|
95
|
287
|
7dp4A |
Crystal structure of wild type brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate |
|
99
|
285
|
7dp6A |
Crystal structure of mutant v45t brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate |
|
95
|
287
|
7dp5A |
Crystal structure of mutant v45a brugia malayi thymidylate synthase complexed with 2'-deoxyuridine monophosphate and methotrexate |
|
85
|
275
|
7ta9A |
Crystal structure of thymidylate synthase from acinetobacter baumannii |
|
154
|
605
|
7ctzA |
Wild-type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with fragment 148, nadph, and dump |
|
185
|
606
|
7fgwA |
Toxoplasma gondii dihydrofolate reductase thymidylate synthase (tgdhfr-ts) complexed with pyrimethamine, nadph and dump |
|
173
|
605
|
7fgyA |
Toxoplasma gondii dihydrofolate reductase thymidylate synthase (tgdhfr-ts) complexed with p40, nadph and dump |
|
179
|
606
|
7fgxA |
Toxoplasma gondii dihydrofolate reductase thymidylate synthase (tgdhfr-ts) complexed with p39, nadph and dump |
|
171
|
605
|
8jfcA |
V1/s quadruple mutant plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 6 (b21591), nadph and dump |
|
169
|
604
|
8jfbA |
V1/s quadruple mutant plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 4 (b21588), nadph and dump |
|
173
|
604
|
8jfdA |
V1/s quadruple mutant plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 8 (b21594), nadph and dump |
|
137
|
494
|
8daeA |
Arabidopsis thaliana bifunctional dihydrofolate reductase-thymidylate synthase |
|
96
|
283
|
7xyjA |
Structure of wssv thymidylate synthase in complex with dump |
|
98
|
290
|
7xykA |
Structure of wssv thymidylate synthase in complex with dump and raltitrexed |
|
163
|
608
|
7f3zA |
Double mutant plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts-k1, c59r+s108n) complexed with trimethoprim (top), nadph and dump |
|
167
|
608
|
7f3yA |
Wild-type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with methotrexate (mtx), nadph and dump |
|
88
|
287
|
6zxoF |
Crystal structure of his-tagged human thymidylate synthase (ht-hts) in complex with fdump and raltitrexed (tomudex) |
|
90
|
288
|
6zxoA |
Crystal structure of his-tagged human thymidylate synthase (ht-hts) in complex with fdump and raltitrexed (tomudex) |
|
82
|
263
|
7jx1A |
E. coli tsase complex with a bi-substrate reaction intermediate analog |
|
82
|
263
|
7jxfA |
E. coli tsase complex with a bi-substrate reaction intermediate diastereomer analog |
|
139
|
602
|
7ctyA |
Wild type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts), fragment 263, nadp+, dump |
|
90
|
279
|
6y08A |
Mouse thymidylate synthase cocrystallized with dump and soaked in sulfamethoxazole |
|
156
|
602
|
6lhiA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with c466 (compound 42) and nadph |
|
167
|
602
|
6lezA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 46 and nadph |
|
150
|
602
|
6lh9A |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 46 and nadph |
|
165
|
603
|
6leuA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 42 and nadph |
|
170
|
608
|
6lhjA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with c452 (compound 16) and nadph |
|
168
|
602
|
6levA |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with compound 46 and nadph |
|
103
|
294
|
7cc8A |
Crystal structure of white spot syndrome virus thymidylate synthase - apo form |
|
94
|
289
|
7ccaA |
Crystal structure of white spot syndrome virus thymidylate synthase - ternary complex with methotrexate and dump |
|
92
|
289
|
6k7sA |
Crystal structure of thymidylate synthase from shrimp |
|
92
|
285
|
6k7qA |
Crystal structure of thymidylate synthase from shrimp |
|
91
|
280
|
6k7rA |
Crystal structure of thymidylate synthase from shrimp |
|
109
|
315
|
6qxsB |
Crystal structure of enteroccocus faecalis thymidylate synthase (efts) in complex with fdump |
|
165
|
564
|
6n1sA |
Toxoplasma gondii ts-dhfr in complex with selective inhibitor 29 |
|
144
|
564
|
6n1tA |
Toxoplasma gondii ts-dhfr in complex with selective inhibitor 3 |
|
97
|
287
|
6f6zA |
Mouse thymidylate synthase cocrystallized with n(4)ohdcmp and soaked in methylenetetrahydrofolate |
|
87
|
288
|
6r2eA |
Crystal structure of the human thymidylate synthase (hts) interface variant q62r |
|
86
|
313
|
6qxsA |
Crystal structure of enteroccocus faecalis thymidylate synthase (efts) in complex with fdump |
|
88
|
288
|
6r2eE |
Crystal structure of the human thymidylate synthase (hts) interface variant q62r |
|
88
|
289
|
6qyqB |
Crystal structure of human thymidylate synthase (hts) variant r175c |
|
105
|
315
|
6qyaB |
Crystal structure of enteroccocus faecalis thymidylate synthase (efts) in complex with dump |
|
90
|
289
|
6qyqA |
Crystal structure of human thymidylate synthase (hts) variant r175c |
|
82
|
314
|
6qyaA |
Crystal structure of enteroccocus faecalis thymidylate synthase (efts) in complex with dump |
|
93
|
287
|
6qxhA |
Crystal structure of his-tag human thymidylate synthase (ht-hts) in complex with dump |
|
90
|
289
|
6qyqC |
Crystal structure of human thymidylate synthase (hts) variant r175c |
|
93
|
287
|
6qxgA |
Crystal structure of his-tag human thymidylate synthase (ht-hts) in complex with fdump |
|
85
|
290
|
6qyqD |
Crystal structure of human thymidylate synthase (hts) variant r175c |
|
169
|
608
|
3um8A |
Wild-type plasmodium falciparum dhfr-ts complexed with cycloguanil and nadph |
|
96
|
290
|
5m4zA |
Crystal structure of the complex of t.spiralis thymidylate synthase with n(4)-hydroxy-2'-deoxycytidine-5'-monophosphate, crystallized in the presence of n(5,10)-methylenetetrahydrofolate |
