4NE5B

Human mhf1-mhf2 complex
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
molecule keywords Centromere protein S
publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
source organism Homo sapiens
total genus 22
structure length 74
sequence length 74
chains with identical sequence D, F, H
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne5B02
4NE3B 4E45B 4NE5B 4NE6B 3B0BC 4E44B 4DRAE 4DRBJ
chains in the Genus database with same CATH superfamily
1FBXA 2WSFK 4Q7JA 4JA3A 4E44B 4DRBJ 1TFEA 2PN0A 4R8QA 1GTPA 1N3SA 2LNZA 4E45B 2WSFG 1N3RA 2KR1A 3LW5K 1WUQA 3B0BC 1FB1A 1A8RA 1WPLA 1AIPC 4QPMA 2WSCK 4NE3B 1WM9A 1IS7A 2WSEK 5DMZA 1A9CA 2P11A 3LW5G 1EFUB 4DRAE 1EL6A 1IS8A 1N3TA 2LO0A 2WSCG 4NE5B 4NE6B 2O01G 1WURA 2WSEG 3BMBA 4DU6A 3VEJA
chains in the Genus database with same CATH topology
1FBXA 4Q7JA 4JA3A 4E44B 4DRBJ 1TFEA 2PN0A 4R8QA 1GTPA 1N3SA 2LNZA 4E45B 1N3RA 2KR1A 1WUQA 3B0BC 1FB1A 1A8RA 1WPLA 1AIPC 4QPMA 4NE3B 1WM9A 1IS7A 5DMZA 1A9CA 2P11A 1EFUB 4DRAE 1EL6A 1IS8A 1N3TA 2LO0A 4NE5B 4NE6B 1WURA 3BMBA 4DU6A 3VEJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NE3 B;  4E45 B;  4NE5 B;  4NE6 B;  3B0B C;  4E44 B;  4DRA E;  4DRB J; 
#chains in the Genus database with same CATH topology
 1FBX A;  2WSF K;  4Q7J A;  4JA3 A;  4E44 B;  4DRB J;  1TFE A;  2PN0 A;  4R8Q A;  1GTP A;  1N3S A;  2LNZ A;  4E45 B;  2WSF G;  1N3R A;  2KR1 A;  3LW5 K;  1WUQ A;  3B0B C;  1FB1 A;  1A8R A;  1WPL A;  1AIP C;  4QPM A;  2WSC K;  4NE3 B;  1WM9 A;  1IS7 A;  2WSE K;  5DMZ A;  1A9C A;  2P11 A;  3LW5 G;  1EFU B;  4DRA E;  1EL6 A;  1IS8 A;  1N3T A;  2LO0 A;  2WSC G;  4NE5 B;  4NE6 B;  2O01 G;  1WUR A;  2WSE G;  3BMB A;  4DU6 A;  3VEJ A; 
#chains in the Genus database with same CATH homology
 1FBX A;  4Q7J A;  4JA3 A;  4E44 B;  4DRB J;  1TFE A;  2PN0 A;  4R8Q A;  1GTP A;  1N3S A;  2LNZ A;  4E45 B;  1N3R A;  2KR1 A;  1WUQ A;  3B0B C;  1FB1 A;  1A8R A;  1WPL A;  1AIP C;  4QPM A;  4NE3 B;  1WM9 A;  1IS7 A;  5DMZ A;  1A9C A;  2P11 A;  1EFU B;  4DRA E;  1EL6 A;  1IS8 A;  1N3T A;  2LO0 A;  4NE5 B;  4NE6 B;  1WUR A;  3BMB A;  4DU6 A;  3VEJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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