2ZWEB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 40 minutes
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
84
structure length
77
Chain Sequence
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/metal transport
molecule keywords Tyrosinase
publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
source organism Streptomyces castaneoglobisporus
total genus 16
structure length 77
sequence length 84
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zweB01
2ZMYB 2ZWGB 2ZMZB 3AWTB 3AWSB 2JV8A 3AWZB 1WX5B 2AHKB 2ZWDB 3AWYB 3AWUB 3AX0B 3AWXB 3AWVB 1WX2B 2ZWFB 2AHLB 1WX4B 2ZWEB 3AWWB 1WXCB 2ZMXB
chains in the Genus database with same CATH superfamily
2DE6A 2ZMYB 4NBEA 1WW9A 2DE7A 2ZWGB 3GCFA 2ZMZB 3AWTB 1Z03A 3GKQA 4NBCA 3AWSB 4NB9A 4NBGA 2JV8A 4NBDA 4NBAA 3AWZB 3VMGA 3VMIA 1WX5B 2AHKB 3VMHA 2ZWDB 3AWYB 3AWUB 4NB8A 3AX0B 3AWXB 3AWVB 4NBFA 1WX2B 2DE5A 2ZWFB 2AHLB 1Z02A 1Z01A 1WX4B 2ZWEB 3AWWB 1WXCB 4NBBA 2ZMXB 4NBHA
chains in the Genus database with same CATH topology
2ZMYB 2ZWGB 2ZMZB 3AWTB 3AWSB 2JV8A 3AWZB 1WX5B 2AHKB 2ZWDB 3AWYB 3AWUB 3AX0B 3AWXB 3AWVB 1WX2B 2ZWFB 2AHLB 1WX4B 2ZWEB 3AWWB 1WXCB 2ZMXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZMY B;  2ZWG B;  2ZMZ B;  3AWT B;  3AWS B;  2JV8 A;  3AWZ B;  1WX5 B;  2AHK B;  2ZWD B;  3AWY B;  3AWU B;  3AX0 B;  3AWX B;  3AWV B;  1WX2 B;  2ZWF B;  2AHL B;  1WX4 B;  2ZWE B;  3AWW B;  1WXC B;  2ZMX B; 
#chains in the Genus database with same CATH topology
 2DE6 A;  2ZMY B;  4NBE A;  1WW9 A;  2DE7 A;  2ZWG B;  3GCF A;  2ZMZ B;  3AWT B;  1Z03 A;  3GKQ A;  4NBC A;  3AWS B;  4NB9 A;  4NBG A;  2JV8 A;  4NBD A;  4NBA A;  3AWZ B;  3VMG A;  3VMI A;  1WX5 B;  2AHK B;  3VMH A;  2ZWD B;  3AWY B;  3AWU B;  4NB8 A;  3AX0 B;  3AWX B;  3AWV B;  4NBF A;  1WX2 B;  2DE5 A;  2ZWF B;  2AHL B;  1Z02 A;  1Z01 A;  1WX4 B;  2ZWE B;  3AWW B;  1WXC B;  4NBB A;  2ZMX B;  4NBH A; 
#chains in the Genus database with same CATH homology
 2ZMY B;  2ZWG B;  2ZMZ B;  3AWT B;  3AWS B;  2JV8 A;  3AWZ B;  1WX5 B;  2AHK B;  2ZWD B;  3AWY B;  3AWU B;  3AX0 B;  3AWX B;  3AWV B;  1WX2 B;  2ZWF B;  2AHL B;  1WX4 B;  2ZWE B;  3AWW B;  1WXC B;  2ZMX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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