Found 412 chains in Genus chains table. Displaying 1 - 50. Applied filters: Proteins

Search results query: DHFR_1

Total Genus Sequence Length pdb Title
135 517 6wepA Crystal structure of ts-dhfr from cryptosporidium hominis with apo-ts site
43 159 6vs9A Mycobacterium tuberculosis dihydrofolate reductase in complex with 3-(piperidin-1-ylmethyl)benzoic acid(fragment 11)
42 159 6vsfA Mycobacterium tuberculosis dihydrofolate reductase in complex with 4-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-4-oxobutanoic acid(fragment 16)
38 159 6vv6A Mycobacterium tuberculosis dihydrofolate reductase in complex with jeb113
45 160 6vvbA Mycobacterium tuberculosis dihydrofolate reductase in complex with 6-methyl-5-(4-phenylthiazol-2-yl)-2- (trifluoromethyl)nicotinic acid (fragment 10)
40 159 6vs6A Mycobacterium tuberculosis dihydrofolate reductase in complex with 3-(furan-2-yl)-1-methyl-1h-pyrazole-5-carboxylic acid (fragment 2)
40 159 6vv7A Mycobacterium tuberculosis dihydrofolate reductase in complex with jeb136
39 159 6vsdA Mycobacterium tuberculosis dihydrofolate reductase in complex with 3-((thiophen-2-ylthio)methyl)benzoic acid (fragment 13)
39 159 6vv9A Mycobacterium tuberculosis dihydrofolate reductase in complex with jeb300
42 159 6vsgA Mycobacterium tuberculosis dihydrofolate reductase in complex with 4-(trifluoromethyl)benzene-1,2-diamine(fragment 17)
40 159 6vseA Mycobacterium tuberculosis dihydrofolate reductase in complex with 3-(phenoxymethyl)benzoic acid(fragment 14)
41 159 6vs5A Mycobacterium tuberculosis dihydrofolate reductase in complex with 5-methyl-1-phenyl-1h-pyrazole-4-carboxylic acid (fragment 1)
39 159 6vv8A Mycobacterium tuberculosis dihydrofolate reductase in complex with jeb285
41 159 6vs8A Mycobacterium tuberculosis dihydrofolate reductase in complex with ethyl 2-methyl thiazole-4-carboxylate(fragment 3)
41 162 6prbA S. aureus dihydrofolate reductase co-crystallized with cyclopropyl-dimethyoxydihydropthalazine inhibitor and nadp(h)
41 162 6pr8A S. aureus dihydrofoate reductase co-crystallized with 3,5-dimethylphenyl-dihydropthalazine inhibitor and nadp(h)
42 162 6pr6A S. aureus dihydrofolate reductase co-crystallized with para-tolyl-dihydropthalazine inhibitor and nadp(h)
42 163 6praA S. aureus dihydrofolate reductase with nadp(h) and empty folate pocket
44 162 6pr9A S. aureus dihydrofolate reductase co-crystallized with 1-ethylpropyl-dihydropthalazine inhibitor and nadp(h)
42 162 6prdA S. aureus dihydrofolate reductase co-crystallized with para-methoxyphenyl-dimethyoxydihydropthalazine inhibitor and nadp(h)
41 163 6pr7A S. aureus dihydrofolate reductase co-crystallized with benzyl-dihydropthalazine inhibitor and nadp(h)
42 157 5ispX Staphylococcus aureus f98y dihydrofolate reductase mutant complexed with beta-nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106)
43 162 6cw7A E. coli dhfr product complex with (6s)-5,6,7,8-tetrahydrofolate
42 161 6cyvA E. coli dhfr ternary complex with nadp and dihydrofolate
37 159 6cqaA E. coli dhfr complex with inhibitor ampqd
45 165 6cxkA E. coli dhfr substrate complex with dihydrofolate
57 186 6a7eA Human dihydrofolate reductase complexed with nadph and bt2
45 162 6mt8A E. coli dhfr complex modeled with two ligand states
45 162 6mr9A E. coli dhfr complex with a reaction intermediate
172 608 6a2pA Crystal structure of quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dhfr-ts complexed with bt3, nadph, and dump
168 604 6a2mA Crystal structure of wild type plasmodium falciparum dhfr-ts complexed with bt2, nadph, and dump
169 608 6a2nA Crystal structure of quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dhfr-ts complexed with bt2, nadph, and dump
58 186 6a7cA Human dihydrofolate reductase complexed with nadph and bt1
168 608 6a2oA Crystal structure of wild type plasmodium falciparum dhfr-ts complexed with bt3, nadph, and dump
166 605 6a2lA Crystal structure of quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dhfr-ts complexed with bt1, nadph, and dump
171 608 6a2kA Crystal structure of wild type plasmodium falciparum dhfr-ts complexed with bt1, nadph, and dump
42 157 5isqX Staphylococcus aureus h30n, f98y dihydrofolate reductase mutant complexed with beta-nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106)
42 157 5istX Staphylococcus aureus dihydrofolate reductase complexed with beta-nadph, cyclic alpha-nadph anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106)
169 608 3um8A Wild-type plasmodium falciparum dhfr-ts complexed with cycloguanil and nadph
43 165 3s9uA Bacillus anthracis dihydrofolate reductase bound to propargyl-linked tmp analog, ucp120j
45 165 3sa2A Bacuills anthracis dihydrofolate reductase bound propargyl-linked tmp analog, ucp1014
46 164 3sa1A Bacuills anthracis dihydrofolate reductase bound propargyl-linked tmp analog, ucp1021
45 165 3saiA Bacuills anthracis dihydrofolate reductase bound to propargyl-linked tmp analog, ucp1015
45 162 6mthA E. coli dhfr complex modeled with three ligand states
41 157 5jg0X Staphylococcus aureus dihydrofolate reductase complexed with beta-nadph and ucp1191
43 159 5ja3A Mycobacterium tuberculosis dihydrofolate reductase complexed with beta- nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-b iphenyl]-4-carboxylic acid (ucp1106)
54 186 5hvbA 5-methyl-6-(1-naphthylthio)thieno[2,3-d]pyrimidine 2,4-diamine
57 186 5hsrA Fluorine substituted 5-methyl-6-(3',4'-difluoromethoxyphenythio)thieno[2,3-d]pyrimidine-2,4-diamine
60 186 5hveA 5-methyl-6-(3'-trifluromethoxyphenylthio)[2,3-d]pyrimidine 2,4-diamine
50 186 5hpbA Human dihydrofolate reductase complex with nadph and 5-methyl-6-(phenylthio-4'trifluoromethyl)thieno[2,3-d]pyrimidine-2,4-diamine