5I50A

Structure of omomyc bound to double-stranded dna
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
92
structure length
92
Chain Sequence
MATEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAETQKLISEIDLLRKQNEQLKHKLEQLRNSCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Myc proto-oncogene protein
total genus 41
structure length 92
sequence length 92
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
A PF02344 Myc-LZ Myc leucine zipper domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 5i50A00
3U5VA 2LFHA 5I50A 1AN2A 2YPAB 2QL2A 1A0AA 1NLWB 1NKPA 4AYAA 4H10B 5EYOA 5I4ZA 3MUJA 1MDYA 4F3LA 1AM9A 1AN4A 1NLWA 4ATKA 2YPBB 2YPAA 4H10A 4ATIA 1UKLC 1R05A 2QL2B 1HLOA 1NKPB 2MH3A 2YPBA 1MDYB 4F3LB 4ATHA
chains in the Genus database with same CATH superfamily
3U5VA 2LFHA 5I50A 1AN2A 2YPAB 1ZZAA 2QL2A 1A0AA 1NLWB 1NKPA 4AYAA 4H10B 5EYOA 1K1FA 5I4ZA 3MUJA 1MDYA 4F3LA 1AM9A 1AN4A 1NLWA 4ATKA 2YPBB 2YPAA 4H10A 4ATIA 1UKLC 1R05A 2QL2B 1HLOA 1NKPB 2MH3A 2YPBA 1MDYB 4F3LB 4ATHA
chains in the Genus database with same CATH topology
3U5VA 2LFHA 5I50A 1AN2A 2YPAB 2QL2A 1A0AA 1NLWB 1NKPA 4AYAA 4H10B 5EYOA 5I4ZA 3MUJA 1MDYA 4F3LA 1AM9A 1AN4A 1NLWA 4ATKA 2YPBB 2YPAA 4H10A 4ATIA 1UKLC 1R05A 2QL2B 1HLOA 1NKPB 2MH3A 2YPBA 1MDYB 4F3LB 4ATHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3U5V A;  2LFH A;  5I50 A;  1AN2 A;  2YPA B;  2QL2 A;  1A0A A;  1NLW B;  1NKP A;  4AYA A;  4H10 B;  5EYO A;  5I4Z A;  3MUJ A;  1MDY A;  4F3L A;  1AM9 A;  1AN4 A;  1NLW A;  4ATK A;  2YPB B;  2YPA A;  4H10 A;  4ATI A;  1UKL C;  1R05 A;  2QL2 B;  1HLO A;  1NKP B;  2MH3 A;  2YPB A;  1MDY B;  4F3L B;  4ATH A; 
#chains in the Genus database with same CATH topology
 3U5V A;  2LFH A;  5I50 A;  1AN2 A;  2YPA B;  1ZZA A;  2QL2 A;  1A0A A;  1NLW B;  1NKP A;  4AYA A;  4H10 B;  5EYO A;  1K1F A;  5I4Z A;  3MUJ A;  1MDY A;  4F3L A;  1AM9 A;  1AN4 A;  1NLW A;  4ATK A;  2YPB B;  2YPA A;  4H10 A;  4ATI A;  1UKL C;  1R05 A;  2QL2 B;  1HLO A;  1NKP B;  2MH3 A;  2YPB A;  1MDY B;  4F3L B;  4ATH A; 
#chains in the Genus database with same CATH homology
 3U5V A;  2LFH A;  5I50 A;  1AN2 A;  2YPA B;  2QL2 A;  1A0A A;  1NLW B;  1NKP A;  4AYA A;  4H10 B;  5EYO A;  5I4Z A;  3MUJ A;  1MDY A;  4F3L A;  1AM9 A;  1AN4 A;  1NLW A;  4ATK A;  2YPB B;  2YPA A;  4H10 A;  4ATI A;  1UKL C;  1R05 A;  2QL2 B;  1HLO A;  1NKP B;  2MH3 A;  2YPB A;  1MDY B;  4F3L B;  4ATH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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