4D2GA

Crystal structure of human pcna in complex with p15 peptide
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
258
structure length
258
Chain Sequence
GPHMFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Transcription
molecule keywords PROLIFERATING CELL NUCLEAR ANTIGEN
publication title Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
pubmed doi rcsb
source organism Homo sapiens
total genus 60
structure length 258
sequence length 258
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2014-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 4d2gA00
5IXAA 1UL1A 3A1JC 3I2MX 4RJFA 5H0TA 1YYPA 4HK1A 3K4XA 5CFKA 1VYMA 3A1JB 1VYJA 3LX2A 3V61B 3HSLX 3GPMA 3A1JA 1RXZA 2OD8A 2AWAA 5DA7A 2ZVVA 1UD9A 3V62B 3P83A 3A2FB 3F1WA 1U7BA 3G65C 5E0UA 1RXMA 2NTIC 2IZOC 2IJXA 4L60A 3AIXB 3G65B 1AXCA 5DAIA 2NTIB 1W60A 2IO4B 4CS5A 2IZOB 1T6LA 3IFVA 3AIXA 2HIKC 3G65A 3VKXA 3FDSD 3P91A 2NTIA 2ZVMA 2IO4A 4TR6A 4D2GA 2HIKB 3AIZC 1B77A 1PLQA 5B7OA 3TBLA 3U61F 1GE8A 1CZDA 5HACA 3GGRC 2HIKA 3U5ZF 5E0VA 1RWZA 1B8HA 3GGRB 2HIIC 3AIZA 3V60B 1ISQA 1DMLA 4ZTDA 5IWDA 1IZ4A 4L6PA 3HI8A 2IX2C 2HIIB 3GGRA 2ZVKA 1IZ5A 4YHRA 3P87A 1PLRA 2AVTA 2IX2B 3U60F 2HIIA 1U76A 3FDSC 5E0TA 1SXJF 2IX2A 3GPNA 5IY4A 2ZVWA 2ZVLA 2Z0LA 3LX1A 5A6DA 5AUJA 3WGWA 5JNED
chains in the Genus database with same CATH superfamily
5IXAA 1UL1A 3A1JC 3I2MX 4RJFA 5H0TA 1YYPA 4HK1A 3K4XA 5CFKA 1VYMA 3A1JB 1VYJA 3LX2A 3V61B 3HSLX 3GPMA 3A1JA 1RXZA 2OD8A 2AWAA 5DA7A 2ZVVA 1UD9A 3V62B 3P83A 3A2FB 3F1WA 1U7BA 3G65C 5E0UA 1RXMA 2NTIC 2IZOC 2IJXA 4L60A 3AIXB 3G65B 1AXCA 5DAIA 2NTIB 1W60A 2IO4B 4CS5A 2IZOB 1T6LA 3IFVA 3AIXA 2HIKC 3G65A 3VKXA 3FDSD 3P91A 2NTIA 2ZVMA 2IO4A 4TR6A 4D2GA 2HIKB 3AIZC 1B77A 1PLQA 5B7OA 3TBLA 3U61F 1GE8A 1CZDA 5HACA 3GGRC 2HIKA 3U5ZF 5E0VA 1RWZA 1B8HA 3GGRB 2HIIC 3AIZA 3V60B 1ISQA 1DMLA 4ZTDA 5IWDA 1IZ4A 4L6PA 3HI8A 2IX2C 2HIIB 3GGRA 2ZVKA 1IZ5A 4YHRA 3P87A 1PLRA 2AVTA 2IX2B 3U60F 2HIIA 1U76A 3FDSC 5E0TA 1SXJF 2IX2A 3GPNA 5IY4A 2ZVWA 2ZVLA 2Z0LA 3LX1A 5A6DA 5AUJA 3WGWA 5JNED
chains in the Genus database with same CATH topology
5IXAA 1UL1A 3A1JC 3I2MX 4RJFA 5H0TA 1YYPA 4HK1A 3K4XA 5CFKA 1VYMA 3A1JB 1VYJA 3LX2A 3V61B 3HSLX 3GPMA 3A1JA 1RXZA 2OD8A 2AWAA 5DA7A 2ZVVA 1UD9A 3V62B 3P83A 3A2FB 3F1WA 1U7BA 3G65C 5E0UA 1RXMA 2NTIC 2IZOC 2IJXA 4L60A 3AIXB 3G65B 1AXCA 5DAIA 2NTIB 1W60A 2IO4B 4CS5A 2IZOB 1T6LA 3IFVA 3AIXA 2HIKC 3G65A 3VKXA 3FDSD 3P91A 2NTIA 2ZVMA 2IO4A 4TR6A 4D2GA 2HIKB 3AIZC 1B77A 1PLQA 5B7OA 3TBLA 3U61F 1GE8A 1CZDA 5HACA 3GGRC 2HIKA 3U5ZF 5E0VA 1RWZA 1B8HA 3GGRB 2HIIC 3AIZA 3V60B 1ISQA 1DMLA 4ZTDA 5IWDA 1IZ4A 4L6PA 3HI8A 2IX2C 2HIIB 3GGRA 2ZVKA 1IZ5A 4YHRA 3P87A 1PLRA 2AVTA 2IX2B 3U60F 2HIIA 1U76A 3FDSC 5E0TA 1SXJF 2IX2A 3GPNA 5IY4A 2ZVWA 2ZVLA 2Z0LA 3LX1A 5A6DA 5AUJA 3WGWA 5JNED
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 5IXA A;  1UL1 A;  3A1J C;  3I2M X;  4RJF A;  5H0T A;  1YYP A;  4HK1 A;  3K4X A;  5CFK A;  1VYM A;  3A1J B;  1VYJ A;  3LX2 A;  3V61 B;  3HSL X;  3GPM A;  3A1J A;  1RXZ A;  2OD8 A;  2AWA A;  5DA7 A;  2ZVV A;  1UD9 A;  3V62 B;  3P83 A;  3A2F B;  3F1W A;  1U7B A;  3G65 C;  5E0U A;  1RXM A;  2NTI C;  2IZO C;  2IJX A;  4L60 A;  3AIX B;  3G65 B;  1AXC A;  5DAI A;  2NTI B;  1W60 A;  2IO4 B;  4CS5 A;  2IZO B;  1T6L A;  3IFV A;  3AIX A;  2HIK C;  3G65 A;  3VKX A;  3FDS D;  3P91 A;  2NTI A;  2ZVM A;  2IO4 A;  4TR6 A;  4D2G A;  2HIK B;  3AIZ C;  1B77 A;  1PLQ A;  5B7O A;  3TBL A;  3U61 F;  1GE8 A;  1CZD A;  5HAC A;  3GGR C;  2HIK A;  3U5Z F;  5E0V A;  1RWZ A;  1B8H A;  3GGR B;  2HII C;  3AIZ A;  3V60 B;  1ISQ A;  1DML A;  4ZTD A;  5IWD A;  1IZ4 A;  4L6P A;  3HI8 A;  2IX2 C;  2HII B;  3GGR A;  2ZVK A;  1IZ5 A;  4YHR A;  3P87 A;  1PLR A;  2AVT A;  2IX2 B;  3U60 F;  2HII A;  1U76 A;  3FDS C;  5E0T A;  1SXJ F;  2IX2 A;  3GPN A;  5IY4 A;  2ZVW A;  2ZVL A;  2Z0L A;  3LX1 A;  5A6D A;  5AUJ A;  3WGW A;  5JNE D; 
#chains in the Genus database with same CATH topology
 5IXA A;  1UL1 A;  3A1J C;  3I2M X;  4RJF A;  5H0T A;  1YYP A;  4HK1 A;  3K4X A;  5CFK A;  1VYM A;  3A1J B;  1VYJ A;  3LX2 A;  3V61 B;  3HSL X;  3GPM A;  3A1J A;  1RXZ A;  2OD8 A;  2AWA A;  5DA7 A;  2ZVV A;  1UD9 A;  3V62 B;  3P83 A;  3A2F B;  3F1W A;  1U7B A;  3G65 C;  5E0U A;  1RXM A;  2NTI C;  2IZO C;  2IJX A;  4L60 A;  3AIX B;  3G65 B;  1AXC A;  5DAI A;  2NTI B;  1W60 A;  2IO4 B;  4CS5 A;  2IZO B;  1T6L A;  3IFV A;  3AIX A;  2HIK C;  3G65 A;  3VKX A;  3FDS D;  3P91 A;  2NTI A;  2ZVM A;  2IO4 A;  4TR6 A;  4D2G A;  2HIK B;  3AIZ C;  1B77 A;  1PLQ A;  5B7O A;  3TBL A;  3U61 F;  1GE8 A;  1CZD A;  5HAC A;  3GGR C;  2HIK A;  3U5Z F;  5E0V A;  1RWZ A;  1B8H A;  3GGR B;  2HII C;  3AIZ A;  3V60 B;  1ISQ A;  1DML A;  4ZTD A;  5IWD A;  1IZ4 A;  4L6P A;  3HI8 A;  2IX2 C;  2HII B;  3GGR A;  2ZVK A;  1IZ5 A;  4YHR A;  3P87 A;  1PLR A;  2AVT A;  2IX2 B;  3U60 F;  2HII A;  1U76 A;  3FDS C;  5E0T A;  1SXJ F;  2IX2 A;  3GPN A;  5IY4 A;  2ZVW A;  2ZVL A;  2Z0L A;  3LX1 A;  5A6D A;  5AUJ A;  3WGW A;  5JNE D; 
#chains in the Genus database with same CATH homology
 5IXA A;  1UL1 A;  3A1J C;  3I2M X;  4RJF A;  5H0T A;  1YYP A;  4HK1 A;  3K4X A;  5CFK A;  1VYM A;  3A1J B;  1VYJ A;  3LX2 A;  3V61 B;  3HSL X;  3GPM A;  3A1J A;  1RXZ A;  2OD8 A;  2AWA A;  5DA7 A;  2ZVV A;  1UD9 A;  3V62 B;  3P83 A;  3A2F B;  3F1W A;  1U7B A;  3G65 C;  5E0U A;  1RXM A;  2NTI C;  2IZO C;  2IJX A;  4L60 A;  3AIX B;  3G65 B;  1AXC A;  5DAI A;  2NTI B;  1W60 A;  2IO4 B;  4CS5 A;  2IZO B;  1T6L A;  3IFV A;  3AIX A;  2HIK C;  3G65 A;  3VKX A;  3FDS D;  3P91 A;  2NTI A;  2ZVM A;  2IO4 A;  4TR6 A;  4D2G A;  2HIK B;  3AIZ C;  1B77 A;  1PLQ A;  5B7O A;  3TBL A;  3U61 F;  1GE8 A;  1CZD A;  5HAC A;  3GGR C;  2HIK A;  3U5Z F;  5E0V A;  1RWZ A;  1B8H A;  3GGR B;  2HII C;  3AIZ A;  3V60 B;  1ISQ A;  1DML A;  4ZTD A;  5IWD A;  1IZ4 A;  4L6P A;  3HI8 A;  2IX2 C;  2HII B;  3GGR A;  2ZVK A;  1IZ5 A;  4YHR A;  3P87 A;  1PLR A;  2AVT A;  2IX2 B;  3U60 F;  2HII A;  1U76 A;  3FDS C;  5E0T A;  1SXJ F;  2IX2 A;  3GPN A;  5IY4 A;  2ZVW A;  2ZVL A;  2Z0L A;  3LX1 A;  5A6D A;  5AUJ A;  3WGW A;  5JNE D;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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