4H10B

Intermolecular recognition revealed by the complex structure of human clock-bmal1 basic helix-loop-helix domains with e-box dna
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
63
structure length
63
Chain Sequence
KDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAWLEH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/dna
molecule keywords Aryl hydrocarbon receptor nuclear translocator-like protein
publication title Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.
pubmed doi rcsb
source organism Homo sapiens
total genus 24
structure length 63
sequence length 63
ec nomenclature ec 2.3.1.48: Histone acetyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 4h10B00
5I4ZA 1NKPA 2YPBB 1MDYA 2YPAB 4ATIA 1HLOA 2YPBA 1UKLC 1AM9A 2YPAA 5I50A 4H10B 1A0AA 1NLWB 2MH3A 4H10A 5EYOA 3MUJA 4ATHA 1NLWA 1R05A 1AN2A 2LFHA 4F3LB 1AN4A 4F3LA 4AYAA 4ATKA 2QL2B 1NKPB 3U5VA 2QL2A 1MDYB
chains in the Genus database with same CATH superfamily
5I4ZA 1NKPA 2YPBB 1MDYA 2YPAB 4ATIA 1HLOA 1ZZAA 1UKLC 2YPBA 1AM9A 2YPAA 5I50A 4H10B 1A0AA 1NLWB 2MH3A 4H10A 5EYOA 3MUJA 4ATHA 1NLWA 1R05A 1AN2A 1K1FA 2LFHA 4F3LB 1AN4A 4F3LA 4AYAA 4ATKA 2QL2B 1NKPB 3U5VA 2QL2A 1MDYB
chains in the Genus database with same CATH topology
5I4ZA 1NKPA 2YPBB 1MDYA 2YPAB 4ATIA 1HLOA 2YPBA 1UKLC 1AM9A 2YPAA 5I50A 4H10B 1A0AA 1NLWB 2MH3A 4H10A 5EYOA 3MUJA 4ATHA 1NLWA 1R05A 1AN2A 2LFHA 4F3LB 1AN4A 4F3LA 4AYAA 4ATKA 2QL2B 1NKPB 3U5VA 2QL2A 1MDYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I4Z A;  1NKP A;  2YPB B;  1MDY A;  2YPA B;  4ATI A;  1HLO A;  2YPB A;  1UKL C;  1AM9 A;  2YPA A;  5I50 A;  4H10 B;  1A0A A;  1NLW B;  2MH3 A;  4H10 A;  5EYO A;  3MUJ A;  4ATH A;  1NLW A;  1R05 A;  1AN2 A;  2LFH A;  4F3L B;  1AN4 A;  4F3L A;  4AYA A;  4ATK A;  2QL2 B;  1NKP B;  3U5V A;  2QL2 A;  1MDY B; 
#chains in the Genus database with same CATH topology
 5I4Z A;  1NKP A;  2YPB B;  1MDY A;  2YPA B;  4ATI A;  1HLO A;  1ZZA A;  1UKL C;  2YPB A;  1AM9 A;  2YPA A;  5I50 A;  4H10 B;  1A0A A;  1NLW B;  2MH3 A;  4H10 A;  5EYO A;  3MUJ A;  4ATH A;  1NLW A;  1R05 A;  1AN2 A;  1K1F A;  2LFH A;  4F3L B;  1AN4 A;  4F3L A;  4AYA A;  4ATK A;  2QL2 B;  1NKP B;  3U5V A;  2QL2 A;  1MDY B; 
#chains in the Genus database with same CATH homology
 5I4Z A;  1NKP A;  2YPB B;  1MDY A;  2YPA B;  4ATI A;  1HLO A;  2YPB A;  1UKL C;  1AM9 A;  2YPA A;  5I50 A;  4H10 B;  1A0A A;  1NLW B;  2MH3 A;  4H10 A;  5EYO A;  3MUJ A;  4ATH A;  1NLW A;  1R05 A;  1AN2 A;  2LFH A;  4F3L B;  1AN4 A;  4F3L A;  4AYA A;  4ATK A;  2QL2 B;  1NKP B;  3U5V A;  2QL2 A;  1MDY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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