4USGA

Crystal structure of pc4 w89y mutant complex with dna
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
66
structure length
66
Chain Sequence
AMFQIGKMRYVSVRDFKGKVLIDIREYYMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15
publication title Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4.
pubmed doi rcsb
source organism Homo sapiens
total genus 16
structure length 66
sequence length 66
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02229 PC4 Transcriptional Coactivator p15 (PC4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.31.10 Mainly Beta Roll Transcriptional Co-activator pc4; Chain A Transcriptional Coactivator Pc4; Chain A 4usgA00
3R9ZA 4KOPA 1L3AA 2C62A 2PHEA 4KOOA 1PCFA 4AGHA 4USGA 4BG7A 3N1LA 3N1IA 3RA0A 3N1HA 3R9YA 3N1KA 2NVNA 4KOQA 4BHMA 2IT9A 3N1JA
chains in the Genus database with same CATH superfamily
3R9ZA 4KOPA 2GIDB 1L3AA 2C62A 2PHEA 4BODA 4KOOA 4AGHA 3MTVA 4BF3A 2GIAA 2GJED 4USGA 4BG7A 3N1LA 4BXMA 3CM1A 3N1JA 3N1IA 2GIAB 5FGPA 3RA0A 3N1HA 2GJEA 2M4FA 3R9YA 3N1KA 3OBHA 2NVNA 4BOBA 4KOQA 3K44A 4BHMA 2GIDA 4J38A 2IT9A 1PCFA
chains in the Genus database with same CATH topology
3R9ZA 4KOPA 1L3AA 2C62A 2PHEA 4KOOA 1PCFA 4AGHA 4USGA 4BG7A 3N1LA 3N1IA 3RA0A 3N1HA 3R9YA 3N1KA 2NVNA 4KOQA 4BHMA 2IT9A 3N1JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R9Z A;  4KOP A;  1L3A A;  2C62 A;  2PHE A;  4KOO A;  1PCF A;  4AGH A;  4USG A;  4BG7 A;  3N1L A;  3N1I A;  3RA0 A;  3N1H A;  3R9Y A;  3N1K A;  2NVN A;  4KOQ A;  4BHM A;  2IT9 A;  3N1J A; 
#chains in the Genus database with same CATH topology
 3R9Z A;  4KOP A;  2GID B;  1L3A A;  2C62 A;  2PHE A;  4BOD A;  4KOO A;  4AGH A;  3MTV A;  4BF3 A;  2GIA A;  2GJE D;  4USG A;  4BG7 A;  3N1L A;  4BXM A;  3CM1 A;  3N1J A;  3N1I A;  2GIA B;  5FGP A;  3RA0 A;  3N1H A;  2GJE A;  2M4F A;  3R9Y A;  3N1K A;  3OBH A;  2NVN A;  4BOB A;  4KOQ A;  3K44 A;  4BHM A;  2GID A;  4J38 A;  2IT9 A;  1PCF A; 
#chains in the Genus database with same CATH homology
 3R9Z A;  4KOP A;  1L3A A;  2C62 A;  2PHE A;  4KOO A;  1PCF A;  4AGH A;  4USG A;  4BG7 A;  3N1L A;  3N1I A;  3RA0 A;  3N1H A;  3R9Y A;  3N1K A;  2NVN A;  4KOQ A;  4BHM A;  2IT9 A;  3N1J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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