|
217
|
545
|
7louA |
Crystal structure of clostridium difficile toxin b (tcdb) glucosyltransferase in complex with udp and isofagomine |
|
42
|
154
|
7lqpA |
Rapid development of potent inhibitors of the hiv integrase-ledgf interaction by fragment-linking using off-rate screening |
|
155
|
556
|
7lpxA |
Crystal structure of hiv-1 rt in complex with nbd-14270 |
|
86
|
291
|
8tucA |
Unphosphorylated camkk2 in complex with cc-8977 |
|
128
|
361
|
7vbuA |
Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 5 |
|
115
|
333
|
8g2hA |
Crystal structure of prmt4 with compound yd1113 |
|
85
|
275
|
7kp6A |
Structure of ack1 kinase in complex with a selective inhibitor |
|
99
|
266
|
7tz7B |
Pi3k alpha in complex with an inhibitor |
|
60
|
261
|
7t7mA |
Structure of human glp set-domain (ehmt1) in complex with covalent inhibitor (compound 1) |
|
85
|
273
|
7t0pA |
Jak2 jh2 in complex with jak315 |
|
137
|
403
|
7tevA |
Human ornithine aminotransferase cocrystallized with its inhibitor, (3s,4r)-3-amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylate |
|
133
|
404
|
7tedA |
Human ornithine aminotransferase cocrystallized with its inhibitor, (s,e)-3-amino-4-(fluoromethylene)cyclopent-1-ene-1-carboxylate |
|
281
|
940
|
7mlkA |
Crystal structure of human pi3ka (p110a subunit) with mmv085400 bound to the active site determined at 2.9 angstroms resolution |
|
91
|
332
|
7n93A |
P70 s6k1 in complex with msc2363318a-1 |
|
90
|
270
|
7mu7A |
Ask1 bound to compound 3 |
|
96
|
334
|
7n91A |
P70 s6k1 in complex with msc2317067a-1 |
|
128
|
394
|
7ei4A |
Crystal structure of masl in complex with a novel covalent inhibitor, collimonin c |
|
296
|
835
|
8fg8A |
Catalytic domain of gtfb in complex with inhibitor 2-[(2,4,5-trihydroxyphenyl)methylidene]-1-benzofuran-3-one |
|
165
|
462
|
8fjtA |
Human mitochondrial serine hydroxymethyltransferase (shmt2) in complex with plp, glycine and agf362 inhibitor |
|
148
|
462
|
8fjuA |
Human mitochondrial serine hydroxymethyltransferase (shmt2) in complex with plp, glycine and agf347 inhibitor |
|
118
|
385
|
8fbqA |
Crystal structure of plasmodium vivax glycylpeptide n-tetradecanoyltransferase (n-myristoyltransferase, nmt) bound to myristoyl-coa and inhibitor 12b |
|
88
|
322
|
8g63A |
Ralimetinib (ly2228820) in complex with wild type egfr |
|
79
|
209
|
7xbaA |
Glutathione s-transferase bound with a covalent inhibitor |
|
88
|
246
|
8s9mA |
Dna cytosine-n4 methyltransferase (residues 79-324) from the bdelloid rotifer adineta vaga |
|
85
|
258
|
8s9oA |
Dna cytosine-n4 methyltransferase (residues 61-324) from the bdelloid rotifer adineta vaga - p1 crystal form |
|
81
|
257
|
8s9nA |
Dna cytosine-n4 methyltransferase (residues 61-324) from the bdelloid rotifer adineta vaga - c2 crystal form |
|
62
|
222
|
8fx1A |
Crystal structure of the trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (hgxprt), isoform d, bound to (r)-serme-immh phosphonate |
|
63
|
222
|
8fwzA |
Crystal structure of the trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (hgxprt), isoform d, bound to hydroxypropyl-lin-immh phosphonate |
|
62
|
222
|
8fx0A |
Crystal structure of the trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (hgxprt), isoform d, bound to (s)-serme-immh phosphonate |
|
63
|
223
|
8fx3A |
Crystal structure of the trypanosoma cruzi hypoxanthine-guanine-xanthine phosphoribosyltransferase (hgxprt), isoform d, bound to immucillin-gp, showing the structure of the complete active site in its open conformation |
|
115
|
502
|
7yj2B |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
|
98
|
423
|
7yj2A |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
|
5
|
38
|
7yj2E |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
|
89
|
423
|
7yj1A |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
|
5
|
43
|
7yiuE |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
|
34
|
153
|
7yiuD |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
|
6
|
48
|
7yiuC |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
|
14
|
48
|
7yj2C |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
|
36
|
143
|
7yj2D |
Cryo-em structure of spt-ormdl3 (ormdl3-n13a) complex |
|
89
|
423
|
7yiuA |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
|
13
|
48
|
7yj1C |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
|
8
|
38
|
7yj1E |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
|
36
|
143
|
7yj1D |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
|
108
|
502
|
7yj1B |
Cryo-em structure of spt-ormdl3 (ormdl3-deltan2) complex |
|
104
|
499
|
7yiuB |
Cryo-em structure of the c6-ceramide-bound spt-ormdl3 complex |
|
95
|
289
|
8g8xA |
X-ray co-crystal structure of compound 27 in with complex jak2 |
|
100
|
289
|
8g6zA |
Jak2 crystal structure in complex with compound 13 |
|
97
|
289
|
8g8oA |
The crystal structure of jak2 in complex with compound 31 |
|
93
|
289
|
7teuA |
Crystal structure of jak2 jh1 with type ii inhibitor yliu-04-105-1 |
|
63
|
304
|
8stgA |
Discovery and clinical validation of rly-4008, the first highly selective fgfr2 inhibitor with activity across fgfr2 alterations and resistance mutations |
