|
97
|
311
|
3ik1A |
Lactobacillus casei thymidylate synthase in ternary complex with dump and the phtalimidic derivative 20c |
|
156
|
518
|
3iroA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with nadph and q-8 antifolate |
|
161
|
520
|
3irmA |
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase complexed with cycloguanil |
|
96
|
312
|
3ik0A |
Lactobacillus casei thymidylate synthase in ternary complex with dump and the phtalimidic derivative 7c1 |
|
90
|
280
|
3ihiA |
Crystal structure of mouse thymidylate synthase |
|
96
|
312
|
3ijzA |
Lactobacillus casei thymidylate synthase ternary complex with dump and pthalimidic derivative 15c |
|
155
|
506
|
3i3rA |
X-ray structure dihydrofolate reductase/thymidylate synthase from babesia bovis at 2.35a resolution |
|
92
|
281
|
3hb8A |
Structures of thymidylate synthase r163k with substrates and inhibitors show subunit asymmetry |
|
89
|
281
|
3h9kA |
Structures of thymidylate synthase r163k with substrates and inhibitors show subunit asymmetry |
|
157
|
515
|
3hbbA |
Structures of dihydrofolate reductase-thymidylate synthase of trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate |
|
76
|
307
|
3gh0A |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
83
|
283
|
3gg5A |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
81
|
304
|
3gh2X |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
82
|
283
|
3ejlA |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
60
|
285
|
3ef9A |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
71
|
285
|
3ebuA |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
79
|
289
|
3ed7A |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
80
|
285
|
3ehiX |
Crystal structure of human thymidyalte synthase m190k with loop 181-197 stabilized in the inactive conformation |
|
79
|
285
|
3edwX |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
64
|
284
|
3egyX |
Crystal structure of human thymidyalte synthase a191k with loop 181-197 stabilized in the inactive conformation |
|
69
|
285
|
3eawX |
Replacement of val3 in human thymidylate synthase affects its kinetic properties and intracellular stability |
|
103
|
325
|
3dgaC |
Wild-type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with rjf01302, nadph, and dump |
|
63
|
230
|
3dgaA |
Wild-type plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with rjf01302, nadph, and dump |
|
103
|
326
|
3dg8C |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with rjf670, nadph, and dump |
|
58
|
231
|
3dg8A |
Quadruple mutant (n51i+c59r+s108n+i164l) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (pfdhfr-ts) complexed with rjf670, nadph, and dump |
|
153
|
515
|
3clbA |
Structure of bifunctional tcdhfr-ts in complex with tmq |
|
140
|
513
|
3cl9A |
Structure of bifunctional tcdhfr-ts in complex with mtx |
|
99
|
315
|
3byxA |
Lactobacillus casei thymidylate synthase ternary complex with dump and the phtalimidic derivative c00 in multiple binding modes |
|
89
|
312
|
3bz0A |
Lactobacillus casei thymidylate synthase ternary complex with dump and the phtalimidic derivative c00 |
|
90
|
316
|
3c06A |
Lactobacillus casei thymidylate synthase ternary complex with dump and the phtalimidic derivative 14c in multiple binding modes-mode 1 |
|
81
|
313
|
3c0aA |
Lactobacillus casei thymidylate synthase ternary complex with dump and the phtalimidic derivative 14c in multiple binding modes-mode 2 |
|
86
|
263
|
3bhrA |
E. coli ts complexed with 5-no2dump and tetrahydrofolate at 1.9 a resolution (space group 152) |
|
89
|
314
|
3bnzA |
Crystal structure of thymidylate synthase ternary complex with dump and 8a inhibitor |
|
86
|
263
|
3bhlA |
E.coli thymidylate synthase complexes with 5-no2dump and tetrahydrofolate at 1.4 a resolution |
|
86
|
263
|
3bgxA |
E. coli thymidylate synthase c146s mutant complexed with dtmp and mtf |
|
84
|
263
|
3bfiA |
E. coli thymidylate synthase y209m mutant complexed with 5-nitro-dump |
|
85
|
263
|
3b9hA |
E. coli thymidylate synthase complexed with 5-nitro-2'-deoxy uridine |
|
81
|
264
|
3b5bA |
Crystal structure of the thymidylate synthase k48q |
|
83
|
263
|
2vf0A |
Crystal structure of the thymidylate synthase k48q complexed with 5no2dump and bw1843u89 |
|
88
|
264
|
2vetA |
Crystal structure of the thymidylate synthase k48q complexed with dump |
|
84
|
264
|
2tscA |
Structure, multiple site binding, and segmental accomodation in thymidylate synthase on binding d/ump and an anti-folate |
|
104
|
316
|
2tdmA |
Structure of thymidylate synthase |
|
93
|
315
|
2tddA |
Structures of thymidylate synthase with a c-terminal deletion: role of the c-terminus in alignment of d/ump and ch2h4folate |
|
92
|
281
|
2tsrA |
Thymidylate synthase from rat in ternary complex with dump and tomudex |
|
98
|
283
|
2rd8A |
Human thymidylate synthase stabilized in active conformation by r163k mutation: asymmetry and reactivity of cys195 |
|
87
|
282
|
2rdaA |
Human thymidylate synthase stabilized in active conformation by r163k mutation: asymmetry and reactivity of cys195 |
|
86
|
284
|
2rd8B |
Human thymidylate synthase stabilized in active conformation by r163k mutation: asymmetry and reactivity of cys195 |
|
72
|
285
|
2onbA |
Human thymidylate synthase at low salt conditions with pdpa bound |
|
166
|
519
|
2oipA |
Crystal structure of the s290g active site mutant of ts-dhfr from cryptosporidium hominis |
|
77
|
264
|
2kceA |
Binding of the anticancer drug zd1694 to e. coli thymidylate synthase: assessing specificity and affinity |
