2PHEA

Model for vp16 binding to pc4
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
66
structure length
66
Chain Sequence
AMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords TRANSCRIPTIONAL COACTIVATOR PC4
publication title Structural Properties of the Promiscuous VP16 Activation Domain
pubmed doi rcsb
source organism Homo sapiens
total genus 14
structure length 66
sequence length 66
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-04-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02229 PC4 Transcriptional Coactivator p15 (PC4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.31.10 Mainly Beta Roll Transcriptional Co-activator pc4; Chain A Transcriptional Coactivator Pc4; Chain A 2pheA00
4KOPA 3N1LA 4USGA 4KOQA 4AGHA 3R9YA 1L3AA 2C62A 3N1JA 3N1HA 3R9ZA 4KOOA 2NVNA 3RA0A 1PCFA 2PHEA 3N1IA 4BHMA 2IT9A 3N1KA 4BG7A
chains in the Genus database with same CATH superfamily
3OBHA 4KOPA 2M4FA 3K44A 3N1LA 4USGA 4KOQA 4AGHA 3R9YA 1L3AA 4BODA 2GIAA 2C62A 2GIDB 3N1JA 4J38A 3N1HA 2GJEA 3CM1A 3R9ZA 4KOOA 2NVNA 3RA0A 5FGPA 4BXMA 4BOBA 1PCFA 2PHEA 3MTVA 4BF3A 2GIAB 3N1IA 4BHMA 2IT9A 2GJED 2GIDA 3N1KA 4BG7A
chains in the Genus database with same CATH topology
4KOPA 3N1LA 4USGA 4KOQA 4AGHA 3R9YA 1L3AA 2C62A 3N1JA 3N1HA 3R9ZA 4KOOA 2NVNA 3RA0A 1PCFA 2PHEA 3N1IA 4BHMA 2IT9A 3N1KA 4BG7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KOP A;  3N1L A;  4USG A;  4KOQ A;  4AGH A;  3R9Y A;  1L3A A;  2C62 A;  3N1J A;  3N1H A;  3R9Z A;  4KOO A;  2NVN A;  3RA0 A;  1PCF A;  2PHE A;  3N1I A;  4BHM A;  2IT9 A;  3N1K A;  4BG7 A; 
#chains in the Genus database with same CATH topology
 3OBH A;  4KOP A;  2M4F A;  3K44 A;  3N1L A;  4USG A;  4KOQ A;  4AGH A;  3R9Y A;  1L3A A;  4BOD A;  2GIA A;  2C62 A;  2GID B;  3N1J A;  4J38 A;  3N1H A;  2GJE A;  3CM1 A;  3R9Z A;  4KOO A;  2NVN A;  3RA0 A;  5FGP A;  4BXM A;  4BOB A;  1PCF A;  2PHE A;  3MTV A;  4BF3 A;  2GIA B;  3N1I A;  4BHM A;  2IT9 A;  2GJE D;  2GID A;  3N1K A;  4BG7 A; 
#chains in the Genus database with same CATH homology
 4KOP A;  3N1L A;  4USG A;  4KOQ A;  4AGH A;  3R9Y A;  1L3A A;  2C62 A;  3N1J A;  3N1H A;  3R9Z A;  4KOO A;  2NVN A;  3RA0 A;  1PCF A;  2PHE A;  3N1I A;  4BHM A;  2IT9 A;  3N1K A;  4BG7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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