4G7LA

Crystal structure of rat heme oxygenase-1 in complex with heme and o2
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
213
structure length
213
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Heme oxygenase 1
publication title Discrimination between CO and O2 in Heme Oxygenase: Comparison of Static Structures and Dynamic Conformation Changes following CO Photolysis
pubmed doi rcsb
source organism Rattus norvegicus
total genus 93
structure length 213
sequence length 213
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2012-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 4g7lA00
4WWZA 2GM7A 2Q32A 1OYLA 5BTQA 1IX4A 1OZEA 1OZWA 1WE1A 1WOVA 1S8CA 3I9UA 4LQXA 4WWJA 1P3UA 1WOWA 1YAFA 1RCWA 1XJZA 1WZDA 1WWMA 1YAKA 4G99A 1IW0A 4MECA 4G98A 2RGZA 1OTVA 2ZVUA 3BJDA 1UBBA 1IRMA 4GPCA 1WZGA 1WNVA 1VGIA 3DDEA 4GPFA 2A6BA 3CZYA 1WNXA 4GOHA 1SK7A 4RAJA 1NI6A 1XK3A 1P3VA 4WX0A 4WD4A 1DVEA 1N3UA 1Z72A 4G7LA 3TGMA 3IBXA 3NO6A 1TWNA 2QCXA 4G7TA 2Z68A 4WMHA 2E7EA 1P3TA 1J2CA 1XK1A 3HOKA 1DVGA 2Q4XA 4G8WA 1OTWA 3B5PA 1V8XA 1OZRA 1TWRA 2A2OA 3HNHA 2DY5A 3HLXA 1WZFA 3RM5A 3MOOA 1IVJA 4G7PA 2RD3A 1XK0A 1T5PA 1N45A 3B5OA 1S13A 1ULXA 4G7UA 3I9TA 4G8PA 4G8UA 1UDDA 2QZCA 1IW1A 1RTWA 1WOXA 3MVUA 3I8RA 1OZLA 3K4FA 4NY7A 1OYKA 4FN6A 1J02A 4GPHA 1TO9B 1XK2A 3OQLA 1J77A 2A2MA 2F2GA 3HMLA 2GM8A 1TYHA 1TO9A 1WNWA 1IX3A 2QPPA
chains in the Genus database with same CATH superfamily
4WWZA 2GM7A 2Q32A 1OYLA 5BTQA 1IX4A 1OZEA 1OZWA 1WE1A 1WOVA 1S8CA 3I9UA 4LQXA 4WWJA 1P3UA 1WOWA 1YAFA 1RCWA 1XJZA 1WZDA 1WWMA 1YAKA 4G99A 1IW0A 4MECA 4G98A 2RGZA 1OTVA 2ZVUA 3BJDA 1UBBA 1IRMA 4GPCA 1WZGA 1WNVA 1VGIA 3DDEA 4GPFA 2A6BA 3CZYA 1WNXA 4GOHA 1SK7A 4RAJA 1NI6A 1XK3A 1P3VA 4WX0A 4WD4A 1DVEA 1N3UA 1Z72A 4G7LA 3TGMA 3IBXA 3NO6A 1TWNA 2QCXA 4G7TA 2Z68A 4WMHA 2E7EA 1P3TA 1J2CA 1XK1A 3HOKA 1DVGA 2Q4XA 4G8WA 1OTWA 3B5PA 1V8XA 1OZRA 1TWRA 2A2OA 3HNHA 2DY5A 3HLXA 1WZFA 3RM5A 3MOOA 1IVJA 4G7PA 2RD3A 1XK0A 1T5PA 1N45A 3B5OA 1S13A 1ULXA 4G7UA 3I9TA 4G8PA 4G8UA 1UDDA 2QZCA 1IW1A 1RTWA 1WOXA 2LCUA 3MVUA 3I8RA 1OZLA 3K4FA 4NY7A 1OYKA 4FN6A 1J02A 4GPHA 1TO9B 1XK2A 3OQLA 1J77A 2A2MA 2F2GA 3HMLA 2GM8A 1TYHA 1TO9A 1WNWA 1IX3A 2QPPA
chains in the Genus database with same CATH topology
4WWZA 2GM7A 2Q32A 1OYLA 5BTQA 1IX4A 1OZEA 1OZWA 1WE1A 1WOVA 1S8CA 3I9UA 4LQXA 4WWJA 1P3UA 1WOWA 1YAFA 1RCWA 1XJZA 1WZDA 1WWMA 1YAKA 4G99A 1IW0A 4MECA 4G98A 2RGZA 1OTVA 2ZVUA 3BJDA 1UBBA 1IRMA 4GPCA 1WZGA 1WNVA 1VGIA 3DDEA 4GPFA 2A6BA 3CZYA 1WNXA 4GOHA 1SK7A 4RAJA 1NI6A 1XK3A 1P3VA 4WX0A 4WD4A 1DVEA 1N3UA 1Z72A 4G7LA 3TGMA 3IBXA 3NO6A 1TWNA 2QCXA 4G7TA 2Z68A 4WMHA 2E7EA 1P3TA 1J2CA 1XK1A 3HOKA 1DVGA 2Q4XA 4G8WA 1OTWA 3B5PA 1V8XA 1OZRA 1TWRA 2A2OA 3HNHA 2DY5A 3HLXA 1WZFA 3RM5A 3MOOA 1IVJA 4G7PA 2RD3A 1XK0A 1T5PA 1N45A 3B5OA 1S13A 1ULXA 4G7UA 3I9TA 4G8PA 4G8UA 1UDDA 2QZCA 1IW1A 1RTWA 1WOXA 3MVUA 3I8RA 1OZLA 3K4FA 4NY7A 1OYKA 4FN6A 1J02A 4GPHA 1TO9B 1XK2A 3OQLA 1J77A 2A2MA 2F2GA 3HMLA 2GM8A 1TYHA 1TO9A 1WNWA 1IX3A 2QPPA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4WWZ A;  2GM7 A;  2Q32 A;  1OYL A;  5BTQ A;  1IX4 A;  1OZE A;  1OZW A;  1WE1 A;  1WOV A;  1S8C A;  3I9U A;  4LQX A;  4WWJ A;  1P3U A;  1WOW A;  1YAF A;  1RCW A;  1XJZ A;  1WZD A;  1WWM A;  1YAK A;  4G99 A;  1IW0 A;  4MEC A;  4G98 A;  2RGZ A;  1OTV A;  2ZVU A;  3BJD A;  1UBB A;  1IRM A;  4GPC A;  1WZG A;  1WNV A;  1VGI A;  3DDE A;  4GPF A;  2A6B A;  3CZY A;  1WNX A;  4GOH A;  1SK7 A;  4RAJ A;  1NI6 A;  1XK3 A;  1P3V A;  4WX0 A;  4WD4 A;  1DVE A;  1N3U A;  1Z72 A;  4G7L A;  3TGM A;  3IBX A;  3NO6 A;  1TWN A;  2QCX A;  4G7T A;  2Z68 A;  4WMH A;  2E7E A;  1P3T A;  1J2C A;  1XK1 A;  3HOK A;  1DVG A;  2Q4X A;  4G8W A;  1OTW A;  3B5P A;  1V8X A;  1OZR A;  1TWR A;  2A2O A;  3HNH A;  2DY5 A;  3HLX A;  1WZF A;  3RM5 A;  3MOO A;  1IVJ A;  4G7P A;  2RD3 A;  1XK0 A;  1T5P A;  1N45 A;  3B5O A;  1S13 A;  1ULX A;  4G7U A;  3I9T A;  4G8P A;  4G8U A;  1UDD A;  2QZC A;  1IW1 A;  1RTW A;  1WOX A;  3MVU A;  3I8R A;  1OZL A;  3K4F A;  4NY7 A;  1OYK A;  4FN6 A;  1J02 A;  4GPH A;  1TO9 B;  1XK2 A;  3OQL A;  1J77 A;  2A2M A;  2F2G A;  3HML A;  2GM8 A;  1TYH A;  1TO9 A;  1WNW A;  1IX3 A;  2QPP A; 
#chains in the Genus database with same CATH topology
 4WWZ A;  2GM7 A;  2Q32 A;  1OYL A;  5BTQ A;  1IX4 A;  1OZE A;  1OZW A;  1WE1 A;  1WOV A;  1S8C A;  3I9U A;  4LQX A;  4WWJ A;  1P3U A;  1WOW A;  1YAF A;  1RCW A;  1XJZ A;  1WZD A;  1WWM A;  1YAK A;  4G99 A;  1IW0 A;  4MEC A;  4G98 A;  2RGZ A;  1OTV A;  2ZVU A;  3BJD A;  1UBB A;  1IRM A;  4GPC A;  1WZG A;  1WNV A;  1VGI A;  3DDE A;  4GPF A;  2A6B A;  3CZY A;  1WNX A;  4GOH A;  1SK7 A;  4RAJ A;  1NI6 A;  1XK3 A;  1P3V A;  4WX0 A;  4WD4 A;  1DVE A;  1N3U A;  1Z72 A;  4G7L A;  3TGM A;  3IBX A;  3NO6 A;  1TWN A;  2QCX A;  4G7T A;  2Z68 A;  4WMH A;  2E7E A;  1P3T A;  1J2C A;  1XK1 A;  3HOK A;  1DVG A;  2Q4X A;  4G8W A;  1OTW A;  3B5P A;  1V8X A;  1OZR A;  1TWR A;  2A2O A;  3HNH A;  2DY5 A;  3HLX A;  1WZF A;  3RM5 A;  3MOO A;  1IVJ A;  4G7P A;  2RD3 A;  1XK0 A;  1T5P A;  1N45 A;  3B5O A;  1S13 A;  1ULX A;  4G7U A;  3I9T A;  4G8P A;  4G8U A;  1UDD A;  2QZC A;  1IW1 A;  1RTW A;  1WOX A;  2LCU A;  3MVU A;  3I8R A;  1OZL A;  3K4F A;  4NY7 A;  1OYK A;  4FN6 A;  1J02 A;  4GPH A;  1TO9 B;  1XK2 A;  3OQL A;  1J77 A;  2A2M A;  2F2G A;  3HML A;  2GM8 A;  1TYH A;  1TO9 A;  1WNW A;  1IX3 A;  2QPP A; 
#chains in the Genus database with same CATH homology
 4WWZ A;  2GM7 A;  2Q32 A;  1OYL A;  5BTQ A;  1IX4 A;  1OZE A;  1OZW A;  1WE1 A;  1WOV A;  1S8C A;  3I9U A;  4LQX A;  4WWJ A;  1P3U A;  1WOW A;  1YAF A;  1RCW A;  1XJZ A;  1WZD A;  1WWM A;  1YAK A;  4G99 A;  1IW0 A;  4MEC A;  4G98 A;  2RGZ A;  1OTV A;  2ZVU A;  3BJD A;  1UBB A;  1IRM A;  4GPC A;  1WZG A;  1WNV A;  1VGI A;  3DDE A;  4GPF A;  2A6B A;  3CZY A;  1WNX A;  4GOH A;  1SK7 A;  4RAJ A;  1NI6 A;  1XK3 A;  1P3V A;  4WX0 A;  4WD4 A;  1DVE A;  1N3U A;  1Z72 A;  4G7L A;  3TGM A;  3IBX A;  3NO6 A;  1TWN A;  2QCX A;  4G7T A;  2Z68 A;  4WMH A;  2E7E A;  1P3T A;  1J2C A;  1XK1 A;  3HOK A;  1DVG A;  2Q4X A;  4G8W A;  1OTW A;  3B5P A;  1V8X A;  1OZR A;  1TWR A;  2A2O A;  3HNH A;  2DY5 A;  3HLX A;  1WZF A;  3RM5 A;  3MOO A;  1IVJ A;  4G7P A;  2RD3 A;  1XK0 A;  1T5P A;  1N45 A;  3B5O A;  1S13 A;  1ULX A;  4G7U A;  3I9T A;  4G8P A;  4G8U A;  1UDD A;  2QZC A;  1IW1 A;  1RTW A;  1WOX A;  3MVU A;  3I8R A;  1OZL A;  3K4F A;  4NY7 A;  1OYK A;  4FN6 A;  1J02 A;  4GPH A;  1TO9 B;  1XK2 A;  3OQL A;  1J77 A;  2A2M A;  2F2G A;  3HML A;  2GM8 A;  1TYH A;  1TO9 A;  1WNW A;  1IX3 A;  2QPP A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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