2YPAB

Structure of the scl:e47:lmo2:ldb1 complex bound to dna
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
73
structure length
73
Chain Sequence
EKDLRDRERRMANNARERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1
publication title Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
pubmed doi rcsb
source organism Homo sapiens
total genus 28
structure length 73
sequence length 73
ec nomenclature
pdb deposition date 2012-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 2ypaB00
1MDYB 3MUJA 1NLWB 1NKPA 2QL2B 5I50A 2YPAB 1UKLC 4ATIA 5I4ZA 2YPBA 4H10B 4F3LA 4ATKA 1A0AA 1R05A 1MDYA 1NKPB 4AYAA 5EYOA 4ATHA 1NLWA 2QL2A 2YPAA 2MH3A 1HLOA 1AN4A 1AN2A 2LFHA 2YPBB 3U5VA 4F3LB 1AM9A 4H10A
chains in the Genus database with same CATH superfamily
1MDYB 3MUJA 1NLWB 1NKPA 2QL2B 5I50A 2YPAB 1ZZAA 1UKLC 4ATIA 5I4ZA 2YPBA 4H10B 4F3LA 4ATKA 1A0AA 1R05A 1MDYA 1NKPB 4AYAA 5EYOA 4ATHA 1NLWA 2QL2A 1K1FA 2YPAA 2MH3A 1HLOA 1AN4A 1AN2A 2LFHA 2YPBB 3U5VA 4F3LB 1AM9A 4H10A
chains in the Genus database with same CATH topology
1MDYB 3MUJA 1NLWB 1NKPA 2QL2B 5I50A 2YPAB 1UKLC 4ATIA 5I4ZA 2YPBA 4H10B 4F3LA 4ATKA 1A0AA 1R05A 1MDYA 1NKPB 4AYAA 5EYOA 4ATHA 1NLWA 2QL2A 2YPAA 2MH3A 1HLOA 1AN4A 1AN2A 2LFHA 2YPBB 3U5VA 4F3LB 1AM9A 4H10A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MDY B;  3MUJ A;  1NLW B;  1NKP A;  2QL2 B;  5I50 A;  2YPA B;  1UKL C;  4ATI A;  5I4Z A;  2YPB A;  4H10 B;  4F3L A;  4ATK A;  1A0A A;  1R05 A;  1MDY A;  1NKP B;  4AYA A;  5EYO A;  4ATH A;  1NLW A;  2QL2 A;  2YPA A;  2MH3 A;  1HLO A;  1AN4 A;  1AN2 A;  2LFH A;  2YPB B;  3U5V A;  4F3L B;  1AM9 A;  4H10 A; 
#chains in the Genus database with same CATH topology
 1MDY B;  3MUJ A;  1NLW B;  1NKP A;  2QL2 B;  5I50 A;  2YPA B;  1ZZA A;  1UKL C;  4ATI A;  5I4Z A;  2YPB A;  4H10 B;  4F3L A;  4ATK A;  1A0A A;  1R05 A;  1MDY A;  1NKP B;  4AYA A;  5EYO A;  4ATH A;  1NLW A;  2QL2 A;  1K1F A;  2YPA A;  2MH3 A;  1HLO A;  1AN4 A;  1AN2 A;  2LFH A;  2YPB B;  3U5V A;  4F3L B;  1AM9 A;  4H10 A; 
#chains in the Genus database with same CATH homology
 1MDY B;  3MUJ A;  1NLW B;  1NKP A;  2QL2 B;  5I50 A;  2YPA B;  1UKL C;  4ATI A;  5I4Z A;  2YPB A;  4H10 B;  4F3L A;  4ATK A;  1A0A A;  1R05 A;  1MDY A;  1NKP B;  4AYA A;  5EYO A;  4ATH A;  1NLW A;  2QL2 A;  2YPA A;  2MH3 A;  1HLO A;  1AN4 A;  1AN2 A;  2LFH A;  2YPB B;  3U5V A;  4F3L B;  1AM9 A;  4H10 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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