5I4ZA

Structure of apo omomyc
Total Genus 30
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
74
structure length
74
Chain Sequence
RRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAETQKLISEIDLLRKQNEQLKHKLEQLRNSCA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transcription
molecule keywords Myc proto-oncogene protein
publication title OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
pubmed doi rcsb
source organism Homo sapiens
total genus 30
structure length 74
sequence length 74
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
A PF02344 Myc-LZ Myc leucine zipper domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 5i4zA00
5I4ZA 4H10A 1HLOA 2LFHA 5EYOA 5I50A 1NLWB 2YPBA 2MH3A 4ATKA 4ATIA 1NKPA 2QL2A 1MDYB 2YPAA 1A0AA 4F3LB 4ATHA 1AN4A 1AM9A 2YPAB 1AN2A 1UKLC 1NLWA 1R05A 3U5VA 1MDYA 4H10B 4F3LA 4AYAA 2YPBB 3MUJA 2QL2B 1NKPB
chains in the Genus database with same CATH superfamily
5I4ZA 4H10A 1HLOA 2LFHA 5EYOA 5I50A 1NLWB 2YPBA 2MH3A 4ATKA 4ATIA 1NKPA 1K1FA 2QL2A 1MDYB 2YPAA 1A0AA 4F3LB 4ATHA 1ZZAA 1AN4A 1AM9A 2YPAB 1AN2A 1UKLC 1NLWA 1R05A 3U5VA 1MDYA 4H10B 4F3LA 4AYAA 2YPBB 3MUJA 2QL2B 1NKPB
chains in the Genus database with same CATH topology
5I4ZA 4H10A 1HLOA 2LFHA 5EYOA 5I50A 1NLWB 2YPBA 2MH3A 4ATKA 4ATIA 1NKPA 2QL2A 1MDYB 2YPAA 1A0AA 4F3LB 4ATHA 1AN4A 1AM9A 2YPAB 1AN2A 1UKLC 1NLWA 1R05A 3U5VA 1MDYA 4H10B 4F3LA 4AYAA 2YPBB 3MUJA 2QL2B 1NKPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I4Z A;  4H10 A;  1HLO A;  2LFH A;  5EYO A;  5I50 A;  1NLW B;  2YPB A;  2MH3 A;  4ATK A;  4ATI A;  1NKP A;  2QL2 A;  1MDY B;  2YPA A;  1A0A A;  4F3L B;  4ATH A;  1AN4 A;  1AM9 A;  2YPA B;  1AN2 A;  1UKL C;  1NLW A;  1R05 A;  3U5V A;  1MDY A;  4H10 B;  4F3L A;  4AYA A;  2YPB B;  3MUJ A;  2QL2 B;  1NKP B; 
#chains in the Genus database with same CATH topology
 5I4Z A;  4H10 A;  1HLO A;  2LFH A;  5EYO A;  5I50 A;  1NLW B;  2YPB A;  2MH3 A;  4ATK A;  4ATI A;  1NKP A;  1K1F A;  2QL2 A;  1MDY B;  2YPA A;  1A0A A;  4F3L B;  4ATH A;  1ZZA A;  1AN4 A;  1AM9 A;  2YPA B;  1AN2 A;  1UKL C;  1NLW A;  1R05 A;  3U5V A;  1MDY A;  4H10 B;  4F3L A;  4AYA A;  2YPB B;  3MUJ A;  2QL2 B;  1NKP B; 
#chains in the Genus database with same CATH homology
 5I4Z A;  4H10 A;  1HLO A;  2LFH A;  5EYO A;  5I50 A;  1NLW B;  2YPB A;  2MH3 A;  4ATK A;  4ATI A;  1NKP A;  2QL2 A;  1MDY B;  2YPA A;  1A0A A;  4F3L B;  4ATH A;  1AN4 A;  1AM9 A;  2YPA B;  1AN2 A;  1UKL C;  1NLW A;  1R05 A;  3U5V A;  1MDY A;  4H10 B;  4F3L A;  4AYA A;  2YPB B;  3MUJ A;  2QL2 B;  1NKP B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...