79
|
268
|
8w34A |
Hiv-1 intasome core assembled with wild-type integrase, 1f |
75
|
266
|
8w2rA |
Hiv-1 p5-in intasome core |
74
|
268
|
8w09A |
Hiv-1 wild-type intasome core |
44
|
153
|
8s9qA |
Hiv-1 integrase catalytic core domain (ccd) f185h mutant complexed with stp03-0404 |
41
|
150
|
7l23A |
Hiv integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid |
42
|
150
|
7l2yAAA |
Hiv integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid |
42
|
153
|
7l1pA |
Hiv integrase core domain (in) in complex with dimer-spanning ligand |
42
|
154
|
7lqpA |
Rapid development of potent inhibitors of the hiv integrase-ledgf interaction by fragment-linking using off-rate screening |
8
|
56
|
8buvA |
Hiv-1 integrase catalytic core domain and c-terminal domain in complex with allosteric integrase inhibitor ledgin 3 |
68
|
275
|
7zppA |
Cryo-em structure of the mvv csc intasome at 4.5a resolution |
61
|
276
|
7u32A |
Mvv cleaved synaptic complex (csc) intasome at 3.4 a resolution |
52
|
152
|
7uoqA |
Crystal structure of hiv-1 integrase complexed with (2s)-2-(tert-butoxy)-2-(5-{2-[(2-chloro-6-m ethylphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-6-yl}-4- (4,4-dimethylpiperidin-1-yl)-2-methylpyridin-3-yl)acetic acid |
49
|
157
|
7t9hA |
Hiv integrase in complex with compound-15 |
53
|
152
|
7t9oA |
Hiv integrase in complex with compound-25 |
8
|
47
|
8cbtA |
Hiv-1 integrase catalytic core domain and c-terminal domain in complex with allosteric integrase inhibitor mut872 |
59
|
155
|
8wf7A |
The crystal structure of integrase from biortus |
180
|
762
|
8ftiA |
Cryo-em structure of the cas13bt3-crrna-target rna ternary complex in activated state |
47
|
153
|
8d3sA |
Hiv-1 integrase catalytic core domain f185h mutant complexed with bkc-110 |
7
|
53
|
8cbrA |
Hiv-1 integrase catalytic core domain and c-terminal domain in complex with allosteric integrase inhibitor bdm-2 |
8
|
53
|
8cbsA |
Hiv-1 integrase catalytic core domain and c-terminal domain in complex with allosteric integrase inhibitor mut871 |
46
|
152
|
8bv2A |
Biological and structural analysis of new potent integrase-ledgf allosteric hiv-1 inhibitors |
7
|
52
|
8cbvA |
Hiv-1 integrase catalytic core domain and c-terminal domain in complex with allosteric integrase inhibitor mut916 |
8
|
53
|
8cbuA |
Hiv-1 integrase catalytic core domain and c-terminal domain in complex with allosteric integrase inhibitor mut884 |
36
|
269
|
8e14A |
Cryo-em structure of rous sarcoma virus strand transfer complex |
44
|
152
|
7ue1A |
Hiv-1 integrase catalytic core domain mutant (kgd) in complex with inhibitor grl-142 |
46
|
154
|
8ct5A |
Catalytic core domain of hiv-1 integrase (f185k) |
50
|
156
|
8ct7A |
Catalytic core domain of hiv-1 integrase (f185k) bound with bi-224436 |
47
|
152
|
8ctaA |
Minimal 2:2 ternary complex between bi-224436 bound hiv-1 integrase catalytic core domain dimer and carboxy terminal domains |
6
|
51
|
8ctaC |
Minimal 2:2 ternary complex between bi-224436 bound hiv-1 integrase catalytic core domain dimer and carboxy terminal domains |
10
|
57
|
8a1qA |
Hiv-1 integrase catalytic core domain and c-terminal domain in complex with allosteric integrase inhibitor stp0404 (pirmitegravir) |
9
|
52
|
8a1pA |
Hiv-1 integrase catalytic core domain and c-terminal domain in complex with allosteric integrase inhibitor bi-d |
52
|
152
|
7u2uA |
Crystal structure of hiv-1 integrase complexed with compound-2a aka (2s)-2-(tert-butoxy)-2-[7-(4,4-dimethylpipe ridin-1-yl)-8-{4-[2-(4-fluorophenyl)ethoxy]phenyl}-2,5-dim ethylimidazo[1,2-a]pyridin-6-yl]acetic acid |
42
|
152
|
7siaA |
Hiv integrase core domain in complex with inhibitor 2-[2-(2-{3-[(4-{2-[(3-{2-[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}phenyl)formamido]ethyl}piperazin-1-yl)methyl]phenyl}ethynyl)-5-methyl-1-benzofuran-3-yl]acetic acid |
60
|
264
|
7ut1A |
Higher-order assembly of multiple mmtv strand transfer complex intasomes |
63
|
265
|
7usfA |
Mouse mammary tumor virus strand transfer complex intasome |
45
|
152
|
7rq0A |
Hiv integrase core domain in complex with 2-{2-[2-(3-{[4-(2-{[(3-{2-[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}phenyl)methyl]amino}ethyl)piperazin-1-yl]methyl}phenyl)ethynyl]-5-methyl-1-benzofuran-3-yl}acetic acid |
44
|
151
|
7ke0A |
Hiv-1 integrase catalytic core domain complexed with allosteric inhibitor stp03-0404 |
56
|
278
|
7ouhA |
Structure of the stlv intasome:b56 complex bound to the strand-transfer inhibitor bictegravir |
52
|
278
|
7ougA |
Stlv-1 intasome:b56 in complex with the strand-transfer inhibitor raltegravir |
81
|
307
|
7ougC |
Stlv-1 intasome:b56 in complex with the strand-transfer inhibitor raltegravir |
78
|
307
|
7ouhC |
Structure of the stlv intasome:b56 complex bound to the strand-transfer inhibitor bictegravir |
59
|
278
|
7oufA |
Structure of the stlv intasome:b56 complex bound to the strand-transfer inhibitor xz450 |
84
|
307
|
7oufC |
Structure of the stlv intasome:b56 complex bound to the strand-transfer inhibitor xz450 |
23
|
96
|
7jyzB |
Solution nmr structure and dynamics of human brd3 et in complex with mlv in ctd |
10
|
89
|
7jyzA |
Solution nmr structure and dynamics of human brd3 et in complex with mlv in ctd |
47
|
152
|
6wc8A |
Hiv integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid |
41
|
150
|
6we7A |
Hiv integrase core domain in complex with inhibitor 3-methyl-2-{5-methyl-2-[2-(thiophen-2-yl)ethynyl]-1- benzofuran-3-yl}butanoic acid |
104
|
367
|
7advA |
Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the insti xz447 (compound 6v) |
100
|
367
|
7aduA |
Crystal structure of the prototype foamy virus (pfv) intasome in complex with magnesium and the insti xz440 (compound 5j) |
66
|
269
|
7ku7A |
Cryo-em structure of rous sarcoma virus cleaved synaptic complex (csc) with hiv-1 integrase strand transfer inhibitor mk-2048. cluster identified by 3-dimensional variability analysis in cryosparc. |