3BI7A

Crystal structure of the sra domain of e3 ubiquitin-protein ligase uhrf1
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
206
structure length
194
Chain Sequence
PSNHYGPIPGIPVGTMWRFRVQVSESGVHRPHVAGIHGRSNDGAYSLVLAGGYEDDVDHGNFFTYTGSGGSCDQKLTNTNRALALNCFAPINDQEGAEAKDWRSGKPVRVVRNVKGGKNSKYAPAEGNRYDGIYKVVKYWPEKGKSGFLVWRYLLRRDDDEPGPWTKEGKDRIKKLGLTMQYPEGYLEALANAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Ligase
molecule keywords E3 ubiquitin-protein ligase UHRF1
publication title Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.
pubmed doi rcsb
source organism Homo sapiens
total genus 57
structure length 194
sequence length 206
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 3bi7A01
2ZKEA 2ZKFA 4NJ5A 3F8JB 2ZKDA 2PB7A 3FDEA 4PW7A 3DWHA 3CLZA 3OLNA 3F8IA 2ZKGA 3BI7A 2ZO0B 4PW5A 2ZO2B 2ZO1B 4PW6A
chains in the Genus database with same CATH superfamily
2ZKEA 2ZKFA 4NJ5A 4OC8A 3F8JB 2ZKDA 2PB7A 3FDEA 4PW7A 4YGIA 4R28A 3Q0CA 3Q0DA 3DWHA 3CLZA 4F0PA 3OLNA 3F8IA 2ZKGA 3BI7A 3Q0FA 3Q0BX 2ZO0B 4RZLA 2ZO2B 4PW5A 4F0QA 2ZO1B 4PW6A
chains in the Genus database with same CATH topology
2ZKEA 2ZKFA 4NJ5A 3F8JB 2ZKDA 2PB7A 3FDEA 4PW7A 3DWHA 3CLZA 3OLNA 3F8IA 2ZKGA 3BI7A 2ZO0B 4PW5A 2ZO2B 2ZO1B 4PW6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZKE A;  2ZKF A;  4NJ5 A;  3F8J B;  2ZKD A;  2PB7 A;  3FDE A;  4PW7 A;  3DWH A;  3CLZ A;  3OLN A;  3F8I A;  2ZKG A;  3BI7 A;  2ZO0 B;  4PW5 A;  2ZO2 B;  2ZO1 B;  4PW6 A; 
#chains in the Genus database with same CATH topology
 2ZKE A;  2ZKF A;  4NJ5 A;  4OC8 A;  3F8J B;  2ZKD A;  2PB7 A;  3FDE A;  4PW7 A;  4YGI A;  4R28 A;  3Q0C A;  3Q0D A;  3DWH A;  3CLZ A;  4F0P A;  3OLN A;  3F8I A;  2ZKG A;  3BI7 A;  3Q0F A;  3Q0B X;  2ZO0 B;  4RZL A;  2ZO2 B;  4PW5 A;  4F0Q A;  2ZO1 B;  4PW6 A; 
#chains in the Genus database with same CATH homology
 2ZKE A;  2ZKF A;  4NJ5 A;  3F8J B;  2ZKD A;  2PB7 A;  3FDE A;  4PW7 A;  3DWH A;  3CLZ A;  3OLN A;  3F8I A;  2ZKG A;  3BI7 A;  2ZO0 B;  4PW5 A;  2ZO2 B;  2ZO1 B;  4PW6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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