|
97
|
291
|
4gfmA |
Jak2 kinase (jh1 domain) with 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide |
|
88
|
288
|
4gj3A |
Tyk2 (jh1) in complex with 2,6-dichloro-4-cyano-n-[2-({[(1r,2r)-2-fluorocyclopropyl]carbonyl}amino)pyridin-4-yl]benzamide |
|
91
|
277
|
4gfgA |
Crystal structure of spleen tyrosine kinase complexed with r9021 |
|
87
|
289
|
4giiA |
Tyk2 (jh1) in complex with 2,6-dichloro-4-cyano-n-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamide |
|
91
|
288
|
4gj2A |
Tyk2 (jh1) in complex with 2,6-dichloro-n-[2-({[(1r,2r)-2-fluorocyclopropyl]carbonyl}amino)pyridin-4-yl]benzamide |
|
92
|
300
|
4gmyA |
Jak2 kinase (jh1 domain) in complex with 2,6-dichloro-n-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamide |
|
95
|
288
|
4gihA |
Tyk2 (jh1) in complex with 2,6-dichloro-n-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamide |
|
78
|
288
|
4gl9A |
Crystal structure of inhibitory protein socs3 in complex with jak2 kinase domain and fragment of gp130 intracellular domain |
|
84
|
289
|
4gfoA |
Tyk2 kinase (jh1 domain) with 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide |
|
89
|
277
|
4fynA |
Crystal structure of spleen tyrosine kinase complexed with 3-(8-{4-[ethyl-(2-hydroxy-ethyl)-amino]-phenylamino}-imidazo[1,2-a]pyrazin-5-yl)-phenol |
|
87
|
277
|
4fz7A |
Crystal structure of spleen tyrosine kinase complexed with 6-((1r,2s)-2-amino-cyclohexylamino)-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide |
|
85
|
274
|
4fvqA |
Crystal structure of the jak2 pseudokinase domain (mg-atp-bound form) |
|
86
|
274
|
4fvpA |
Crystal structure of the jak2 pseudokinase domain (apo form) |
|
83
|
274
|
4fvrA |
Crystal structure of the jak2 pseudokinase domain mutant v617f (mg-atp-bound form) |
|
88
|
277
|
4fyoA |
Crystal structure of spleen tyrosine kinase complexed with n-{(s)-1-[7-(3,4-dimethoxy-phenylamino)-thiazolo[5,4-d]pyrimidin-5-yl]-pyrrolidin-3-yl}-terephthalamic acid |
|
88
|
277
|
4fz6A |
Crystal structure of spleen tyrosine kinase complexed with [6-((s)-2-methyl-pyrrolidin-1-yl)-pyridin-2-yl]-(6-phenyl-imidazo[1,2-b]pyridazin-8-yl)-amine |
|
72
|
279
|
4ficA |
Kinase domain of csrc in complex with a hinge region-binding fragment |
|
85
|
292
|
4fk6A |
Jak1 kinase (jh1 domain) in complex with compound 72 |
|
179
|
627
|
4fl2A |
Structural and biophysical characterization of the syk activation switch |
|
86
|
273
|
4fl1A |
Structural and biophysical characterization of the syk activation switch |
|
180
|
627
|
4fl3A |
Structural and biophysical characterization of the syk activation switch |
|
84
|
270
|
3qrkA |
The crystal structure of human abl1 kinase domain in complex with dp-987 |
|
88
|
263
|
3qrjA |
The crystal structure of human abl1 kinase domain t315i mutant in complex with dcc-2036 |
|
73
|
276
|
3qlfA |
Crystal structure of the l317i mutant of the c-src tyrosine kinase domain complexed with pyrazolopyrimidine 5 |
|
74
|
261
|
3qgwA |
Crystal structure of itk kinase bound to an inhibitor |
|
74
|
276
|
3qlgA |
Crystal structure of the l317i mutant of the c-src tyrosine kinase domain complexed with dasatinib |
|
85
|
275
|
3qriA |
The crystal structure of human abl1 kinase domain in complex with dcc-2036 |
|
78
|
264
|
3qgyA |
Crystal structure of itk inhibitor complex |
|
85
|
269
|
3pyyA |
Discovery and characterization of a cell-permeable, small-molecule c-abl kinase activator that binds to the myristoyl binding site |
|
90
|
273
|
3pxkA |
Focal adhesion kinase catalytic domain in complex with pyrrolo[2,3-d]thiazole |
|
96
|
293
|
3q32A |
Structure of janus kinase 2 with a pyrrolotriazine inhibitor |
|
82
|
269
|
3pj2A |
Crystal structure of btk kinase domain complexed with 2-[4-(2-diethylamino-ethoxy)-phenylamino]-6-(4-fluoro-phenoxy)-8-methyl-8h-pyrido[2,3-d]pyrimidin-7-one |
|
88
|
290
|
3pjcA |
Crystal structure of jak3 complexed with a potent atp site inhibitor showing high selectivity within the janus kinase family |
|
81
|
269
|
3pj1A |
Crystal structure of btk kinase domain complexed with 3-(2,6-dichloro-phenyl)-7-[4-(2-diethylamino-ethoxy)-phenylamino]-1-methyl-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one |
|
94
|
268
|
3pixA |
Crystal structure of btk kinase domain complexed with 2-isopropyl-7-(4-methyl-piperazin-1-yl)-4-(5-methyl-2h-pyrazol-3-ylamino)-2h-phthalazin-1-one |
|
81
|
269
|
3pizA |
Crystal structure of btk kinase domain complexed with (5-amino-1-o-tolyl-1h-pyrazol-4-yl)-[3-(1-methanesulfonyl-piperidin-4-yl)-phenyl]-methanone |
|
88
|
268
|
3piyA |
Crystal structure of btk kinase domain complexed with r406 |
|
81
|
269
|
3pj3A |
Crystal structure of btk kinase domain complexed with 2-methyl-5-[(e)-(3-phenyl-acryloyl)amino]-n-(2-phenyl-3h-imidazo[4,5-b]pyridin-6-yl)-benzamide |
|
89
|
284
|
3oxzA |
Crystal structure of abl kinase domain bound with a dfg-out inhibitor ap24534 |
|
88
|
284
|
3oy3A |
Crystal structure of abl t315i mutant kinase domain bound with a dfg-out inhibitor ap24589 |
|
80
|
265
|
3p08A |
Crystal structure of the human btk kinase domain |
|
81
|
263
|
3octA |
Crystal structure of bruton's tyrosine kinase mutant v555r in complex with dasatinib |
|
82
|
277
|
3oezA |
Crystal structure of the l317i mutant of the chicken c-src tyrosine kinase domain complexed with imatinib |
|
76
|
277
|
3of0A |
Crystal structure of the l317i mutant of the chicken c-src tyrosine kinase domain |
|
89
|
290
|
3nyxA |
Non-phosphorylated tyk2 jh1 domain with quinoline-thiadiazole-thiophene inhibitor |
|
92
|
291
|
3nz0A |
Non-phosphorylated tyk2 kinase with cmp6 |
|
89
|
264
|
3ocsA |
Crystal structure of bruton's tyrosine kinase in complex with inhibitor cgi1746 |
|
31
|
163
|
3nhnA |
Crystal structure of the src-family kinase hck sh3-sh2-linker regulatory region |
|
83
|
275
|
3ms9A |
Abl kinase in complex with imatinib and a fragment (frag1) in the myristate pocket |
|
82
|
261
|
3mpmA |
Lck complexed with a pyrazolopyrimidine |
