2ZWFB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 80 minutes
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
83
structure length
71
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/metal transport
molecule keywords Tyrosinase
publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
source organism Streptomyces castaneoglobisporus
total genus 15
structure length 71
sequence length 83
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwfB01
1WXCB 2ZWEB 3AWYB 2AHLB 1WX4B 3AWWB 1WX5B 2ZMYB 3AWZB 2ZWFB 1WX2B 2AHKB 2ZWGB 2ZMXB 3AWUB 3AX0B 3AWSB 2JV8A 3AWTB 2ZWDB 3AWXB 3AWVB 2ZMZB
chains in the Genus database with same CATH superfamily
1WXCB 2DE7A 2ZWEB 4NBEA 3AWYB 3GCFA 2AHLB 1WX4B 4NB9A 3AWWB 3GKQA 1WX5B 2ZMYB 2DE5A 1Z02A 4NBBA 4NBAA 2DE6A 3AWZB 3VMHA 1Z01A 3VMGA 2ZWFB 1WW9A 4NBGA 4NBHA 3VMIA 1WX2B 2AHKB 2ZWGB 1Z03A 2ZMXB 3AWUB 3AX0B 3AWSB 2JV8A 4NBCA 4NBDA 4NB8A 3AWTB 2ZWDB 3AWXB 3AWVB 4NBFA 2ZMZB
chains in the Genus database with same CATH topology
1WXCB 2ZWEB 3AWYB 2AHLB 1WX4B 3AWWB 1WX5B 2ZMYB 3AWZB 2ZWFB 1WX2B 2AHKB 2ZWGB 2ZMXB 3AWUB 3AX0B 3AWSB 2JV8A 3AWTB 2ZWDB 3AWXB 3AWVB 2ZMZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WXC B;  2ZWE B;  3AWY B;  2AHL B;  1WX4 B;  3AWW B;  1WX5 B;  2ZMY B;  3AWZ B;  2ZWF B;  1WX2 B;  2AHK B;  2ZWG B;  2ZMX B;  3AWU B;  3AX0 B;  3AWS B;  2JV8 A;  3AWT B;  2ZWD B;  3AWX B;  3AWV B;  2ZMZ B; 
#chains in the Genus database with same CATH topology
 1WXC B;  2DE7 A;  2ZWE B;  4NBE A;  3AWY B;  3GCF A;  2AHL B;  1WX4 B;  4NB9 A;  3AWW B;  3GKQ A;  1WX5 B;  2ZMY B;  2DE5 A;  1Z02 A;  4NBB A;  4NBA A;  2DE6 A;  3AWZ B;  3VMH A;  1Z01 A;  3VMG A;  2ZWF B;  1WW9 A;  4NBG A;  4NBH A;  3VMI A;  1WX2 B;  2AHK B;  2ZWG B;  1Z03 A;  2ZMX B;  3AWU B;  3AX0 B;  3AWS B;  2JV8 A;  4NBC A;  4NBD A;  4NB8 A;  3AWT B;  2ZWD B;  3AWX B;  3AWV B;  4NBF A;  2ZMZ B; 
#chains in the Genus database with same CATH homology
 1WXC B;  2ZWE B;  3AWY B;  2AHL B;  1WX4 B;  3AWW B;  1WX5 B;  2ZMY B;  3AWZ B;  2ZWF B;  1WX2 B;  2AHK B;  2ZWG B;  2ZMX B;  3AWU B;  3AX0 B;  3AWS B;  2JV8 A;  3AWT B;  2ZWD B;  3AWX B;  3AWV B;  2ZMZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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