|
87
|
284
|
5i4nA |
Crystal structure of the e596a v617f mutant jak2 pseudokinase domain bound to mg-atp |
|
93
|
304
|
5hznA |
Structure of nvp-aew541 in complex with igf-1r kinase |
|
75
|
285
|
5hx6A |
Crystal structure of rip1 kinase with a benzo[b][1,4]oxazepin-4-one |
|
78
|
292
|
5hq0A |
Ternary complex of human proteins cdk1, cyclin b and cks2, bound to an inhibitor |
|
89
|
300
|
5hx8A |
Jak1 complex with 4-[(4-aminocyclohexyl)amino]-3-(1h-benzimidazol-2-yl)-1h-pyridin-2-one |
|
72
|
311
|
5hvkA |
Crystal structure of limk1 mutant d460n in complex with full-length cofilin-1 |
|
86
|
275
|
5hu9A |
Crystal structure of abl1 in complex with chmfl-074 |
|
80
|
293
|
5horA |
Crystal structure of c-met-m1250t in complex with sar125844. |
|
118
|
328
|
5htcA |
Crystal structure of haspin (gsg2) in complex with bisubstrate inhibitor arc-3372 |
|
81
|
289
|
5ho7A |
Discovery of novel 7-azaindoles as pdk1 inhibitors |
|
115
|
328
|
5htbA |
Crystal structure of haspin (gsg2) in complex with bisubstrate inhibitor arc-3353 |
|
69
|
294
|
5hniX |
Crystal structure of cmet wt with compound 3 |
|
88
|
266
|
5hu3A |
Drosophila camkii-d136n in complex with a phosphorylated fragment of the eag potassium channel and mg2+/adp |
|
103
|
351
|
5hlnA |
X-ray crystal structure of gsk3b in complex with chir99021 |
|
94
|
363
|
5hbjA |
Cdk8-cycc in complex with 8-[2-amino-3-chloro-5-(1-methyl-1h-indazol-5-yl)-pyridin-4-yl]-2,8-diaza-spiro[4.5]decan-1-one |
|
87
|
299
|
5hlwA |
Crystal structure of c-met mutant y1230h in complex with compound 14 |
|
117
|
347
|
5hd4A |
Dissecting therapeutic resistance to erk inhibition rat wild type sch772984 in complex with (3r)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-n-[3-(pyridin-4-yl)-2h-indazol-5-yl]pyrrolidine-3-carboxamide |
|
75
|
269
|
5hieA |
Braf kinase domain b3ac loop deletion mutant in complex with dabrafenib |
|
96
|
305
|
5fxrA |
Igfr-1r complex with a pyrimidine inhibitor. |
|
91
|
294
|
4usfA |
Human slk with sb-440719 |
|
77
|
293
|
4useA |
Human stk10 (lok) with sb-633825 |
|
80
|
280
|
4cvaA |
Mps1 kinase with 3-aminopyridin-2-one inhibitors |
|
96
|
314
|
4ckrA |
Crystal structure of the human ddr1 kinase domain in complex with ddr1-in-1 |
|
101
|
314
|
4ckjA |
Crystal structure of ret tyrosine kinase domain bound to adenosine |
|
100
|
308
|
4cljA |
Structure of l1196m mutant human anaplastic lymphoma kinase in complex with pf-06463922 ((10r)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2h-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile). |
|
129
|
377
|
4cg9A |
Human choline kinase a1 in complex with compound 12 |
|
87
|
324
|
5canA |
Egfr kinase domain mutant "tmlr" with compound 27 |
|
90
|
324
|
5c8nA |
Egfr kinase domain mutant "tmlr" with compound 23 |
|
94
|
290
|
5cf6A |
Crystal structure of janus kinase 2 in complex with n,n-dicyclopropyl-10-[(2s)-2,3-dihydroxypropyl]-3-methyl-7-(methylamino)-3,5,8,10-tetraazatricyclo [7.3.0.02,6]dodeca-1(9),2(6),4,7,11-pentaene-11-carboxamide |
|
89
|
322
|
5calA |
Egfr kinase domain mutant "tmlr" with compound 24 |
|
93
|
275
|
5cxzA |
Syk catalytic domain complexed with naphthyridine inhibitor |
|
85
|
282
|
5ceoA |
Dlk in complex with inhibitor 2-((6-(3,3-difluoropyrrolidin-1-yl)-4-(1-(oxetan-3-yl)piperidin-4-yl)pyridin-2-yl)amino)isonicotinonitrile |
|
92
|
324
|
5casA |
Egfr kinase domain mutant "tmlr" with compound 41a |
|
97
|
292
|
5cf8A |
Crystal structure of janus kinase 2 in complex with n,n-dicyclopropyl-10-ethyl-7-[(3-methoxypropyl)amino] -3-methyl-3,5,8,10-tetraazatricyclo[7.3.0.0,6] dodeca-1(9),2(6),4,7,11-pentaene-11-carboxamide |
|
86
|
282
|
5cepA |
Dlk in complex with inhibitor n-(1-isopropyl-5-(piperidin-4-yl)-1h-pyrazol-3-yl)-4-(trifluoromethyl)pyridin-2-amine |
|
106
|
327
|
5cu0A |
Crystal structure of ck2alpha with 2-hydroxy-5-methylbenzoic acid and n-(3-(3-chloro-4-(phenyl)benzylamino)propyl)acetamide bound |
|
93
|
289
|
5cf4A |
Crystal structure of janus kinase 2 in complex with n,n-dicyclopropyl-10-ethyl-7-[(3-methoxypropyl)amino] -3-methyl-3,5,8,10-tetraazatricyclo[7.3.0.0,6] dodeca-1(9),2(6),4,7,11-pentaene-11-carboxamide |
|
88
|
324
|
5cavA |
Egfr kinase domain with compound 41a |
|
83
|
323
|
5caoA |
Egfr kinase domain mutant "tmlr" with compound 29 |
|
104
|
336
|
5f9eA |
Structure of protein kinase c theta with compound 10: 2,2-dimethyl-7-(2-oxidanylidene-3~{h}-imidazo[4,5-b]pyridin-1-yl)-1-(phenylmethyl)-3~{h}-quinazolin-4-one |
|
78
|
277
|
5cemA |
Pseudokinase and c-terminal extension of human tribbles homolog 1 |
|
91
|
323
|
5cauA |
Egfr kinase domain mutant "tmlr" with compound 41b |
|
94
|
309
|
5fdpA |
Structure of ddr1 receptor tyrosine kinase in complex with d2099 inhibitor at 2.25 angstroms resolution. |
|
108
|
327
|
5cspA |
Crystal structure of ck2alpha with compound 5 bound |
|
98
|
292
|
5cf5A |
Crystal structure of janus kinase 2 in complex with n,n-dicyclopropyl-7-[(dimethyl-1,3-thiazol-2-yl)amino]-10-ethyl-3-methyl-3,5,8,10-tetraazatricyclo[7.3.0.02,6] dodeca-1(9),2(6),4,7,11-pentaene-11-carboxamide |
|
67
|
255
|
5cekA |
Pseudokinase domain of human tribbles homolog 1 |
|
94
|
322
|
5caqA |
Egfr kinase domain mutant "tmlr" with compound 33 |
|
91
|
323
|
5capA |
Egfr kinase domain mutant "tmlr" with compound 30 |
|
99
|
350
|
5eknA |
Crystal structure of mapk13 complex with inhibitor |
|
91
|
308
|
5bvnA |
Fragment-based discovery of potent and selective ddr1/2 inhibitors |
