2V64D

Crystallographic structure of the conformational dimer of the spindle assembly checkpoint protein mad2.
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
181
structure length
171
Chain Sequence
EQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKGSGEKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLPQFITNSEEVRLRSFTTTIHKVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A
publication title The MAD2 Conformational Dimer: Structure and Implications for the Spindle Assembly Checkpoint
pubmed doi rcsb
source organism Homo sapiens
total genus 55
structure length 171
sequence length 181
chains with identical sequence E, H
ec nomenclature
pdb deposition date 2007-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF02301 HORMA HORMA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.900.10 Alpha Beta 2-Layer Sandwich Cell Cycle, Spindle Assembly Checkpoint Protein; Chain A HORMA domain 2v64D00
4TZJA 4YK8B 4GK5A 1GO4A 3ABEC 5LCWZ 4TZSA 2VFXA 3GMHA 5C50B 4TZLA 3ABDA 4TZOA 4TZQA 4AEZB 4TRKA 4FJOC 3VU7C 2QYFA 1S2HA 1KLQA 4EXTC 1DUJA 4TZMA 4GK0A 2V64A 4J2GA 4TZNA 2V64D
chains in the Genus database with same CATH superfamily
4TZJA 4YK8B 4GK5A 1GO4A 3ABEC 5LCWZ 4TZSA 2VFXA 3GMHA 5C50B 4TZLA 3ABDA 4TZOA 4TZQA 4AEZB 4TRKA 4FJOC 3VU7C 2QYFB 2QYFA 1S2HA 1KLQA 4EXTC 1DUJA 4TZMA 4GK0A 2V64A 4J2GA 4TZNA 2V64D
chains in the Genus database with same CATH topology
4TZJA 4YK8B 4GK5A 1GO4A 3ABEC 5LCWZ 4TZSA 2VFXA 3GMHA 5C50B 4TZLA 3ABDA 4TZOA 4TZQA 4AEZB 4TRKA 4FJOC 3VU7C 2QYFA 1S2HA 1KLQA 4EXTC 1DUJA 4TZMA 4GK0A 2V64A 4J2GA 4TZNA 2V64D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TZJ A;  4YK8 B;  4GK5 A;  1GO4 A;  3ABE C;  5LCW Z;  4TZS A;  2VFX A;  3GMH A;  5C50 B;  4TZL A;  3ABD A;  4TZO A;  4TZQ A;  4AEZ B;  4TRK A;  4FJO C;  3VU7 C;  2QYF A;  1S2H A;  1KLQ A;  4EXT C;  1DUJ A;  4TZM A;  4GK0 A;  2V64 A;  4J2G A;  4TZN A;  2V64 D; 
#chains in the Genus database with same CATH topology
 4TZJ A;  4YK8 B;  4GK5 A;  1GO4 A;  3ABE C;  5LCW Z;  4TZS A;  2VFX A;  3GMH A;  5C50 B;  4TZL A;  3ABD A;  4TZO A;  4TZQ A;  4AEZ B;  4TRK A;  4FJO C;  3VU7 C;  2QYF B;  2QYF A;  1S2H A;  1KLQ A;  4EXT C;  1DUJ A;  4TZM A;  4GK0 A;  2V64 A;  4J2G A;  4TZN A;  2V64 D; 
#chains in the Genus database with same CATH homology
 4TZJ A;  4YK8 B;  4GK5 A;  1GO4 A;  3ABE C;  5LCW Z;  4TZS A;  2VFX A;  3GMH A;  5C50 B;  4TZL A;  3ABD A;  4TZO A;  4TZQ A;  4AEZ B;  4TRK A;  4FJO C;  3VU7 C;  2QYF A;  1S2H A;  1KLQ A;  4EXT C;  1DUJ A;  4TZM A;  4GK0 A;  2V64 A;  4J2G A;  4TZN A;  2V64 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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