4PW7A

Structure of uhrf2-sra in complex with a 5mc-containing dna
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
202
structure length
197
Chain Sequence
IVPSNHYGPIPGIPVGSTWRFRVQVSEAGVHRPHVGGIHGRSNDGAYSLVLAGGFADEVDRGDEFTYTGSGGKKRIGAPSADQTLTNMNRALALNCDAPLDDKIGAESRNWRAGKPVRVIRSFKGRKISKYAPEEGNRYDGIYKVVKYWPEISSSHGFLVWRYLLRRDDVEPAPWTSEGIERSRRLCLRLQYPAGYP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Ligase/dna
molecule keywords E3 ubiquitin-protein ligase UHRF2
publication title Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2.
pubmed doi rcsb
source organism Homo sapiens
total genus 60
structure length 197
sequence length 202
chains with identical sequence B, E, F
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2014-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02182 SAD_SRA SAD/SRA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.10 Mainly Beta Roll PUA domain-like SRA-YDG 4pw7A01
3BI7A 2ZKEA 4PW6A 2ZO0B 2ZKGA 2PB7A 2ZKDA 3FDEA 3OLNA 4PW7A 2ZKFA 2ZO2B 4NJ5A 3CLZA 2ZO1B 3F8IA 3F8JB 3DWHA 4PW5A
chains in the Genus database with same CATH superfamily
4YGIA 3Q0BX 3BI7A 2ZKEA 4F0QA 4F0PA 4R28A 4PW6A 3Q0FA 2ZO0B 2ZKGA 3DWHA 3Q0DA 2PB7A 2ZKDA 3FDEA 3OLNA 4PW7A 2ZKFA 2ZO2B 4PW5A 4RZLA 4NJ5A 3CLZA 2ZO1B 3F8IA 3F8JB 3Q0CA 4OC8A
chains in the Genus database with same CATH topology
3BI7A 2ZKEA 4PW6A 2ZO0B 2ZKGA 2PB7A 2ZKDA 3FDEA 3OLNA 4PW7A 2ZKFA 2ZO2B 4NJ5A 3CLZA 2ZO1B 3F8IA 3F8JB 3DWHA 4PW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BI7 A;  2ZKE A;  4PW6 A;  2ZO0 B;  2ZKG A;  2PB7 A;  2ZKD A;  3FDE A;  3OLN A;  4PW7 A;  2ZKF A;  2ZO2 B;  4NJ5 A;  3CLZ A;  2ZO1 B;  3F8I A;  3F8J B;  3DWH A;  4PW5 A; 
#chains in the Genus database with same CATH topology
 4YGI A;  3Q0B X;  3BI7 A;  2ZKE A;  4F0Q A;  4F0P A;  4R28 A;  4PW6 A;  3Q0F A;  2ZO0 B;  2ZKG A;  3DWH A;  3Q0D A;  2PB7 A;  2ZKD A;  3FDE A;  3OLN A;  4PW7 A;  2ZKF A;  2ZO2 B;  4PW5 A;  4RZL A;  4NJ5 A;  3CLZ A;  2ZO1 B;  3F8I A;  3F8J B;  3Q0C A;  4OC8 A; 
#chains in the Genus database with same CATH homology
 3BI7 A;  2ZKE A;  4PW6 A;  2ZO0 B;  2ZKG A;  2PB7 A;  2ZKD A;  3FDE A;  3OLN A;  4PW7 A;  2ZKF A;  2ZO2 B;  4NJ5 A;  3CLZ A;  2ZO1 B;  3F8I A;  3F8J B;  3DWH A;  4PW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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