2ZKFA

Crystal structure of the sra domain of mouse np95 in complex with hemi-methylated cpg dna
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
209
structure length
209
Chain Sequence
GMACVGRTTECTIVPANHFGPIPGVPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDNGNYFTYTGSGGRDLSGNKRTAGQSSDQKLTNNNRALALNCHSPINEKGAEAEDWRQGKPVRVVRNMKGGKHSKYAPAEGNRYDGIYKVVKYWPERGKSGFLVWRYLLRRDDTEPEPWTREGKDRTRQLGLTMQYPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Ligase
molecule keywords E3 ubiquitin-protein ligase UHRF1
publication title Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
pubmed doi rcsb
source organism Mus musculus
total genus 57
structure length 209
sequence length 209
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 2zkfA00
2ZKFA 2ZKEA 3OLNA 2ZO1B 3CLZA 2ZKDA 4PW5A 4PW7A 2ZO0B 2PB7A 3DWHA 3FDEA 3F8IA 2ZKGA 2ZO2B 4PW6A 4NJ5A 3F8JB 3BI7A
chains in the Genus database with same CATH superfamily
4YGIA 2ZKFA 3BI7A 2ZKEA 3OLNA 4RZLA 4F0PA 3Q0BX 2ZO1B 3CLZA 2ZKDA 4PW5A 4OC8A 4R28A 4PW7A 3Q0DA 2ZO0B 3Q0CA 2PB7A 3DWHA 3FDEA 3F8IA 2ZKGA 2ZO2B 4PW6A 4NJ5A 3F8JB 4F0QA 3Q0FA
chains in the Genus database with same CATH topology
2ZKFA 2ZKEA 3OLNA 2ZO1B 3CLZA 2ZKDA 4PW5A 4PW7A 2ZO0B 2PB7A 3DWHA 3FDEA 3F8IA 2ZKGA 2ZO2B 4PW6A 4NJ5A 3F8JB 3BI7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZKF A;  2ZKE A;  3OLN A;  2ZO1 B;  3CLZ A;  2ZKD A;  4PW5 A;  4PW7 A;  2ZO0 B;  2PB7 A;  3DWH A;  3FDE A;  3F8I A;  2ZKG A;  2ZO2 B;  4PW6 A;  4NJ5 A;  3F8J B;  3BI7 A; 
#chains in the Genus database with same CATH topology
 4YGI A;  2ZKF A;  3BI7 A;  2ZKE A;  3OLN A;  4RZL A;  4F0P A;  3Q0B X;  2ZO1 B;  3CLZ A;  2ZKD A;  4PW5 A;  4OC8 A;  4R28 A;  4PW7 A;  3Q0D A;  2ZO0 B;  3Q0C A;  2PB7 A;  3DWH A;  3FDE A;  3F8I A;  2ZKG A;  2ZO2 B;  4PW6 A;  4NJ5 A;  3F8J B;  4F0Q A;  3Q0F A; 
#chains in the Genus database with same CATH homology
 2ZKF A;  2ZKE A;  3OLN A;  2ZO1 B;  3CLZ A;  2ZKD A;  4PW5 A;  4PW7 A;  2ZO0 B;  2PB7 A;  3DWH A;  3FDE A;  3F8I A;  2ZKG A;  2ZO2 B;  4PW6 A;  4NJ5 A;  3F8J B;  3BI7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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