1WXNA

Solution structure of apetx2, a specific peptide inhibitor of asic3 proton-gated channels
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
42
structure length
42
Chain Sequence
GTACSCGNSKGIYWFYRPSCPTDRGYTGSCRYFLGTCCTPAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Toxin APETx2
publication title Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
pubmed doi rcsb
total genus 6
structure length 42
sequence length 42
ec nomenclature
pdb deposition date 2005-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07936 Defensin_4 Potassium-channel blocking toxin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 1wxnA00
1ZUEA 2RNGA 2MN3A 1WXNA 1ZUFA 1APFA 2SH1A 2H9XA 1SH1A 1ZLHB 1SHIA 1ATXA 2JTOA 3D4UB 1ZLIB 1WQKA 2MUBA 1BDSA 1B8WA 4GV5A 1H5OA 1AHLA 2K2XA 1D6BA 3LMSB 2BDSA 1Z99A
chains in the Genus database with same CATH superfamily
1ZUEA 3C38A 2RNGA 2MN3A 1WXNA 1ZUFA 1APFA 2JR3A 2SH1A 3MYVA 2H9XA 1ZLHB 1SH1A 2B9KA 1EL6A 1SHIA 2DLAA 2JTOA 3D4UB 1ATXA 3IF4A 2HJEA 2QSFA 1ZLIB 2HJ9C 4YIRA 1WQKA 2MUBA 2QSHA 1BDSA 1GL9B 2QSGA 1B8WA 4GV5A 3C30A 1H5OA 2XXLA 2IKDA 1ZHHB 3MCXA 1AHLA 2IKEA 1GKUB 2K2XA 3KEZA 1D6BA 3LMSB 2BDSA 1Z99A
chains in the Genus database with same CATH topology
1ZUEA 3C38A 2RNGA 2MN3A 1WXNA 1ZUFA 1APFA 2JR3A 2SH1A 3MYVA 2H9XA 1SH1A 1ZLHB 2B9KA 1SHIA 1ATXA 2DLAA 2JTOA 3D4UB 2HJEA 2QSFA 1ZLIB 2HJ9C 4YIRA 1WQKA 2MUBA 2QSHA 1BDSA 2QSGA 1B8WA 4GV5A 3C30A 1H5OA 2XXLA 2IKDA 1ZHHB 3MCXA 1AHLA 2IKEA 2K2XA 3KEZA 1D6BA 3LMSB 2BDSA 1Z99A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZUE A;  2RNG A;  2MN3 A;  1WXN A;  1ZUF A;  1APF A;  2SH1 A;  2H9X A;  1SH1 A;  1ZLH B;  1SHI A;  1ATX A;  2JTO A;  3D4U B;  1ZLI B;  1WQK A;  2MUB A;  1BDS A;  1B8W A;  4GV5 A;  1H5O A;  1AHL A;  2K2X A;  1D6B A;  3LMS B;  2BDS A;  1Z99 A; 
#chains in the Genus database with same CATH topology
 1ZUE A;  3C38 A;  2RNG A;  2MN3 A;  1WXN A;  1ZUF A;  1APF A;  2JR3 A;  2SH1 A;  3MYV A;  2H9X A;  1ZLH B;  1SH1 A;  2B9K A;  1EL6 A;  1SHI A;  2DLA A;  2JTO A;  3D4U B;  1ATX A;  3IF4 A;  2HJE A;  2QSF A;  1ZLI B;  2HJ9 C;  4YIR A;  1WQK A;  2MUB A;  2QSH A;  1BDS A;  1GL9 B;  2QSG A;  1B8W A;  4GV5 A;  3C30 A;  1H5O A;  2XXL A;  2IKD A;  1ZHH B;  3MCX A;  1AHL A;  2IKE A;  1GKU B;  2K2X A;  3KEZ A;  1D6B A;  3LMS B;  2BDS A;  1Z99 A; 
#chains in the Genus database with same CATH homology
 1ZUE A;  3C38 A;  2RNG A;  2MN3 A;  1WXN A;  1ZUF A;  1APF A;  2JR3 A;  2SH1 A;  3MYV A;  2H9X A;  1SH1 A;  1ZLH B;  2B9K A;  1SHI A;  1ATX A;  2DLA A;  2JTO A;  3D4U B;  2HJE A;  2QSF A;  1ZLI B;  2HJ9 C;  4YIR A;  1WQK A;  2MUB A;  2QSH A;  1BDS A;  2QSG A;  1B8W A;  4GV5 A;  3C30 A;  1H5O A;  2XXL A;  2IKD A;  1ZHH B;  3MCX A;  1AHL A;  2IKE A;  2K2X A;  3KEZ A;  1D6B A;  3LMS B;  2BDS A;  1Z99 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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