9KA 2HJ9C 3KEZA 1AHLA 1SH1A 2JR3A 2K2XA 1B8WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WXN A;  1BDS A;  1ZLH B;  1WQK A;  4GV5 A;  1APF A;  1ZLI B;  2RNG A;  1ATX A;  1D6B A;  2SH1 A;  2MN3 A;  3D4U B;  3LMS B;  2H9X A;  1ZUE A;  2JTO A;  1Z99 A;  2MUB A;  1H5O A;  1SHI A;  2BDS A;  1ZUF A;  1AHL A;  1SH1 A;  2K2X A;  1B8W A; 
#chains in the Genus database with same CATH topology
 1WXN A;  1BDS A;  2QSH A;  1ZLH B;  2XXL A;  3C38 A;  1WQK A;  1GKU B;  4GV5 A;  1APF A;  1ZLI B;  2DLA A;  2RNG A;  1ATX A;  1EL6 A;  4YIR A;  1D6B A;  3C30 A;  3MCX A;  2SH1 A;  2MN3 A;  3D4U B;  2HJE A;  1GL9 B;  3LMS B;  2H9X A;  1ZUE A;  2IKE A;  1ZHH B;  2JTO A;  1Z99 A;  2IKD A;  3IF4 A;  2QSG A;  2MUB A;  1H5O A;  2QSF A;  1SHI A;  2BDS A;  3MYV A;  1ZUF A;  2B9K A;  2HJ9 C;  3KEZ A;  1AHL A;  1SH1 A;  2JR3 A;  2K2X A;  1B8W A; 
#chains in the Genus database with same CATH homology
 1WXN A;  1BDS A;  2QSH A;  1ZLH B;  2XXL A;  3C38 A;  1WQK A;  4GV5 A;  1APF A;  1ZLI B;  2DLA A;  2RNG A;  1ATX A;  4YIR A;  1D6B A;  3C30 A;  3MCX A;  2SH1 A;  2MN3 A;  3D4U B;  2HJE A;  3LMS B;  2H9X A;  1ZUE A;  2IKE A;  1ZHH B;  2JTO A;  1Z99 A;  2IKD A;  2QSG A;  2MUB A;  1H5O A;  2QSF A;  1SHI A;  2BDS A;  3MYV A;  1ZUF A;  2B9K A;  2HJ9 C;  3KEZ A;  1AHL A;  1SH1 A;  2JR3 A;  2K2X A;  1B8W A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...