2ZMXB

Crystal structure of the met1-form of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking in cupric sulfate solution for 36 hours
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
83
structure length
77
Chain Sequence
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVVSHYDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/metal transport
molecule keywords Tyrosinase
publication title Crystallographic Evidence That the Dinuclear Copper Center of Tyrosinase Is Flexible during Catalysis
pubmed doi rcsb
source organism Streptomyces castaneoglobisporus
total genus 17
structure length 77
sequence length 83
ec nomenclature
pdb deposition date 2008-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zmxB01
1WX2B 3AWYB 2ZWEB 2JV8A 3AWWB 2ZMZB 2ZMXB 2ZWDB 3AWVB 3AWZB 3AX0B 3AWTB 2ZWGB 1WXCB 1WX4B 2AHKB 2ZWFB 2AHLB 1WX5B 3AWSB 3AWUB 3AWXB 2ZMYB
chains in the Genus database with same CATH superfamily
4NBHA 2DE7A 1WX2B 3AWYB 1WW9A 3GKQA 2ZWEB 4NBAA 4NBEA 1Z01A 4NB8A 4NBBA 2JV8A 2DE6A 2ZMZB 2ZMXB 2ZWDB 1Z03A 3AWWB 3AWVB 3VMGA 3AWZB 4NB9A 3AX0B 3AWTB 2ZWGB 1WXCB 1WX4B 2AHKB 4NBCA 1Z02A 2ZWFB 2AHLB 4NBFA 1WX5B 4NBDA 3AWSB 3AWUB 3VMIA 3AWXB 4NBGA 2ZMYB 3GCFA 3VMHA 2DE5A
chains in the Genus database with same CATH topology
1WX2B 3AWYB 2ZWEB 2JV8A 3AWWB 2ZMZB 2ZMXB 2ZWDB 3AWVB 3AWZB 3AX0B 3AWTB 2ZWGB 1WXCB 1WX4B 2AHKB 2ZWFB 2AHLB 1WX5B 3AWSB 3AWUB 3AWXB 2ZMYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WX2 B;  3AWY B;  2ZWE B;  2JV8 A;  3AWW B;  2ZMZ B;  2ZMX B;  2ZWD B;  3AWV B;  3AWZ B;  3AX0 B;  3AWT B;  2ZWG B;  1WXC B;  1WX4 B;  2AHK B;  2ZWF B;  2AHL B;  1WX5 B;  3AWS B;  3AWU B;  3AWX B;  2ZMY B; 
#chains in the Genus database with same CATH topology
 4NBH A;  2DE7 A;  1WX2 B;  3AWY B;  1WW9 A;  3GKQ A;  2ZWE B;  4NBA A;  4NBE A;  1Z01 A;  4NB8 A;  4NBB A;  2JV8 A;  2DE6 A;  2ZMZ B;  2ZMX B;  2ZWD B;  1Z03 A;  3AWW B;  3AWV B;  3VMG A;  3AWZ B;  4NB9 A;  3AX0 B;  3AWT B;  2ZWG B;  1WXC B;  1WX4 B;  2AHK B;  4NBC A;  1Z02 A;  2ZWF B;  2AHL B;  4NBF A;  1WX5 B;  4NBD A;  3AWS B;  3AWU B;  3VMI A;  3AWX B;  4NBG A;  2ZMY B;  3GCF A;  3VMH A;  2DE5 A; 
#chains in the Genus database with same CATH homology
 1WX2 B;  3AWY B;  2ZWE B;  2JV8 A;  3AWW B;  2ZMZ B;  2ZMX B;  2ZWD B;  3AWV B;  3AWZ B;  3AX0 B;  3AWT B;  2ZWG B;  1WXC B;  1WX4 B;  2AHK B;  2ZWF B;  2AHL B;  1WX5 B;  3AWS B;  3AWU B;  3AWX B;  2ZMY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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