2ZVLA

Crystal structure of pcna in complex with dna polymerase kappa fragment
Total Genus 54
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
255
structure length
245
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNDTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase
molecule keywords Proliferating cell nuclear antigen
publication title Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen
pubmed doi rcsb
source organism Homo sapiens
total genus 54
structure length 245
sequence length 255
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2008-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2zvlA00
2NTIA 2ZVWA 2IX2B 2ZVLA 2IJXA 1SXJF 3U60F 3G65B 3A2FB 1DMLA 2IX2A 3AIXB 5E0VA 5B7OA 3G65A 3U5ZF 3AIXA 3K4XA 3P87A 2AWAA 2AVTA 2HIIA 1U76A 3A1JC 3V60B 3F1WA 4ZTDA 5IY4A 5CFKA 2OD8A 3I2MX 5IXAA 5HACA 2IZOC 3TBLA 2ZVMA 1IZ5A 3P91A 5DAIA 2ZVVA 1B8HA 1RWZA 1PLRA 3P83A 5E0TA 1PLQA 1B77A 3AIZC 3V61B 2HIKC 1T6LA 3IFVA 1GE8A 3A1JB 4L60A 5AUJA 5A6DA 3HI8A 3FDSD 3HSLX 1UD9A 4TR6A 3WGWA 3GGRC 3A1JA 3GPNA 3LX1A 1W60A 2NTIC 1VYJA 1U7BA 1IZ4A 2IZOB 3FDSC 2IO4B 1YYPA 4HK1A 3VKXA 2IX2C 2Z0LA 2IO4A 1RXMA 4CS5A 3G65C 1ISQA 2HIIC 1AXCA 1RXZA 3GPMA 4L6PA 5H0TA 5IWDA 2HIIB 2HIKB 3AIZA 3LX2A 5DA7A 2ZVKA 2HIKA 1VYMA 3GGRB 4YHRA 4RJFA 1UL1A 4D2GA 3GGRA 5E0UA 5JNED 2NTIB 3U61F 1CZDA 3V62B
chains in the Genus database with same CATH superfamily
2NTIA 2ZVWA 2IX2B 2ZVLA 2IJXA 1SXJF 3U60F 3G65B 3A2FB 1DMLA 2IX2A 3AIXB 5E0VA 5B7OA 3G65A 3U5ZF 3AIXA 3K4XA 3P87A 2AWAA 2AVTA 2HIIA 1U76A 3A1JC 3V60B 3F1WA 4ZTDA 5IY4A 5CFKA 2OD8A 3I2MX 5IXAA 5HACA 2IZOC 3TBLA 2ZVMA 1IZ5A 3P91A 5DAIA 2ZVVA 1B8HA 1RWZA 1PLRA 3P83A 5E0TA 1PLQA 1B77A 3AIZC 3V61B 2HIKC 1T6LA 3IFVA 1GE8A 3A1JB 4L60A 5AUJA 5A6DA 3HI8A 3FDSD 3HSLX 1UD9A 4TR6A 3WGWA 3GGRC 3A1JA 3GPNA 3LX1A 1W60A 2NTIC 1VYJA 1U7BA 1IZ4A 2IZOB 3FDSC 2IO4B 1YYPA 4HK1A 3VKXA 2IX2C 2Z0LA 2IO4A 1RXMA 4CS5A 3G65C 1ISQA 2HIIC 1AXCA 1RXZA 3GPMA 4L6PA 5H0TA 5IWDA 2HIIB 2HIKB 3AIZA 3LX2A 5DA7A 2ZVKA 2HIKA 1VYMA 3GGRB 4YHRA 4RJFA 1UL1A 4D2GA 3GGRA 5E0UA 5JNED 2NTIB 3U61F 1CZDA 3V62B
chains in the Genus database with same CATH topology
2NTIA 2ZVWA 2IX2B 2ZVLA 2IJXA 1SXJF 3U60F 3G65B 3A2FB 1DMLA 2IX2A 3AIXB 5E0VA 5B7OA 3G65A 3U5ZF 3AIXA 3K4XA 3P87A 2AWAA 2AVTA 2HIIA 1U76A 3A1JC 3V60B 3F1WA 4ZTDA 5IY4A 5CFKA 2OD8A 3I2MX 5IXAA 5HACA 2IZOC 3TBLA 2ZVMA 1IZ5A 3P91A 5DAIA 2ZVVA 1B8HA 1RWZA 1PLRA 3P83A 5E0TA 1PLQA 1B77A 3AIZC 3V61B 2HIKC 1T6LA 3IFVA 1GE8A 3A1JB 4L60A 5AUJA 5A6DA 3HI8A 3FDSD 3HSLX 1UD9A 4TR6A 3WGWA 3GGRC 3A1JA 3GPNA 3LX1A 1W60A 2NTIC 1VYJA 1U7BA 1IZ4A 2IZOB 3FDSC 2IO4B 1YYPA 4HK1A 3VKXA 2IX2C 2Z0LA 2IO4A 1RXMA 4CS5A 3G65C 1ISQA 2HIIC 1AXCA 1RXZA 3GPMA 4L6PA 5H0TA 5IWDA 2HIIB 2HIKB 3AIZA 3LX2A 5DA7A 2ZVKA 2HIKA 1VYMA 3GGRB 4YHRA 4RJFA 1UL1A 4D2GA 3GGRA 5E0UA 5JNED 2NTIB 3U61F 1CZDA 3V62B
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2NTI A;  2ZVW A;  2IX2 B;  2ZVL A;  2IJX A;  1SXJ F;  3U60 F;  3G65 B;  3A2F B;  1DML A;  2IX2 A;  3AIX B;  5E0V A;  5B7O A;  3G65 A;  3U5Z F;  3AIX A;  3K4X A;  3P87 A;  2AWA A;  2AVT A;  2HII A;  1U76 A;  3A1J C;  3V60 B;  3F1W A;  4ZTD A;  5IY4 A;  5CFK A;  2OD8 A;  3I2M X;  5IXA A;  5HAC A;  2IZO C;  3TBL A;  2ZVM A;  1IZ5 A;  3P91 A;  5DAI A;  2ZVV A;  1B8H A;  1RWZ A;  1PLR A;  3P83 A;  5E0T A;  1PLQ A;  1B77 A;  3AIZ C;  3V61 B;  2HIK C;  1T6L A;  3IFV A;  1GE8 A;  3A1J B;  4L60 A;  5AUJ A;  5A6D A;  3HI8 A;  3FDS D;  3HSL X;  1UD9 A;  4TR6 A;  3WGW A;  3GGR C;  3A1J A;  3GPN A;  3LX1 A;  1W60 A;  2NTI C;  1VYJ A;  1U7B A;  1IZ4 A;  2IZO B;  3FDS C;  2IO4 B;  1YYP A;  4HK1 A;  3VKX A;  2IX2 C;  2Z0L A;  2IO4 A;  1RXM A;  4CS5 A;  3G65 C;  1ISQ A;  2HII C;  1AXC A;  1RXZ A;  3GPM A;  4L6P A;  5H0T A;  5IWD A;  2HII B;  2HIK B;  3AIZ A;  3LX2 A;  5DA7 A;  2ZVK A;  2HIK A;  1VYM A;  3GGR B;  4YHR A;  4RJF A;  1UL1 A;  4D2G A;  3GGR A;  5E0U A;  5JNE D;  2NTI B;  3U61 F;  1CZD A;  3V62 B; 
#chains in the Genus database with same CATH topology
 2NTI A;  2ZVW A;  2IX2 B;  2ZVL A;  2IJX A;  1SXJ F;  3U60 F;  3G65 B;  3A2F B;  1DML A;  2IX2 A;  3AIX B;  5E0V A;  5B7O A;  3G65 A;  3U5Z F;  3AIX A;  3K4X A;  3P87 A;  2AWA A;  2AVT A;  2HII A;  1U76 A;  3A1J C;  3V60 B;  3F1W A;  4ZTD A;  5IY4 A;  5CFK A;  2OD8 A;  3I2M X;  5IXA A;  5HAC A;  2IZO C;  3TBL A;  2ZVM A;  1IZ5 A;  3P91 A;  5DAI A;  2ZVV A;  1B8H A;  1RWZ A;  1PLR A;  3P83 A;  5E0T A;  1PLQ A;  1B77 A;  3AIZ C;  3V61 B;  2HIK C;  1T6L A;  3IFV A;  1GE8 A;  3A1J B;  4L60 A;  5AUJ A;  5A6D A;  3HI8 A;  3FDS D;  3HSL X;  1UD9 A;  4TR6 A;  3WGW A;  3GGR C;  3A1J A;  3GPN A;  3LX1 A;  1W60 A;  2NTI C;  1VYJ A;  1U7B A;  1IZ4 A;  2IZO B;  3FDS C;  2IO4 B;  1YYP A;  4HK1 A;  3VKX A;  2IX2 C;  2Z0L A;  2IO4 A;  1RXM A;  4CS5 A;  3G65 C;  1ISQ A;  2HII C;  1AXC A;  1RXZ A;  3GPM A;  4L6P A;  5H0T A;  5IWD A;  2HII B;  2HIK B;  3AIZ A;  3LX2 A;  5DA7 A;  2ZVK A;  2HIK A;  1VYM A;  3GGR B;  4YHR A;  4RJF A;  1UL1 A;  4D2G A;  3GGR A;  5E0U A;  5JNE D;  2NTI B;  3U61 F;  1CZD A;  3V62 B; 
#chains in the Genus database with same CATH homology
 2NTI A;  2ZVW A;  2IX2 B;  2ZVL A;  2IJX A;  1SXJ F;  3U60 F;  3G65 B;  3A2F B;  1DML A;  2IX2 A;  3AIX B;  5E0V A;  5B7O A;  3G65 A;  3U5Z F;  3AIX A;  3K4X A;  3P87 A;  2AWA A;  2AVT A;  2HII A;  1U76 A;  3A1J C;  3V60 B;  3F1W A;  4ZTD A;  5IY4 A;  5CFK A;  2OD8 A;  3I2M X;  5IXA A;  5HAC A;  2IZO C;  3TBL A;  2ZVM A;  1IZ5 A;  3P91 A;  5DAI A;  2ZVV A;  1B8H A;  1RWZ A;  1PLR A;  3P83 A;  5E0T A;  1PLQ A;  1B77 A;  3AIZ C;  3V61 B;  2HIK C;  1T6L A;  3IFV A;  1GE8 A;  3A1J B;  4L60 A;  5AUJ A;  5A6D A;  3HI8 A;  3FDS D;  3HSL X;  1UD9 A;  4TR6 A;  3WGW A;  3GGR C;  3A1J A;  3GPN A;  3LX1 A;  1W60 A;  2NTI C;  1VYJ A;  1U7B A;  1IZ4 A;  2IZO B;  3FDS C;  2IO4 B;  1YYP A;  4HK1 A;  3VKX A;  2IX2 C;  2Z0L A;  2IO4 A;  1RXM A;  4CS5 A;  3G65 C;  1ISQ A;  2HII C;  1AXC A;  1RXZ A;  3GPM A;  4L6P A;  5H0T A;  5IWD A;  2HII B;  2HIK B;  3AIZ A;  3LX2 A;  5DA7 A;  2ZVK A;  2HIK A;  1VYM A;  3GGR B;  4YHR A;  4RJF A;  1UL1 A;  4D2G A;  3GGR A;  5E0U A;  5JNE D;  2NTI B;  3U61 F;  1CZD A;  3V62 B;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite