|
86
|
330
|
5hcoA |
Endothiapepsin in complex with hydrazide |
|
106
|
390
|
5hdxA |
Bace-1 in complex with (7ar)-7a-(5-cyanothiophen-2-yl)-6-(4-ethoxy-5-fluoro-6-methylpyrimidin-2-yl)-3-methyl-4-oxooctahydro-2h-pyrrolo[3,4-d]pyrimidin-2-iminium |
|
108
|
390
|
5he4A |
Bace-1 in complex with (4ar,7as)-7a-(2,6-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-3-methyl-4-oxooctahydro-2h-pyrrolo[3,4-d]pyrimidin-2-iminium |
|
103
|
390
|
5hduA |
Bace-1 incomplex with (7ar)-7a-(4-(3-cyanophenyl)thiophen-2-yl)-6-(5-fluoro-4-methoxypyrimidin-2-yl)-3-methyl-4-oxooctahydro-2h-pyrrolo[3,4-d]pyrimidin-2-iminium |
|
106
|
390
|
5he5A |
Bace-1 in complex with (7ar)-7a-(5-cyanothiophen-2-yl)-6-(5-fluoro-4-methyl-6-(methylamino)pyrimidin-2-yl)-3-methyl-4-oxooctahydro-2h-pyrrolo[3,4-d]pyrimidin-2-iminium |
|
81
|
330
|
4zeaA |
Endothiapepsin in complex with fragment b91 |
|
103
|
390
|
5hdvA |
Bace-1 incomplex with (7ar)-7a-(5-cyanothiophen-2-yl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-3-methyl-4-oxooctahydro-2h-pyrrolo[3,4-d]pyrimidin-2-iminium |
|
87
|
330
|
5hctA |
Endothiapepsin in complex with biacylhydrazone |
|
103
|
390
|
5hdzA |
Bace-1 in complex with (7ar)-7a-(5-cyanothiophen-2-yl)-6-(5-fluoro-4-methyl-6-(methylthio)pyrimidin-2-yl)-3-methyl-4-oxooctahydro-2h-pyrrolo[3,4-d]pyrimidin-2-iminium |
|
105
|
390
|
5hd0A |
Bace-1 in complex with (7ar)-7a-(4-(3-cyanophenyl)thiophen-2-yl)-6-(5-fluoropyrimidin-2-yl)-3-methyl-4-oxooctahydro-2h-pyrrolo[3,4-d]pyrimidin-2-iminium |
|
98
|
390
|
5f01A |
Crystal structure of bace-1 in complex with (1sr,2sr)-2-((r)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4h-1,3-oxazin-4-yl)-n-(3-chloroquinolin-8-yl)cyclopropanecarboxamide |
|
27
|
112
|
5fivA |
Structural studies of hiv and fiv proteases complexed with an efficient inhibitor of fiv pr |
|
99
|
390
|
5f00A |
Crystal structure of bace-1 in complex with 5-[3-[(3-chloro-8-quinolyl)amino]phenyl]-5-methyl-2,6-dihydro-1,4-oxazin-3-amine |
|
88
|
387
|
5enmA |
Compound 10 |
|
18
|
99
|
5e5kA |
Joint x-ray/neutron structure of hiv-1 protease triple mutant (v32i,i47v,v82i) with darunavir at ph 4.3 |
|
106
|
390
|
4zspA |
Bace crystal structure with bicyclic aminothiazine inhibitor |
|
90
|
387
|
5enkA |
Compound 18 |
|
99
|
389
|
4zsqA |
Bace crystal structure with tricyclic aminothiazine inhibitor |
|
73
|
330
|
5er1E |
A rational approach to the design of antihypertensives. x-ray studies of complexes between aspartic proteinases and aminoalcohol renin inhibitors |
|
19
|
99
|
5e5jA |
Joint x-ray/neutron structure of hiv-1 protease triple mutant (v32i,i47v,v82i) with darunavir at ph 6.0 |
|
101
|
390
|
5ezzA |
Crystal structure of bace-1 in complex with (4s)-4-[3-(5-chloro-3-pyridyl)phenyl]-4-[4-(difluoromethoxy)-3-methyl-phenyl]-5h-oxazol-2-amine |
|
80
|
330
|
5er2E |
High-resolution x-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor. the analysis of the inhibitor binding and description of the rigid body shift in the enzyme |
|
89
|
325
|
5aprE |
Structures of complexes of rhizopuspepsin with pepstatin and other statine-containing inhibitors |
|
107
|
390
|
4zsrA |
Bace crystal structure with tricyclic aminothiazine inhibitor |
|
101
|
389
|
4zsmA |
Bace crystal structure with bicyclic aminothiazine fragment |
|
84
|
330
|
5dr3A |
Endothiapepsin in complex with fragment 333 |
|
82
|
330
|
5dq1A |
Endothiapepsin in complex with fragment 34 |
|
86
|
330
|
5dr8A |
Endothiapepsin in complex with fragment 330 |
|
86
|
330
|
5dr1A |
Endothiapepsin in complex with fragment 278 |
|
85
|
330
|
5dr0A |
Endothiapepsin in complex with fragment 203 |
|
84
|
330
|
5dr7A |
Endothiapepsin in complex with fragment 311 |
|
83
|
330
|
5dpzA |
Endothiapepsin in complex with fragment 31 |
|
83
|
330
|
5dq2A |
Endothiapepsin in complex with fragment 48 |
|
85
|
330
|
5dq5A |
Endothiapepsin in complex with fragment 209 |
|
85
|
330
|
5dq4A |
Endothiapepsin in complex with fragment 66 |
|
84
|
330
|
5dr4A |
Endothiapepsin in complex with fragment 231 |
|
100
|
388
|
5dqcA |
Co-crystal of bace1 with compound 0211 |
|
100
|
389
|
4zpfA |
Bace1 in complex with 8-(3-((1-aminopropan-2-yl)oxy)benzyl)-4-(cyclohexylamino)-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one |
|
98
|
389
|
4zpgA |
Bace1 in complex with 8-benzyl-4-(cyclohexylamino)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]dec-3-en-2-one |
|
18
|
99
|
5dguA |
Crystal structure of hiv-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as p2-ligand grl-004-11a |
|
95
|
389
|
4zpeA |
Bace1 in complex with 4-(cyclohexylamino)-1-(3-fluorophenyl)-8-(3-isopropoxybenzyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one |
|
18
|
99
|
5dgwA |
Crystal structure of hiv-1 protease inhibitor grl-105-11a containing substituted fused-tetrahydropyranyl tetrahydrofuran as p2-ligand |
|
83
|
330
|
4yctA |
Endothiapepsin in complex with fragment 216 |
|
17
|
99
|
4yobA |
Crystal structure of apo hiv-1 protease mdr769 l33f |
|
83
|
330
|
4yd7A |
Endothiapepsin in complex with fragment 255 |
|
16
|
99
|
4yoaA |
Crsystal structure hiv-1 protease mdr769 l33f complexed with darunavir |
|
20
|
99
|
4yhqA |
Crystal structure of multidrug resistant clinical isolate pr20 with grl-5010a |
|
19
|
99
|
5copA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-097 |
|
93
|
333
|
4y9wA |
Aspartic proteinase sapp2 secreted from candida parapsilosis at 0.82 a resolution. |
|
17
|
99
|
5ahaA |
Disubstituted bis-thf moieties as new p2 ligands in non-peptidal hiv- 1 protease inhibitors (ii) |
