81
|
263
|
3octA |
Crystal structure of bruton's tyrosine kinase mutant v555r in complex with dasatinib |
82
|
277
|
3oezA |
Crystal structure of the l317i mutant of the chicken c-src tyrosine kinase domain complexed with imatinib |
76
|
277
|
3of0A |
Crystal structure of the l317i mutant of the chicken c-src tyrosine kinase domain |
89
|
264
|
3ocsA |
Crystal structure of bruton's tyrosine kinase in complex with inhibitor cgi1746 |
89
|
290
|
3nyxA |
Non-phosphorylated tyk2 jh1 domain with quinoline-thiadiazole-thiophene inhibitor |
92
|
291
|
3nz0A |
Non-phosphorylated tyk2 kinase with cmp6 |
31
|
163
|
3nhnA |
Crystal structure of the src-family kinase hck sh3-sh2-linker regulatory region |
82
|
274
|
3mssA |
Abl kinase in complex with imatinib and fragment (frag2) in the myristate site |
83
|
275
|
3ms9A |
Abl kinase in complex with imatinib and a fragment (frag1) in the myristate pocket |
82
|
261
|
3mpmA |
Lck complexed with a pyrazolopyrimidine |
90
|
291
|
3lxnA |
Structural and thermodynamic characterization of the tyk2 and jak3 kinase domains in complex with cp-690550 and cmp-6 |
89
|
284
|
3lxkA |
Structural and thermodynamic characterization of the tyk2 and jak3 kinase domains in complex with cp-690550 and cmp-6 |
73
|
261
|
3mj1A |
X-ray crystal structure of itk complexed with inhibitor ro5191614 |
81
|
259
|
3mj2A |
X-ray crystal structure of itk complexed with inhibitor bms-509744 |
97
|
291
|
3lxpA |
Structural and thermodynamic characterization of the tyk2 and jak3 kinase domains in complex with cp-690550 and cmp-6 |
78
|
265
|
3miyA |
X-ray crystal structure of itk complexed with sunitinib |
88
|
285
|
3lxlA |
Structural and thermodynamic characterization of the tyk2 and jak3 kinase domains in complex with cp-690550 and cmp-6 |
100
|
290
|
3lpbA |
Crystal structure of jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitor |
68
|
277
|
3lokA |
Drug resistant csrc kinase domain in complex with covalent inhibitor pd168393 |
82
|
264
|
3kxzA |
The complex crystal structure of lck with a probe molecule w259 |
92
|
271
|
3lckA |
The kinase domain of human lymphocyte kinase (lck), activated form (auto-phosphorylated on tyr394) |
83
|
271
|
3kmmA |
Structure of human lck kinase with a small molecule inhibitor |
92
|
289
|
3kckA |
A novel chemotype of kinase inhibitors |
90
|
284
|
3kfaA |
Structural analysis of dfg-in and dfg-out dual src-abl inhibitors sharing a common vinyl purine template |
99
|
293
|
3krrA |
Crystal structure of jak2 complexed with a potent quinoxaline atp site inhibitor |
88
|
286
|
3kf4A |
Structural analysis of dfg-in and dfg-out dual src-abl inhibitors sharing a common vinyl purine template |
81
|
267
|
3k54A |
Structures of human bruton's tyrosine kinase in active and inactive conformations suggests a mechanism of activation for tec family kinases. |
25
|
100
|
3k2mA |
Crystal structure of monobody ha4/abl1 sh2 domain complex |
88
|
287
|
3k5vA |
Structure of abl kinase in complex with imatinib and gnf-2 |
89
|
289
|
3jy9A |
Janus kinase 2 inhibitors |
97
|
289
|
3iokA |
2-aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of jak2 |
96
|
289
|
3io7A |
2-aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of jak2 |
88
|
286
|
3ik3A |
Ap24534, a pan-bcr-abl inhibitor for chronic myeloid leukemia, potently inhibits the t315i mutant and overcomes mutation-based resistance |
81
|
277
|
3h3cA |
Crystal structure of pyk2 in complex with sulfoximine-substituted trifluoromethylpyrimidine analog |
15
|
107
|
3hckA |
Nmr ensemble of the uncomplexed human hck sh2 domain, 20 structures |
85
|
268
|
3hmiA |
The crystal structure of human abl2 in complex with 5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide |
91
|
267
|
3genA |
The 1.6 a crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound |
10
|
63
|
3h0hA |
Human fyn sh3 domain r96i mutant, crystal form i |
57
|
140
|
3gm1A |
Crystal structure of the focal adhesion targeting (fat) domain of pyk2 in complex with paxillin ld4 motif-derived peptides |
55
|
133
|
3gm3A |
Crystal structure of the focal adhesion targeting (fat) domain of pyk2 |
11
|
59
|
3h0fA |
Crystal structure of the human fyn sh3 r96w mutant |
11
|
59
|
3h0iA |
Human fyn sh3 domain r96i mutant, crystal form ii |
51
|
127
|
3gm2A |
Crystal structure of the focal adhesion targeting (fat) domain of pyk2 |
83
|
278
|
3gvuA |
The crystal structure of human abl2 in complex with gleevec |
77
|
286
|
3geqA |
Structural basis for the chemical rescue of src kinase activity |
92
|
272
|
3fqhA |
Crystal structure of spleen tyrosine kinase complexed with a 2-substituted 7-azaindole |
80
|
277
|
3g5dA |
Kinase domain of csrc in complex with dasatinib |
81
|
278
|
3g6gA |
Equally potent inhibition of c-src and abl by compounds that recognize inactive kinase conformations |
92
|
277
|
3fqsA |
Crystal structure of spleen tyrosine kinase complexed with r406 |
92
|
290
|
3fupA |
Crystal structures of jak1 and jak2 inhibitor complexes |