|
96
|
290
|
4irrA |
Crystal structure of c.elegans thymidylate synthase in complex with dump |
|
84
|
281
|
4h1iA |
Structure of human thymidylate synthase at low salt conditions |
|
73
|
285
|
4gyhA |
Structure of human thymidylate synthase at high salt conditions |
|
79
|
260
|
4h0rA |
Crystal structure of thymidylate synthase from corynebacterium glutamicum |
|
81
|
264
|
4h0uA |
Crystal structure of thymidylate synthase from corynebacterium glutamicum in complex with dump |
|
73
|
284
|
4g6wX |
Human thymidylate synthase m190k with bound 4-bromobenzene-1,2,3-triol |
|
79
|
263
|
4gevA |
E. coli thymidylate synthase y209w variant in complex with substrate and a cofactor analog |
|
75
|
284
|
4gd7A |
Wild-type human thymidylate synthase with bound purpurogallin |
|
76
|
284
|
4g2oX |
Human thymidylate synthase m190k with bound purpurogallin |
|
85
|
263
|
4fqsA |
Crystal structure of mycobacterium tuberculosis thya in complex with ump and pemetrexed |
|
84
|
283
|
4fgtA |
Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme. |
|
76
|
260
|
4fogA |
Crystal structure of mtb thya in complex with 5-fluoro-dump and 5-methyltetrahydrofolic acid |
|
83
|
261
|
4foaA |
Crystal structure of the mtb thya in complex with 5-fluoro-dump |
|
79
|
261
|
4foxA |
Crystal structure of mtb thya in complex with dump and raltitrexed |
|
173
|
608
|
3qg2A |
Plasmodium falciparum dhfr-ts qradruple mutant (n51i+c59r+s108n+i164l, v1/s) pyrimethamine complex |
|
177
|
608
|
3qgtA |
Crystal structure of wild-type pfdhfr-ts complexed with nadph, dump and pyrimethamine |
|
83
|
260
|
3qj7A |
Crystal structure of the mycobacterium tuberculosis thymidylate synthase (thya) bound to dump |
|
90
|
281
|
3ob7A |
Human thymidylate synthase r163k with cys 195 covalently modified by glutathione |
|
162
|
509
|
3nrrA |
Co-crystal structure of dihydrofolate reductase-thymidylate synthase from babesia bovis with dump, raltitrexed and nadp |
|
71
|
285
|
3n5eB |
Crystal structure of human thymidylate synthase bound to a peptide inhibitor |
|
75
|
285
|
3n5gA |
Crystal structure of histidine-tagged human thymidylate synthase |
|
70
|
285
|
3n5eA |
Crystal structure of human thymidylate synthase bound to a peptide inhibitor |
|
152
|
514
|
3kjsA |
Crystal structure of t. cruzi dhfr-ts with 3 high affinity dhfr inhibitors: dq1 inhibitor complex |
|
76
|
279
|
3kgbA |
Crystal structure of thymidylate synthase 1/2 from encephalitozoon cuniculi at 2.2 a resolution |
|
159
|
507
|
3kjrA |
Crystal structure of dihydrofolate reductase/thymidylate synthase from babesia bovis determined using slipchip based microfluidics |
|
177
|
606
|
3jsuA |
Quadruple mutant(n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase(pfdhfr-ts) complexed with qn254, nadph, and dump |
|
163
|
508
|
3k2hA |
Co-crystal structure of dihydrofolate reductase/thymidylate synthase from babesia bovis with dump, pemetrexed and nadp |
|
160
|
514
|
3invA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with nadph, dump and c-448 antifolate |
|
156
|
518
|
3iroA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with nadph and q-8 antifolate |
|
161
|
520
|
3irmA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with cycloguanil |
|
152
|
516
|
3irnA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with nadph and cycloguanil |
|
80
|
251
|
3ix6A |
Crystal structure of thymidylate synthase thya from brucella melitensis |
|
97
|
311
|
3ik1A |
Lactobacillus casei thymidylate synthase in ternary complex with dump and the phtalimidic derivative 20c |
|
90
|
280
|
3ihiA |
Crystal structure of mouse thymidylate synthase |
|
96
|
312
|
3ijzA |
Lactobacillus casei thymidylate synthase ternary complex with dump and pthalimidic derivative 15c |
|
96
|
312
|
3ik0A |
Lactobacillus casei thymidylate synthase in ternary complex with dump and the phtalimidic derivative 7c1 |
|
155
|
506
|
3i3rA |
X-ray structure dihydrofolate reductase/thymidylate synthase from babesia bovis at 2.35a resolution |
|
92
|
281
|
3hb8A |
Structures of thymidylate synthase r163k with substrates and inhibitors show subunit asymmetry |
|
89
|
281
|
3h9kA |
Structures of thymidylate synthase r163k with substrates and inhibitors show subunit asymmetry |
|
157
|
515
|
3hbbA |
Structures of dihydrofolate reductase-thymidylate synthase of trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate |
|
167
|
519
|
3hj3A |
Crystal structure of the chts-dhfr f207a non-active site mutant |
|
83
|
283
|
3gg5A |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
81
|
304
|
3gh2X |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
76
|
307
|
3gh0A |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
71
|
285
|
3ebuA |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
82
|
283
|
3ejlA |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
60
|
285
|
3ef9A |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
80
|
285
|
3ehiX |
Crystal structure of human thymidyalte synthase m190k with loop 181-197 stabilized in the inactive conformation |
|
79
|
285
|
3edwX |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
64
|
284
|
3egyX |
Crystal structure of human thymidyalte synthase a191k with loop 181-197 stabilized in the inactive conformation |
