2K2XA

Solution structure of tick carboxypeptidase inhibitor at ph 3.5
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
75
structure length
75
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase inhibitor
molecule keywords Carboxypeptidase inhibitor
publication title The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
pubmed doi rcsb
source organism Rhipicephalus bursa
total genus 9
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2008-04-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2k2xA02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2k2xA01
1Z99A 2JTOA 2K2XA 2H9XA 1ZLHB 4GV5A 1WXNA 1ZLIB 2MUBA 1APFA 1WQKA 1AHLA 1BDSA 2MN3A 1ZUFA 1ATXA 1B8WA 2SH1A 2RNGA 1D6BA 2BDSA 1H5OA 1SHIA 3D4UB 1ZUEA 1SH1A 3LMSB
chains in the Genus database with same CATH superfamily
1Z99A 3MCXA 2HJEA 2JTOA 2K2XA 2H9XA 3KEZA 1ZLHB 4GV5A 4YIRA 1WXNA 2DLAA 1ZLIB 3C38A 1ZHHB 2MUBA 1APFA 1WQKA 1AHLA 2B9KA 1BDSA 2MN3A 1ZUFA 1ATXA 1B8WA 2SH1A 2RNGA 1D6BA 1EL6A 3C30A 2QSFA 2QSGA 2QSHA 2BDSA 2JR3A 1H5OA 1SHIA 3MYVA 2IKEA 3D4UB 1ZUEA 1GL9B 1SH1A 3IF4A 1GKUB 3LMSB 2XXLA 2IKDA 2HJ9C
chains in the Genus database with same CATH topology
1Z99A 3MCXA 2HJEA 2JTOA 2K2XA 2H9XA 3KEZA 1ZLHB 4GV5A 4YIRA 1WXNA 2DLAA 1ZLIB 3C38A 1ZHHB 2MUBA 1APFA 1WQKA 1AHLA 2B9KA 1BDSA 2MN3A 1ZUFA 1ATXA 1B8WA 2SH1A 2RNGA 1D6BA 3C30A 2QSFA 2QSGA 2QSHA 2BDSA 2JR3A 1H5OA 1SHIA 3MYVA 2IKEA 3D4UB 1ZUEA 1SH1A 3LMSB 2XXLA 2IKDA 2HJ9C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z99 A;  2JTO A;  2K2X A;  2H9X A;  1ZLH B;  4GV5 A;  1WXN A;  1ZLI B;  2MUB A;  1APF A;  1WQK A;  1AHL A;  1BDS A;  2MN3 A;  1ZUF A;  1ATX A;  1B8W A;  2SH1 A;  2RNG A;  1D6B A;  2BDS A;  1H5O A;  1SHI A;  3D4U B;  1ZUE A;  1SH1 A;  3LMS B; 
#chains in the Genus database with same CATH topology
 1Z99 A;  3MCX A;  2HJE A;  2JTO A;  2K2X A;  2H9X A;  3KEZ A;  1ZLH B;  4GV5 A;  4YIR A;  1WXN A;  2DLA A;  1ZLI B;  3C38 A;  1ZHH B;  2MUB A;  1APF A;  1WQK A;  1AHL A;  2B9K A;  1BDS A;  2MN3 A;  1ZUF A;  1ATX A;  1B8W A;  2SH1 A;  2RNG A;  1D6B A;  1EL6 A;  3C30 A;  2QSF A;  2QSG A;  2QSH A;  2BDS A;  2JR3 A;  1H5O A;  1SHI A;  3MYV A;  2IKE A;  3D4U B;  1ZUE A;  1GL9 B;  1SH1 A;  3IF4 A;  1GKU B;  3LMS B;  2XXL A;  2IKD A;  2HJ9 C; 
#chains in the Genus database with same CATH homology
 1Z99 A;  3MCX A;  2HJE A;  2JTO A;  2K2X A;  2H9X A;  3KEZ A;  1ZLH B;  4GV5 A;  4YIR A;  1WXN A;  2DLA A;  1ZLI B;  3C38 A;  1ZHH B;  2MUB A;  1APF A;  1WQK A;  1AHL A;  2B9K A;  1BDS A;  2MN3 A;  1ZUF A;  1ATX A;  1B8W A;  2SH1 A;  2RNG A;  1D6B A;  3C30 A;  2QSF A;  2QSG A;  2QSH A;  2BDS A;  2JR3 A;  1H5O A;  1SHI A;  3MYV A;  2IKE A;  3D4U B;  1ZUE A;  1SH1 A;  3LMS B;  2XXL A;  2IKD A;  2HJ9 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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