90
|
270
|
7mu7A |
Ask1 bound to compound 3 |
96
|
334
|
7n91A |
P70 s6k1 in complex with msc2317067a-1 |
128
|
394
|
7ei4A |
Crystal structure of masl in complex with a novel covalent inhibitor, collimonin c |
296
|
835
|
8fg8A |
Catalytic domain of gtfb in complex with inhibitor 2-[(2,4,5-trihydroxyphenyl)methylidene]-1-benzofuran-3-one |
165
|
462
|
8fjtA |
Human mitochondrial serine hydroxymethyltransferase (shmt2) in complex with plp, glycine and agf362 inhibitor |
148
|
462
|
8fjuA |
Human mitochondrial serine hydroxymethyltransferase (shmt2) in complex with plp, glycine and agf347 inhibitor |
88
|
322
|
8g63A |
Ralimetinib (ly2228820) in complex with wild type egfr |
118
|
385
|
8fbqA |
Crystal structure of plasmodium vivax glycylpeptide n-tetradecanoyltransferase (n-myristoyltransferase, nmt) bound to myristoyl-coa and inhibitor 12b |
79
|
209
|
7xbaA |
Glutathione s-transferase bound with a covalent inhibitor |
88
|
246
|
8s9mA |
Dna cytosine-n4 methyltransferase (residues 79-324) from the bdelloid rotifer adineta vaga |
85
|
258
|
8s9oA |
Dna cytosine-n4 methyltransferase (residues 61-324) from the bdelloid rotifer adineta vaga - p1 crystal form |
81
|
257
|
8s9nA |
Dna cytosine-n4 methyltransferase (residues 61-324) from the bdelloid rotifer adineta vaga - c2 crystal form |
62
|
222
|
8fx1A |
Crystal structure of the trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (hgxprt), isoform d, bound to (r)-serme-immh phosphonate |
63
|
222
|
8fwzA |
Crystal structure of the trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (hgxprt), isoform d, bound to hydroxypropyl-lin-immh phosphonate |
63
|
223
|
8fx3A |
Crystal structure of the trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (hgxprt), isoform d, bound to immucillin-gp, showing the structure of the complete active site in its open conformation |
62
|
222
|
8fx0A |
Crystal structure of the trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (hgxprt), isoform d, bound to (s)-serme-immh phosphonate |
115
|
502
|
7yj2B |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
98
|
423
|
7yj2A |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
89
|
423
|
7yj1A |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
5
|
38
|
7yj2E |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
5
|
43
|
7yiuE |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
34
|
153
|
7yiuD |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
6
|
48
|
7yiuC |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
14
|
48
|
7yj2C |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
89
|
423
|
7yiuA |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
13
|
48
|
7yj1C |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
8
|
38
|
7yj1E |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
36
|
143
|
7yj2D |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
36
|
143
|
7yj1D |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
108
|
502
|
7yj1B |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
104
|
499
|
7yiuB |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
95
|
289
|
8g8xA |
X-ray co-crystal structure of compound 27 in with complex jak2 |
97
|
289
|
8g8oA |
The crystal structure of jak2 in complex with compound 31 |
100
|
289
|
8g6zA |
Jak2 crystal structure in complex with compound 13 |
93
|
289
|
7teuA |
Crystal structure of jak2 jh1 with type ii inhibitor yliu-04-105-1 |
63
|
304
|
8stgA |
Discovery and clinical validation of rly-4008, the first highly selective fgfr2 inhibitor with activity across fgfr2 alterations and resistance mutations |
100
|
347
|
8ff8A |
Crystal structure of glycogen synthase kinase 3 beta complexed with 2-[(4-cyanophenyl)amino]-n-(4-phenylpyridin-3-yl)pyrimidine-4-carboxamide |
122
|
426
|
8fbmA |
Crystal structure of cryptosporidium parvum n-myristoyltransferase with bound myristoyl-coa and inhibitor 1 |
129
|
426
|
8fbuA |
Crystal structure of cryptosporidium parvum n-myristoyltransferase with bound myristoyl-coa and compound-2 |
277
|
1255
|
8eykE |
Atomic model of the core modifying region of human fatty acid synthase in complex with tvb-2640 |
277
|
1255
|
8gkcA |
Atomic model of the core modifying region of human fatty acid synthase in complex with tvb-2640 - c2 refinement |
92
|
307
|
8g2fA |
Crystal structure of prmt3 with compound ii710 |
77
|
271
|
7uosA |
Structure of wnk1 inhibitor complex |
75
|
275
|
8f7oA |
Braf kinase in complex with tak580 (tovorafenib) |
81
|
273
|
8f7pA |
Braf kinase in complex with lxh254 (naporafenib) |
139
|
556
|
7tazA |
Crystal structure of hiv-1 reverse transcriptase (rt) in complex with vm-1500a, a non-nucleoside rt inhibitor |
103
|
328
|
8fp1A |
Pkceta kinase domain in complex with compound 2 |
97
|
331
|
8fp3A |
Pkceta kinase domain in complex with compound 11 |
90
|
290
|
8fjzA |
Crystal structure of hpk1 kinase domain t165e,s171e phosphomimetic mutant in complex with 3-{4-[(3r,5s)-3-amino-5-methylpiperidin-1-yl]-6-chloro-7h-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile |
92
|
289
|
8fkoA |
Crystal structure of hpk1 kinase domain t165e,s171e phosphomimetic mutant in complex with 3-{4-[(2s,5r)-5-amino-2-methylpiperidin-1-yl]-6-chloro-7h-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile |