The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
59
|
sequence length |
184
|
structure length |
184
|
Chain Sequence |
VDLERLQALAAEWLQVIGEDPGREGLLKTPERVAKAWAFLTRGYRQRLEEVVGGAVFPAEGSEMVVVKGVEFYSMCEHHLLPFFGKVHIGYIPDGKILGLSKFARIVDMFARRLQVQERLAVQIAEAIQEVLEPQGVGVVVEGVHLCMMMRGVEKQHSRTVTSAMLGVFRENQKTREEFLSHLR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Hydrolase
|
| molecule keywords |
GTP cyclohydrolase I
|
| publication title |
Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative
pubmed doi rcsb |
| source organism |
Thermus thermophilus
|
| total genus |
59
|
| structure length |
184
|
| sequence length |
184
|
| chains with identical sequence |
B, C, D, E
|
| ec nomenclature |
ec
3.5.4.16: GTP cyclohydrolase I. |
| pdb deposition date | 2004-12-08 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01227 | GTP_cyclohydroI | GTP cyclohydrolase I |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | GTP Cyclohydrolase I; Chain A, domain 1 | GTP Cyclohydrolase I; Chain A, domain 1 | ||
| Alpha Beta | 2-Layer Sandwich | GTP Cyclohydrolase I, domain 2 | GTP Cyclohydrolase I, domain 2 |
#chains in the Genus database with same CATH superfamily 1RRW A; 2O90 A; 3BP1 A; 3O1K A; 1RSI A; 1RS2 A; 1WUR A; 1WM9 A; 1FB1 A; 1RSD A; 5F3M A; 4AEY A; 2DHN A; 4DU6 A; 3V9O A; 1IS8 A; 1FBX A; 3RJ4 A; 1GTP A; 1DHN A; 1NBU B; 5FAR A; 1NBU C; 1SQL A; 1WUQ A; 1WPL A; 1A9C A; 3RZP A; 1RRI A; 1RS4 A; 4F8B A; 4IQI A; 1U68 A; 3UXV A; 1IS7 A; 1NBU A; 2NM2 A; 2CG8 A; 3UXJ A; 1RRY A; 3R2E A; 1N3S A; 1Z9W A; 3S19 A; 1B9L A; 1N3R A; 2NM3 A; 4GHM A; 4UQF A; 1A8R A; 4FGC A; 1N3T A; #chains in the Genus database with same CATH topology 1RRW A; 3O1K A; 1FB1 A; 4QPM A; 3VEJ A; 1EFU B; 1NBU B; 5DMZ A; 3UXV A; 2LNZ A; 3B0B C; 3LW5 K; 3S19 A; 1B9L A; 2WSE K; 4FGC A; 2WSF G; 4DRA E; 3LW5 G; 1WUR A; 2DHN A; 1EL6 A; 4DRB J; 5FAR A; 1DHN A; 1NBU C; 2WSC K; 4F8B A; 4IQI A; 4NE3 B; 1U68 A; 4R8Q A; 4NE6 B; 2NM3 A; 4GHM A; 2O01 G; 1SQL A; 1RRI A; 4E45 B; 2O90 A; 1RS2 A; 1WM9 A; 4JA3 A; 4DU6 A; 3V9O A; 1IS8 A; 3BMB A; 2WSE G; 1WUQ A; 1WPL A; 1A9C A; 3RZP A; 1RS4 A; 1IS7 A; 1AIP C; 1NBU A; 2NM2 A; 3UXJ A; 2WSC G; 1RRY A; 4Q7J A; 3BP1 A; 1RSI A; 2P11 A; 1RSD A; 5F3M A; 4AEY A; 1FBX A; 3RJ4 A; 1TFE A; 2PN0 A; 1GTP A; 4E44 B; 2LO0 A; 2WSF K; 4NE5 B; 2CG8 A; 3R2E A; 1N3S A; 1Z9W A; 1N3R A; 2KR1 A; 4UQF A; 1A8R A; 1N3T A; #chains in the Genus database with same CATH homology 4DRA E; 1RRW A; 2O90 A; 3BP1 A; 3O1K A; 4FGC A; 1RSI A; 1RS2 A; 1WUR A; 1WM9 A; 2P11 A; 1FB1 A; 1RSD A; 5F3M A; 4AEY A; 4JA3 A; 4DU6 A; 2DHN A; 4QPM A; 3VEJ A; 3V9O A; 1EL6 A; 1IS8 A; 1FBX A; 3RJ4 A; 3BMB A; 4DRB J; 1EFU B; 1TFE A; 1GTP A; 2PN0 A; 1DHN A; 1NBU B; 1NBU C; 1SQL A; 1WUQ A; 5FAR A; 1WPL A; 1A9C A; 3RZP A; 1RRI A; 1RS4 A; 4F8B A; 4IQI A; 4NE3 B; 1U68 A; 3UXV A; 4E44 B; 2LO0 A; 1IS7 A; 1AIP C; 2LNZ A; 1NBU A; 2CG8 A; 4NE5 B; 2NM2 A; 4UQF A; 3UXJ A; 3B0B C; 1RRY A; 3R2E A; 1N3S A; 1Z9W A; 3S19 A; 4R8Q A; 1B9L A; 1N3R A; 4NE6 B; 2NM3 A; 4GHM A; 2KR1 A; 4Q7J A; 5DMZ A; 1A8R A; 4E45 B; 1N3T A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
