|
76
|
271
|
5sx8B |
Crystal structure of pi3kalpha in complex with fragments 12 and 15 |
|
85
|
272
|
5swgB |
Crystal structure of pi3kalpha in complex with fragments 5 and 21 |
|
56
|
270
|
5sw8B |
Crystal structure of pi3kalpha in complex with fragments 7 and 11 |
|
24
|
103
|
5kazA |
Human sh2d1b structure |
|
160
|
522
|
5ibsA |
Structure of e76q, a cancer-associated mutation of the oncogenic phosphatase shp2 |
|
24
|
97
|
5gjhA |
Gads sh2 domain/cd28-derived peptide complex |
|
129
|
447
|
5h0bA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor (s)-2-(((1r,4s)-4-(4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-4-methylpentanoic acid |
|
127
|
447
|
5h09A |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor (s)-ethyl2-(((1r,4s)-4-(4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-4-methylpentanoate |
|
28
|
107
|
5gjiA |
Pi3k p85 n-terminal sh2 domain/cd28-derived peptide complex |
|
129
|
447
|
5h0hA |
Crystal structure of hck complexed with a pyrrolo-pyrimidine inhibitor (s)-2-(((1r,4s)-4-(4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-n,n,4-trimethylpentanamide |
|
33
|
109
|
5aulA |
Pi3k p85 c-terminal sh2 domain/cd28-derived peptide complex |
|
97
|
263
|
5fi4B |
Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-pi3 kinases that are efficacious in a mouse xenograft model |
|
163
|
523
|
5ehpA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp836 |
|
26
|
104
|
5eelA |
Grb7 sh2 with bicyclic peptide inhibitor |
|
26
|
113
|
5eg3B |
Crystal structure of the activated fgf receptor 2 (fgfr2) kinase domain in complex with the csh2 domain of phospholipase c gamma (plcgamma) |
|
156
|
522
|
5ehrA |
Non-receptor protein tyrosine phosphatase shp2 in complex with allosteric inhibitor shp099 |
|
27
|
103
|
5eeqA |
Grb7 sh2 with the g7-b1 bicyclic peptide inhibitor |
|
23
|
98
|
5dc0B |
Crystal structure of monobody gg3/abl1 sh2 domain complex |
|
28
|
100
|
5dc4A |
Crystal structure of monobody as25/abl1 sh2 domain complex, crystal a |
|
56
|
217
|
5df6A |
Crystal structure of ptpn11 tandem sh2 domains in complex with a txnip peptide |
|
27
|
100
|
5dc9A |
Crystal structure of monobody as25/abl1 sh2 domain complex, crystal b |
|
23
|
106
|
5d0jA |
Grb7 sh2 with inhibitor peptide |
|
105
|
444
|
4xi2A |
Crystal structure of an auto-inhibited form of bruton's tryrosine kinase |
|
63
|
254
|
4xz1A |
Zap-70-tsh2:compound-b adduct |
|
122
|
522
|
4y5uA |
Transcription factor |
|
84
|
273
|
4xeyA |
Crystal structure of an sh2-kinase domain construct of c-abl tyrosine kinase |
|
70
|
258
|
4xz0A |
Zap-70-tsh2:compound-a complex |
|
29
|
112
|
4wwqA |
Apo structure of the grb7 sh2 domain |
|
90
|
267
|
4wafB |
Crystal structure of a novel tetrahydropyrazolo[1,5-a]pyrazine in an engineered pi3k alpha |
|
25
|
106
|
4x6sA |
Grb7 sh2 domain with phosphotyrosine mimetic inhibitor peptide |
|
26
|
110
|
4tziA |
Structure of unliganded lyn sh2 domain |
|
26
|
103
|
4rojA |
Crystal structure of the vav2 sh2 domain in complex with txnip phosphorylated peptide |
|
26
|
113
|
4u1pA |
Human fyn-sh2 domain in complex with a synthetic high-affinity phospho-peptide |
|
21
|
102
|
4u17A |
Swapped dimer of the human fyn-sh2 domain |
|
37
|
163
|
4u5wB |
Crystal structure of hiv-1 nef-sf2 core domain in complex with the src family kinase hck sh3-sh2 tandem regulatory domains |
|
25
|
100
|
4qsyA |
Shp2 sh2 domain in complex with gab1 peptide |
|
64
|
272
|
4ovvB |
Crystal structure of pi3kalpha in complex with dic4-pip2 |
|
21
|
100
|
4p9vA |
Grb2 sh2 complexed with a ptyr-ac6cn-asn tripeptide |
|
25
|
109
|
4p9zA |
Grb2 sh2 complexed with a ptyr-ac6c-asn tripeptide |
|
81
|
272
|
4ovuB |
Crystal structure of p110alpha in complex with nish2 of p85alpha |
|
158
|
526
|
4ohiA |
Leopard syndrome-associated shp2/q510e mutant |
|
144
|
524
|
4ohlA |
Leopard syndrome-associated shp2/t468m mutant |
|
158
|
531
|
4nwfA |
Crystal structure of the tyrosine phosphatase shp-2 with n308d mutation |
|
154
|
526
|
4oheA |
Leopard syndrome-associated shp2/g464a mutant |
|
150
|
526
|
4ohhA |
Leopard syndrome-associated shp2/q506p mutant |
|
155
|
533
|
4nwgA |
Crystal structure of the tyrosine phosphatase shp-2 with e139d mutation |
|
145
|
526
|
4ohdA |
Leopard syndrome-associated shp2/a461t mutant |
|
112
|
446
|
4lueA |
Crystal structure of hck in complex with 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine (resulting from displacement of skf86002) |
|
106
|
447
|
4ludA |
Crystal structure of hck in complex with the fluorescent compound skf86002 |
|
36
|
158
|
4m4zA |
Sh3 and sh2 domains of human src-like adaptor protein 2 (slap2) |
