2ZWGB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 12 hours
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
83
structure length
71
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/metal transport
molecule keywords Tyrosinase
publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
source organism Streptomyces castaneoglobisporus
total genus 16
structure length 71
sequence length 83
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwgB01
2ZMZB 3AWYB 2JV8A 2ZMXB 3AX0B 2AHLB 2ZMYB 3AWUB 1WX2B 3AWTB 3AWSB 3AWWB 2ZWFB 1WXCB 3AWVB 3AWXB 2ZWGB 2ZWEB 1WX5B 2AHKB 2ZWDB 3AWZB 1WX4B
chains in the Genus database with same CATH superfamily
4NBCA 4NB8A 4NBDA 2ZMZB 1Z02A 3GCFA 4NBHA 4NBGA 4NBBA 1WW9A 2DE6A 3AWYB 2JV8A 2DE5A 4NBAA 2ZMXB 3AX0B 2AHLB 2ZMYB 3VMHA 3AWUB 1WX2B 3AWTB 3AWSB 3AWWB 3GKQA 2ZWFB 1WXCB 3AWVB 4NBFA 3AWXB 2ZWGB 4NBEA 2ZWEB 1WX5B 2AHKB 2ZWDB 3VMIA 4NB9A 1Z03A 3VMGA 1Z01A 3AWZB 1WX4B 2DE7A
chains in the Genus database with same CATH topology
2ZMZB 3AWYB 2JV8A 2ZMXB 3AX0B 2AHLB 2ZMYB 3AWUB 1WX2B 3AWTB 3AWSB 3AWWB 2ZWFB 1WXCB 3AWVB 3AWXB 2ZWGB 2ZWEB 1WX5B 2AHKB 2ZWDB 3AWZB 1WX4B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZMZ B;  3AWY B;  2JV8 A;  2ZMX B;  3AX0 B;  2AHL B;  2ZMY B;  3AWU B;  1WX2 B;  3AWT B;  3AWS B;  3AWW B;  2ZWF B;  1WXC B;  3AWV B;  3AWX B;  2ZWG B;  2ZWE B;  1WX5 B;  2AHK B;  2ZWD B;  3AWZ B;  1WX4 B; 
#chains in the Genus database with same CATH topology
 4NBC A;  4NB8 A;  4NBD A;  2ZMZ B;  1Z02 A;  3GCF A;  4NBH A;  4NBG A;  4NBB A;  1WW9 A;  2DE6 A;  3AWY B;  2JV8 A;  2DE5 A;  4NBA A;  2ZMX B;  3AX0 B;  2AHL B;  2ZMY B;  3VMH A;  3AWU B;  1WX2 B;  3AWT B;  3AWS B;  3AWW B;  3GKQ A;  2ZWF B;  1WXC B;  3AWV B;  4NBF A;  3AWX B;  2ZWG B;  4NBE A;  2ZWE B;  1WX5 B;  2AHK B;  2ZWD B;  3VMI A;  4NB9 A;  1Z03 A;  3VMG A;  1Z01 A;  3AWZ B;  1WX4 B;  2DE7 A; 
#chains in the Genus database with same CATH homology
 2ZMZ B;  3AWY B;  2JV8 A;  2ZMX B;  3AX0 B;  2AHL B;  2ZMY B;  3AWU B;  1WX2 B;  3AWT B;  3AWS B;  3AWW B;  2ZWF B;  1WXC B;  3AWV B;  3AWX B;  2ZWG B;  2ZWE B;  1WX5 B;  2AHK B;  2ZWD B;  3AWZ B;  1WX4 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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