|
251
|
664
|
1uvmA |
The structural basis for rna specificity and ca2 inhibition of an rna-dependent rna polymerase phi6p2 with 5nt rna conformation a |
|
235
|
664
|
4a8fA |
Non-catalytic ions direct the rna-dependent rna polymerase of bacterial dsrna virus phi6 from de novo initiation to elongation |
|
234
|
664
|
4a8kA |
Non-catalytic ions direct the rna-dependent rna polymerase of bacterial dsrna virus phi6 from de novo initiation to elongation |
|
233
|
664
|
4a8sA |
Non-catalytic ions direct the rna-dependent rna polymerase of bacterial dsrna virus phi6 from de novo initiation to elongation |
|
235
|
664
|
4a8wA |
Non-catalytic ions direct the rna-dependent rna polymerase of bacterial dsrna virus phi6 from de novo initiation to elongation |
|
236
|
664
|
4a8yA |
Non-catalytic ions direct the rna-dependent rna polymerase of bacterial dsrna virus phi6 from de novo initiation to elongation |
|
237
|
664
|
4a8qA |
Non-catalytic ions direct the rna-dependent rna polymerase of bacterial dsrna virus phi6 from de novo initiation to elongation |
|
230
|
664
|
2jlgA |
Structural explanation for the role of mn in the activity of phi6 rna-dependent rna polymerase |
|
200
|
562
|
4eo6A |
Hcv ns5b polymerase inhibitors: tri-substituted acylhydrazines as tertiary amide bioisosteres |
|
203
|
562
|
4eo8A |
Hcv ns5b polymerase inhibitors: tri-substituted acylhydrazines as tertiary amide bioisosteres |
|
193
|
563
|
4druA |
Hcv ns5b in complex with macrocyclic indole inhibitor |
|
209
|
562
|
4eawA |
Hcv ns5b in complex with idx375 |
|
199
|
544
|
4e76A |
Apo crystal structure of hcv ns5b genotype 2a jfh-1 isolate with beta hairpin loop deletion |
|
236
|
664
|
4b02A |
The c-terminal priming domain is strongly associated with the main body of bacteriophage phi6 rna-dependent rna polymerase |
|
216
|
563
|
4aexA |
Hcv-jfh1 ns5b polymerase structure at 2.4 angstrom in a primitive orthorhombic space group |
|
269
|
766
|
3zedA |
X-ray structure of the birnavirus vp1-vp3 complex |
|
214
|
564
|
4adpA |
Hcv-j6 ns5b polymerase v405i mutant |
|
235
|
664
|
4a8oA |
Non-catalytic ions direct the rna-dependent rna polymerase of bacterial dsrna virus phi6 from de novo initiation to elongation |
|
211
|
563
|
4aepA |
Hcv-jfh1 ns5b polymerase structure at 1.8 angstrom |
|
1
|
12
|
3zedD |
X-ray structure of the birnavirus vp1-vp3 complex |
|
201
|
553
|
3vqsA |
Crystal structure of hcv ns5b rna polymerase with a novel piperazine inhibitor |
|
27
|
89
|
3vcbA |
C425s mutant of the c-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus a59 |
|
28
|
81
|
3vc8A |
Crystal structure of the c-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus a59 |
|
207
|
563
|
3u4rA |
Novel hcv ns5b polymerase inhibitors: discovery of indole c2 acyl sulfonamides |
|
203
|
568
|
3u4oA |
Novel hcv ns5b polymerase inhibitors: discovery of indole c2 acyl sulfonamides |
|
202
|
568
|
3upiA |
Synthesis of novel 4,5-dihydrofurano indoles and their evaluation as hcv ns5b polymerase inhibitors |
|
201
|
568
|
3uphA |
Synthesis of novel 4,5-dihydrofurano indoles and their evaluation as hcv ns5b polymerase inhibitors |
|
209
|
568
|
3tyqA |
Sar development and discovery of potent indole-based inhibitors of the hepatitis c virus ns5b polymerase |
|
204
|
568
|
3tyvA |
Sar development and discovery of potent indole-based inhibitors of the hepatitis c virus ns5b polymerase |
|
193
|
573
|
5pznA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 5-[3-(tert-butylcarbamoyl)phenyl]-2-(4-fluorophenyl)-n-methyl-1-benzofuran-3-carboxamide |
|
192
|
573
|
5pzmA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 3-[2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-5-yl]benzoic acid |
|
195
|
573
|
5pzlA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-({3-[1-(2-cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-1,1-dioxo-1,4-dihydro-1lambda~6~,2,4-benzothiadiazin-7-yl}oxy)acetamide |
|
193
|
573
|
5pzoA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase c316n in complex with 2-(4-fluorophenyl)-n-methyl-5-[3-({2-methyl-1-oxo-1-[(1,3,4-thiadiazol-2-yl)amino]propan-2-yl}carbamoyl)phenyl]-1-benzofuran-3-carboxamide |
|
191
|
573
|
5pzpA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 4-fluoro-2-(4-fluorophenyl)-n-methyl-5-(2-methyl-5-{[1-(pyrimidin-2-yl)cyclopropyl]carbamoyl}phenyl)-1-benzofuran-3-carboxamide (bms-929075) |
|
188
|
563
|
5pzkA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase in complex with 2-(4-fluorophenyl)-n-methyl-6-[(methylsulfonyl)amino]-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide |
|
177
|
664
|
5fj6A |
Structure of the p2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex |
|
147
|
462
|
4zpaA |
Coxsackievirus b3 polymerase - f364y mutant |
|
147
|
462
|
4zpdA |
Coxsackievirus b3 polymerase - a345v mutant |
|
148
|
462
|
4zpbA |
Coxsackievirus b3 polymerase - f364w mutant |
|
141
|
462
|
4wfxA |
Coxsackievirus b3 polymerase - f232l mutant - nacl crystal form |
|
203
|
544
|
4wt9A |
Apo crystal structure of hcv ns5b genotype 2a jfh-1 isolate with e86q e87q s15g c223h v321i and delta8 mutations |
|
146
|
462
|
4wfyA |
Coxsackievirus b3 polymerase - f232l mutant - amso4 crystal form |
|
146
|
462
|
4wfzA |
Coxsackievirus b3 3dpol rna dependent rna polymerase - nacl crystal form |
|
141
|
461
|
4r0eA |
Crystal structure of the poliovirus rna-dependent rna polymerase low-fidelity mutant 3dpol h273r |
|
198
|
562
|
4oowA |
Hcv ns5b polymerase with a fragment of quercetagetin |
|
206
|
562
|
4mk8A |
Hepatitis c virus polymerase ns5b genotype 1b (bk) in complex with inhibitor 4 (n-(4-{2-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]ethyl}phenyl)methanesulfonamide) |
|
206
|
568
|
4mz4A |
Discovery of an irreversible hcv ns5b polymerase inhibitor |
|
166
|
505
|
4nldA |
Crystal structure of the hepatitis c virus ns5b rna-dependent rna polymerase complex with bms-791325 also known as (1ar,12bs)-8-cyclohexyl-n-(dimethylsulfamoyl)-11-methoxy-1a-{[(1r,5s)-3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl]carbonyl}-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide and 2-(4-fluorophenyl)-n-methyl-6-[(me |
|
200
|
554
|
4obcA |
Crystal structure of hcv polymerase ns5b genotype 2a jfh-1 isolate with the s15g, c223h, v321i resistance mutations against the guanosine analog gs-0938 (psi-3529238) |
|
204
|
562
|
4mkaA |
Hepatitis c virus polymerase ns5b genotype 1b (bk) in complex with inhibitor 13 (n-{2-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]-1,3-benzoxazol-5-yl}methanesulfonamide) |
