Found 391 chains in Genus chains table. Displaying 1 - 50. Applied filters: Proteins

Search results query: DHFR_1

Total Genus Sequence Length pdb Title
42 157 5ispX Staphylococcus aureus f98y dihydrofolate reductase mutant complexed with beta-nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106)
43 162 6cw7A E. coli dhfr product complex with (6s)-5,6,7,8-tetrahydrofolate
42 161 6cyvA E. coli dhfr ternary complex with nadp and dihydrofolate
37 159 6cqaA E. coli dhfr complex with inhibitor ampqd
45 165 6cxkA E. coli dhfr substrate complex with dihydrofolate
57 186 6a7eA Human dihydrofolate reductase complexed with nadph and bt2
45 162 6mt8A E. coli dhfr complex modeled with two ligand states
45 162 6mr9A E. coli dhfr complex with a reaction intermediate
172 608 6a2pA Crystal structure of quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dhfr-ts complexed with bt3, nadph, and dump
168 604 6a2mA Crystal structure of wild type plasmodium falciparum dhfr-ts complexed with bt2, nadph, and dump
169 608 6a2nA Crystal structure of quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dhfr-ts complexed with bt2, nadph, and dump
58 186 6a7cA Human dihydrofolate reductase complexed with nadph and bt1
168 608 6a2oA Crystal structure of wild type plasmodium falciparum dhfr-ts complexed with bt3, nadph, and dump
166 605 6a2lA Crystal structure of quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dhfr-ts complexed with bt1, nadph, and dump
171 608 6a2kA Crystal structure of wild type plasmodium falciparum dhfr-ts complexed with bt1, nadph, and dump
42 157 5isqX Staphylococcus aureus h30n, f98y dihydrofolate reductase mutant complexed with beta-nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106)
42 157 5istX Staphylococcus aureus dihydrofolate reductase complexed with beta-nadph, cyclic alpha-nadph anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (ucp1106)
169 608 3um8A Wild-type plasmodium falciparum dhfr-ts complexed with cycloguanil and nadph
43 165 3s9uA Bacillus anthracis dihydrofolate reductase bound to propargyl-linked tmp analog, ucp120j
45 165 3sa2A Bacuills anthracis dihydrofolate reductase bound propargyl-linked tmp analog, ucp1014
46 164 3sa1A Bacuills anthracis dihydrofolate reductase bound propargyl-linked tmp analog, ucp1021
45 165 3saiA Bacuills anthracis dihydrofolate reductase bound to propargyl-linked tmp analog, ucp1015
45 162 6mthA E. coli dhfr complex modeled with three ligand states
41 157 5jg0X Staphylococcus aureus dihydrofolate reductase complexed with beta-nadph and ucp1191
43 159 5ja3A Mycobacterium tuberculosis dihydrofolate reductase complexed with beta- nadph and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-b iphenyl]-4-carboxylic acid (ucp1106)
54 186 5hvbA 5-methyl-6-(1-naphthylthio)thieno[2,3-d]pyrimidine 2,4-diamine
57 186 5hsrA Fluorine substituted 5-methyl-6-(3',4'-difluoromethoxyphenythio)thieno[2,3-d]pyrimidine-2,4-diamine
60 186 5hveA 5-methyl-6-(3'-trifluromethoxyphenylthio)[2,3-d]pyrimidine 2,4-diamine
50 186 5hpbA Human dihydrofolate reductase complex with nadph and 5-methyl-6-(phenylthio-4'trifluoromethyl)thieno[2,3-d]pyrimidine-2,4-diamine
53 186 5ht5A 6-substituted pyrrolo[2,3-d]pyrimidine 6-thieno-(4-methoxyphenyl)
55 186 5hqzA Fluorine substituted 5-methyl-6-(4'-trifluoromethoxyphenythio)thieno[2,3-d]pyrimidine-2,4-diamine
53 186 5hqyA Human dihydrofolate reductase complex with nadph and 5-methyl-6-(2',3',4'-trifluorophenylthio)thieno[2,3-d]pyrimidine-2,4-diamine
56 186 5hsuA Fluorine substituted 5-methyl-6-(2',4'-difluoromethoxyphenythio)thieno[2,3-d]pyrimidine-2,4-diamine
53 186 5huiA 6-substituted pyrido[3,2-d]pyrimidine--6-4'-trifluoromethoxyphenyl)
54 186 8dfrA Refined crystal structures of chicken liver dihydrofolate reductase. 3 angstroms apo-enzyme and 1.7 angstroms nadph holo-enzyme complex
40 159 7dfrA Crystal structures of escherichia coli dihydrofolate reductase. the nadp+ holoenzyme and the folate(dot)nadp+ ternary complex. substrate binding and a model for the transition state
42 159 6e4eA Crystal structure of dihydrofolate reductase from staphylococcus aureus mw2 bound to nadp and p218
44 159 6ddwA Mycobacterium tuberculosis dihydrofolate reductase complexed with beta-nadph and n-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-2-hydroxybenzene-1-carbonyl)-l-glutamic acid
42 159 6ddpA Mycobacterium tuberculosis dihydrofolate reductase complexed with beta-nadph and 3'-[(2r)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-5'-methoxy[1,1'-biphenyl]-4-carboxylic acid
41 159 6ddsA Mycobacterium tuberculosis dihydrofolate reductase complexed with beta-nadph and 4-[3-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]prop-2-ynyl]-5-methoxy-phenyl]benzoic acid
57 186 6davA Crystal structure of human dhfr complexed with nadp and n10formyltetrahydrofolate
40 159 6dfrA Crystal structures of escherichia coli dihydrofolate reductase. the nadp+ holoenzyme and the folate(dot)nadp+ ternary complex. substrate binding and a model for the transition state
53 186 6de4A Homo sapiens dihydrofolate reductase complexed with beta-nadph and 3'-[(2r)-4-(2,4-diamino-6-ethylphenyl)but-3-yn-2-yl]-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid
38 155 6cxmA Crystal structure of a dihydrofolate reductase from mycobacterium smegmatis in complex with nadp and p218
41 160 5z6lA High-pressure crystal structure analysis of m20 loop closed dhfr at 650 mpa
44 160 5z6jA High-pressure crystal structure analysis of m20 loop closed dhfr at 220 mpa
36 160 5z6mA High-pressure crystal structure analysis of m20 loop closed dhfr at 800 mpa
46 160 5z6fA High-pressure crystal structure analysis of dhfr(0.1 mpa)
44 160 5z6kA High-pressure crystal structure analysis of m20 loop closed dhfr at 400 mpa
45 159 5cc9A L28f e.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate