|
69
|
285
|
3eawX |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
79
|
289
|
3ed7A |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
168
|
519
|
3dl5A |
Crystal structure of the a287f active site mutant of ts-dhfr from cryptosporidium hominis |
|
156
|
519
|
3dl6A |
Crystal structure of the a287f/s290g active site mutant of ts-dhfr from cryptosporidium hominis |
|
103
|
325
|
3dgaC |
Wild-type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with rjf01302, nadph, and dump |
|
103
|
326
|
3dg8C |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with rjf670, nadph, and dump |
|
153
|
515
|
3clbA |
Structure of bifunctional tcdhfr-ts in complex with tmq |
|
140
|
513
|
3cl9A |
Structure of bifunctional tcdhfr-ts in complex with mtx |
|
99
|
315
|
3byxA |
Lactobacillus casei thymidylate synthase ternary complex with dump and the phtalimidic derivative c00 in multiple binding modes |
|
89
|
312
|
3bz0A |
Lactobacillus casei thymidylate synthase ternary complex with dump and the phtalimidic derivative c00 |
|
90
|
316
|
3c06A |
Lactobacillus casei thymidylate synthase ternary complex with dump and the phtalimidic derivative 14c in multiple binding modes-mode 1 |
|
81
|
313
|
3c0aA |
Lactobacillus casei thymidylate synthase ternary complex with dump and the phtalimidic derivative 14c in multiple binding modes-mode 2 |
|
86
|
263
|
3bhrA |
E. coli ts complexed with 5-no2dump and tetrahydrofolate at 1.9 a resolution (space group 152) |
|
89
|
314
|
3bnzA |
Crystal structure of thymidylate synthase ternary complex with dump and 8a inhibitor |
|
86
|
263
|
3bhlA |
E.coli thymidylate synthase complexes with 5-no2dump and tetrahydrofolate at 1.4 a resolution |
|
86
|
263
|
3bgxA |
E. coli thymidylate synthase c146s mutant complexed with dtmp and mtf |
|
84
|
263
|
3bfiA |
E. coli thymidylate synthase y209m mutant complexed with 5-nitro-dump |
|
85
|
263
|
3b9hA |
E. coli thymidylate synthase complexed with 5-nitro-2'-deoxy uridine |
|
81
|
264
|
3b5bA |
Crystal structure of the thymidylate synthase k48q |
|
83
|
263
|
2vf0A |
Crystal structure of the thymidylate synthase k48q complexed with 5no2dump and bw1843u89 |
|
88
|
264
|
2vetA |
Crystal structure of the thymidylate synthase k48q complexed with dump |
|
84
|
264
|
2tscA |
Structure, multiple site binding, and segmental accomodation in thymidylate synthase on binding d/ump and an anti-folate |
|
93
|
315
|
2tddA |
Structures of thymidylate synthase with a c-terminal deletion: role of the c-terminus in alignment of d/ump and ch2h4folate |
|
92
|
281
|
2tsrA |
Thymidylate synthase from rat in ternary complex with dump and tomudex |
|
98
|
283
|
2rd8A |
Human thymidylate synthase stabilized in active conformation by r163k mutation: asymmetry and reactivity of cys195 |
|
104
|
316
|
2tdmA |
Structure of thymidylate synthase |
|
86
|
284
|
2rd8B |
Human thymidylate synthase stabilized in active conformation by r163k mutation: asymmetry and reactivity of cys195 |
|
87
|
282
|
2rdaA |
Human thymidylate synthase stabilized in active conformation by r163k mutation: asymmetry and reactivity of cys195 |
|
72
|
285
|
2onbA |
Human thymidylate synthase at low salt conditions with pdpa bound |
|
166
|
519
|
2oipA |
Crystal structure of the s290g active site mutant of ts-dhfr from cryptosporidium hominis |
|
77
|
264
|
2kceA |
Binding of the anticancer drug zd1694 to e. coli thymidylate synthase: assessing specificity and affinity |
|
160
|
514
|
2h2qA |
Crystal structure of trypanosoma cruzi dihydrofolate reductase-thymidylate synthase |
|
95
|
316
|
2g8aA |
Lactobacillus casei y261m in complex with substrate, dump |
|
84
|
261
|
2g8xA |
Escherichia coli y209w apoprotein |
|
98
|
316
|
2g86A |
L. casei thymidylate synthase y261f in complex with substrate, dump |
|
102
|
316
|
2g89A |
L. casei thymidylate synthase y261a in complex with substrate, dump |
|
96
|
316
|
2g8dA |
Lactobacillus casei thymidylate synthase y261w-dump complex |
|
86
|
263
|
2ftoX |
Y94f mutant of thymidylate synthase bound to thymidine-5'-phosphate and 10-propargyl-5,8-dideazafolid acid |
|
82
|
263
|
2ftnA |
E. coli thymidylate synthase y94f mutant |
|
86
|
263
|
2ftqA |
E. coli thymidylate synthase at 1.8 a resolution |
|
78
|
264
|
2bbqA |
Structural basis for recognition of polyglutamyl folates by thymidylate synthase |
|
98
|
305
|
2aazA |
Cryptococcus neoformans thymidylate synthase complexed with substrate and an antifolate |
|
80
|
263
|
2a9wA |
E. coli ts complexed with dump and inhibitor ga9 |
|
83
|
263
|
1zprA |
E. coli thymidylate synthase mutant e58q in complex with cb3717 and 2'-deoxyuridine 5'-monophosphate (dump) |
|
70
|
308
|
1ypvA |
Structure of human thymidylate synthase at low salt conditions |
|
92
|
316
|
1vzbA |
L. casei thymidylate synthase mutant e60q binary complex with dump |
|
83
|
316
|
1vzdA |
L. casei thymidylate synthase mutant e60q ternary complex with fdump and cb3717 |
|
88
|
316
|
1vzaA |
Thymidylate synthase e60d mutant binary complex with 2'-deoxyuridine 5'-monophosphate (dump) |
|
91
|
316
|
1vzcA |
L. casei thymidylate synthase mutant e60q binary complex with fdump |
|
85
|
316
|
1vzeA |
L. casei thymidylate synthase mutant e60q ternary complex with dump and cb3717 |
