4WWQA

Apo structure of the grb7 sh2 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
112
structure length
112
Chain Sequence
LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
molecule tags Signaling protein
molecule keywords Growth factor receptor-bound protein 7
publication title Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
pubmed doi rcsb
source organism Homo sapiens
total genus 29
structure length 112
sequence length 112
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4wwqA00
2AOBA 2EYZA 1O41A 1SHBA 4H34A 3C7IA 1BFIA 2LNWA 1O4NA 2BBUA 3BUWB 1O48A 5IBSA 1X27A 3VROA 3S8OA 1RPYA 1JYQA 1A07A 1R1PA 1BLJA 2ECDA 4GWFA 4QSYA 5I6VA 5EHPA 3IN8A 2C0OA 2KK6A 3VRNA 3VS7A 3K2MA 4XZ0A 1AB2A 2GE9A 3VS4A 1FBVA 1O4MA 5EELA 2HDXA 3KFJA 2ABLA 2DX0A 3GXXA 4P9ZA 1KA6A 2LQNA 1BG1A 2IUIA 5DC9A 5EEQA 1KC2A 3CD3A 3BUXB 2MK2A 3M7FA 1OO4A 4E68A 2EKXA 4NWGA 2CBLA 5GJHA 1JYRA 2C0TA 5BO4A 1A81A 2B3OA 1BHHB 2C0IA 1AYDA 2EOBA 4DGXA 2CRHA 3OB1B 2OZOA 4A4CA 2ETZA 5GJIA 3TL0A 3MXYA 4DGPA 3MXCA 1Y1UA 2AUGA 2LCTA 1KSWA 1O44A 5J3XA 5CDWA 1LCJA 1UUSA 1BHFA 4K44A 1RQQC 5HKZA 2Y3AB 3VS0A 1UURA 3BKBA 3HCKA 5DC4A 3VRPA 3HIZB 1SPRA 1BMBA 2Y1NA 4XZ1A 1SKJA 1Y57A 1HCTB 2HUWA 2RMXA 1B47A 1D4TA 3HHMB 2DVJA 1X0NA 1NRVA 2MC1A 3VRYA 1A1AA 1YVHA 3BUOB 1MW4A 1BKMA 2CI8A 1CSYA 3VS1A 2DM0A 1D4WA 1LUIA 1OPKA 2PTKA 4K2RA 4OHIA 1O49A 2DCRA 4GL9E 4LUDA 5HKYA 3VS6A 4FL2A 4GPLB 1O4DA 1IJRA 3PQZA 1F2FA 2IUGA 1H9OA 4FL3A 2DLYA 2EYVA 5KAZA 4E93A 2L4KA 5HKWA 1OO3A 1SHAA 1A1EA 3UYOA 2PNAA 4K45A 1O4JA 1O4BA 1FBZA 4JE4A 3PSJA 1P13A 1GRIA 3UF4A 1O4LA 1AOTF 1JU5A 3N84A 2PNBA 1AD5A 4EIHA 2L6KA 2EO3A 3PS5A 1O46A 3GQIB 5IBMA 2H8HA 2JYQA 1FMKA 4OHHA 3TKZA 3VS5A 1SPSA 1BF5A 1A1CA 3NHNA 3IMDA 1WQUA 1LKKA 2HDVA 2RVFA 1BFJA 1O43A 2K79B 4JGHA 1LUNA 1FU6A 1OPLA 2H5KA 2DLZA 4TZIA 2SHPA 1JYUA 1F1WA 4U17A 5DF6A 1M27A 3US4A 1YVLA 2OQ1A 3PFVA 1AYAA 1FU5A 1O4IA 1TZEE 1O4GA 3CXLA 3S8NA 1LUMA 3EACA 3OVEA 2KNOA 2CS0A 1KA7A 3MAZA 4ROJA 1A09A 1M61A 1CWEA 4P9VA 1JWOA 2PLEA 3VRZA 4F5BA 1FYRA 4EY0A 1BLKA 1O4FA 1MILA 2CR4A 5EG3B 1R1QA 2XP1A 4K11A 1QG1E 1PICA 3GXWA 2HMHA 1O4CA 1QADA 2YU7A 1AYCA 1O4HA 5EHRA 2CIAA 1LKLA 2H46E 4M4ZA 1O42A 4H1OA 4X6SA 5AXIA 3VS3A 4A4BA 2IZVA 4F5AA 1O4PA 3VRRA 1NZVA 1O4RA 3N7YA 1O47A 3PJPA 3CWGA 5D0JA 1BM2A 1AYBA 3T04A 1A1BA 3OB2B 4OHEA 2LQWA 3PLFB 1CSZA 3BUNB 2MRKA 3WA4A 1XA6A 1FHSA 2MRJA 5AULA 4JEGA 4WWQA 2RORA 4OHLA 1O4AA 1K9AA 1SHDA 4NWFA 1ZFPE 4OHDA 1LCKA 2Y1MA 4LUEA 2LNXA 3S8LA 2MQIA 3IN7A 3OV1A 2C9WA 1IS0A 1I3ZA 1QCFA 1O4EA 3BUMB 2HCKA 2K7AB 3PSKA 3VGOA 1A08A 4FBNA 3S9KA 1CJ1A 2EU0A 1LUKA 3VS2A 2EO6A 1TCEA 3ZNIA 1BHHA 2L3TA 2CI9A 1G83A 2YSXA 2EL8A 4U1PA 3IMJA 3QWXX 1BKLA 1GHUA 2EYYA 2IUHA 1CWDL 4F59A 2RSYA 1X6CA 1Z3KA 4L1BB 2VIFA 2FCIA 3N8MA 2GSBA 1AOUF 1R1SA 1NZLA 5DC0B 1O4QA 2AOAA 2FO0A 3EAZA 1RJAA 2QMSA 1D1ZA 1HCSB 4D8KA 2PLDA 3CBLA 3VRQA 2SRCA 1O4KA 1O45A 3OP0A 3QWYA 1O4OA
chains in the Genus database with same CATH superfamily
2AOBA 2EYZA 1O41A 1SHBA 4H34A 3C7IA 1BFIA 2LNWA 1O4NA 2BBUA 3BUWB 1O48A 5IBSA 1X27A 3VROA 3S8OA 1RPYA 1JYQA 1A07A 1R1PA 1BLJA 2ECDA 4GWFA 4QSYA 5I6VA 5EHPA 3IN8A 2C0OA 2KK6A 3VRNA 3VS7A 3K2MA 4XZ0A 1AB2A 2GE9A 3VS4A 1FBVA 1O4MA 5EELA 2HDXA 3KFJA 2ABLA 2DX0A 3GXXA 4P9ZA 1KA6A 2LQNA 1BG1A 2IUIA 5DC9A 5EEQA 1KC2A 3CD3A 3BUXB 2MK2A 3M7FA 2KGYA 1OO4A 4E68A 2EKXA 4NWGA 2CBLA 5GJHA 1JYRA 2C0TA 5BO4A 1A81A 2B3OA 1BHHB 2C0IA 1AYDA 2EOBA 4DGXA 2CRHA 3OB1B 2OZOA 4A4CA 2ETZA 3LYVA 5GJIA 3TL0A 3MXYA 4DGPA 3MXCA 1Y1UA 2AUGA 2LCTA 1KSWA 1O44A 5J3XA 5CDWA 1LCJA 1UUSA 1BHFA 4K44A 1RQQC 5HKZA 2Y3AB 3VS0A 1UURA 3BKBA 3HCKA 5DC4A 3VRPA 3HIZB 1SPRA 1BMBA 2Y1NA 4XZ1A 1SKJA 1Y57A 1HCTB 2HUWA 2RMXA 1B47A 1D4TA 3HHMB 2DVJA 1X0NA 1NRVA 2MC1A 3VRYA 1A1AA 1YVHA 3BUOB 1MW4A 1BKMA 2CI8A 1CSYA 3VS1A 2DM0A 1D4WA 1LUIA 1OPKA 2PTKA 4K2RA 4OHIA 1O49A 2DCRA 4GL9E 4LUDA 5HKYA 3VS6A 4FL2A 4GPLB 1O4DA 1IJRA 3PQZA 1F2FA 2IUGA 1H9OA 4FL3A 2DLYA 2EYVA 5KAZA 4E93A 2L4KA 5HKWA 1OO3A 1SHAA 1A1EA 3UYOA 2PNAA 4K45A 1O4JA 1O4BA 1FBZA 4JE4A 3PSJA 1P13A 1GRIA 3UF4A 1O4LA 1AOTF 1JU5A 3N84A 2PNBA 1AD5A 4EIHA 2L6KA 2EO3A 3PS5A 1O46A 3GQIB 5IBMA 2H8HA 2JYQA 1FMKA 4OHHA 3TKZA 3VS5A 1SPSA 1BF5A 1A1CA 3NHNA 3IMDA 1WQUA 1LKKA 2HDVA 2RVFA 1BFJA 1O43A 2K79B 4JGHA 1LUNA 1FU6A 1OPLA 2H5KA 2DLZA 4TZIA 2SHPA 1JYUA 1F1WA 4U17A 5DF6A 1M27A 3US4A 1YVLA 2OQ1A 3PFVA 1AYAA 1FU5A 1O4IA 1TZEE 1O4GA 3CXLA 3S8NA 1LUMA 3EACA 3OVEA 2KNOA 2CS0A 1KA7A 3MAZA 4ROJA 1A09A 1M61A 1CWEA 4P9VA 1JWOA 2PLEA 3VRZA 4F5BA 1FYRA 4EY0A 1BLKA 1O4FA 1MILA 2CR4A 5EG3B 1R1QA 2XP1A 4K11A 1QG1E 1PICA 3GXWA 2HMHA 1O4CA 1QADA 2YU7A 1AYCA 1O4HA 5EHRA 2CIAA 1LKLA 2H46E 4M4ZA 1O42A 4H1OA 4X6SA 5AXIA 3VS3A 4A4BA 2IZVA 4F5AA 1O4PA 3VRRA 1NZVA 1O4RA 3N7YA 1O47A 3PJPA 3CWGA 1BM2A 5D0JA 1AYBA 3T04A 1A1BA 3OB2B 4OHEA 2LQWA 2LRAA 3PLFB 1CSZA 3BUNB 2MRKA 3WA4A 1XA6A 1FHSA 2MRJA 5AULA 4JEGA 4WWQA 2RORA 4OHLA 1O4AA 1K9AA 1SHDA 4NWFA 1ZFPE 4OHDA 3K2TA 1LCKA 2Y1MA 4LUEA 2LNXA 3S8LA 2MQIA 3IN7A 3OV1A 2C9WA 1IS0A 1I3ZA 1QCFA 1O4EA 3BUMB 2HCKA 2K7AB 3PSKA 3VGOA 1A08A 4FBNA 3S9KA 1CJ1A 2EU0A 1LUKA 3VS2A 2EO6A 1TCEA 3ZNIA 1BHHA 2L3TA 2CI9A 1G83A 2YSXA 2EL8A 4U1PA 3IMJA 3QWXX 1BKLA 1GHUA 2EYYA 2IUHA 1CWDL 4F59A 2RSYA 1X6CA 1Z3KA 4L1BB 2VIFA 2FCIA 3N8MA 2GSBA 1AOUF 1R1SA 1NZLA 5DC0B 1O4QA 2AOAA 2FO0A 3EAZA 1RJAA 2QMSA 1D1ZA 1HCSB 4D8KA 2PLDA 3CBLA 3VRQA 2SRCA 1O4KA 1O45A 3OP0A 3QWYA 1O4OA
chains in the Genus database with same CATH topology
2AOBA 2EYZA 1O41A 1SHBA 4H34A 3C7IA 1BFIA 2LNWA 1O4NA 2BBUA 3BUWB 1O48A 5IBSA 1X27A 3VROA 3S8OA 1RPYA 1JYQA 1A07A 1R1PA 1BLJA 2ECDA 4GWFA 4QSYA 5I6VA 5EHPA 3IN8A 2C0OA 2KK6A 3VRNA 3VS7A 3K2MA 4XZ0A 1AB2A 2GE9A 3VS4A 1FBVA 1O4MA 5EELA 2HDXA 3KFJA 2ABLA 2DX0A 3GXXA 4P9ZA 1KA6A 2LQNA 1BG1A 2IUIA 5DC9A 5EEQA 1KC2A 3CD3A 3BUXB 2MK2A 3M7FA 1OO4A 4E68A 2EKXA 4NWGA 2CBLA 5GJHA 1JYRA 2C0TA 5BO4A 1A81A 2B3OA 1BHHB 2C0IA 1AYDA 2EOBA 4DGXA 2CRHA 3OB1B 2OZOA 4A4CA 2ETZA 5GJIA 3TL0A 3MXYA 4DGPA 3MXCA 1Y1UA 2AUGA 2LCTA 1KSWA 1O44A 5J3XA 5CDWA 1LCJA 1UUSA 1BHFA 4K44A 1RQQC 5HKZA 2Y3AB 3VS0A 1UURA 3BKBA 3HCKA 5DC4A 3VRPA 3HIZB 1SPRA 1BMBA 2Y1NA 4XZ1A 1SKJA 1Y57A 1HCTB 2HUWA 2RMXA 1B47A 1D4TA 3HHMB 2DVJA 1X0NA 1NRVA 2MC1A 3VRYA 1A1AA 1YVHA 3BUOB 1MW4A 1BKMA 2CI8A 1CSYA 3VS1A 2DM0A 1D4WA 1LUIA 1OPKA 2PTKA 4K2RA 4OHIA 1O49A 2DCRA 4GL9E 4LUDA 5HKYA 3VS6A 4FL2A 4GPLB 1O4DA 1IJRA 3PQZA 1F2FA 2IUGA 1H9OA 4FL3A 2DLYA 2EYVA 5KAZA 4E93A 2L4KA 5HKWA 1OO3A 1SHAA 1A1EA 3UYOA 2PNAA 4K45A 1O4JA 1O4BA 1FBZA 4JE4A 3PSJA 1P13A 1GRIA 3UF4A 1O4LA 1AOTF 1JU5A 3N84A 2PNBA 1AD5A 4EIHA 2L6KA 2EO3A 3PS5A 1O46A 3GQIB 5IBMA 2H8HA 2JYQA 1FMKA 4OHHA 3TKZA 3VS5A 1SPSA 1BF5A 1A1CA 3NHNA 3IMDA 1WQUA 1LKKA 2HDVA 2RVFA 1BFJA 1O43A 2K79B 4JGHA 1LUNA 1FU6A 1OPLA 2H5KA 2DLZA 4TZIA 2SHPA 1JYUA 1F1WA 4U17A 5DF6A 1M27A 3US4A 1YVLA 2OQ1A 3PFVA 1AYAA 1FU5A 1O4IA 1TZEE 1O4GA 3CXLA 3S8NA 1LUMA 3EACA 3OVEA 2KNOA 2CS0A 1KA7A 3MAZA 4ROJA 1A09A 1M61A 1CWEA 4P9VA 1JWOA 2PLEA 3VRZA 4F5BA 1FYRA 4EY0A 1BLKA 1O4FA 1MILA 2CR4A 5EG3B 1R1QA 2XP1A 4K11A 1QG1E 1PICA 3GXWA 2HMHA 1O4CA 1QADA 2YU7A 1AYCA 1O4HA 5EHRA 2CIAA 1LKLA 2H46E 4M4ZA 1O42A 4H1OA 4X6SA 5AXIA 3VS3A 4A4BA 2IZVA 4F5AA 1O4PA 3VRRA 1NZVA 1O4RA 3N7YA 1O47A 3PJPA 3CWGA 5D0JA 1BM2A 1AYBA 3T04A 1A1BA 3OB2B 4OHEA 2LQWA 3PLFB 1CSZA 3BUNB 2MRKA 3WA4A 1XA6A 1FHSA 2MRJA 5AULA 4JEGA 4WWQA 2RORA 4OHLA 1O4AA 1K9AA 1SHDA 4NWFA 1ZFPE 4OHDA 1LCKA 2Y1MA 4LUEA 2LNXA 3S8LA 2MQIA 3IN7A 3OV1A 2C9WA 1IS0A 1I3ZA 1QCFA 1O4EA 3BUMB 2HCKA 2K7AB 3PSKA 3VGOA 1A08A 4FBNA 3S9KA 1CJ1A 2EU0A 1LUKA 3VS2A 2EO6A 1TCEA 3ZNIA 1BHHA 2L3TA 2CI9A 1G83A 2YSXA 2EL8A 4U1PA 3IMJA 3QWXX 1BKLA 1GHUA 2EYYA 2IUHA 1CWDL 4F59A 2RSYA 1X6CA 1Z3KA 4L1BB 2VIFA 2FCIA 3N8MA 2GSBA 1AOUF 1R1SA 1NZLA 5DC0B 1O4QA 2AOAA 2FO0A 3EAZA 1RJAA 2QMSA 1D1ZA 1HCSB 4D8KA 2PLDA 3CBLA 3VRQA 2SRCA 1O4KA 1O45A 3OP0A 3QWYA 1O4OA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2AOB A;  2EYZ A;  1O41 A;  1SHB A;  4H34 A;  3C7I A;  1BFI A;  2LNW A;  1O4N A;  2BBU A;  3BUW B;  1O48 A;  5IBS A;  1X27 A;  3VRO A;  3S8O A;  1RPY A;  1JYQ A;  1A07 A;  1R1P A;  1BLJ A;  2ECD A;  4GWF A;  4QSY A;  5I6V A;  5EHP A;  3IN8 A;  2C0O A;  2KK6 A;  3VRN A;  3VS7 A;  3K2M A;  4XZ0 A;  1AB2 A;  2GE9 A;  3VS4 A;  1FBV A;  1O4M A;  5EEL A;  2HDX A;  3KFJ A;  2ABL A;  2DX0 A;  3GXX A;  4P9Z A;  1KA6 A;  2LQN A;  1BG1 A;  2IUI A;  5DC9 A;  5EEQ A;  1KC2 A;  3CD3 A;  3BUX B;  2MK2 A;  3M7F A;  1OO4 A;  4E68 A;  2EKX A;  4NWG A;  2CBL A;  5GJH A;  1JYR A;  2C0T A;  5BO4 A;  1A81 A;  2B3O A;  1BHH B;  2C0I A;  1AYD A;  2EOB A;  4DGX A;  2CRH A;  3OB1 B;  2OZO A;  4A4C A;  2ETZ A;  5GJI A;  3TL0 A;  3MXY A;  4DGP A;  3MXC A;  1Y1U A;  2AUG A;  2LCT A;  1KSW A;  1O44 A;  5J3X A;  5CDW A;  1LCJ A;  1UUS A;  1BHF A;  4K44 A;  1RQQ C;  5HKZ A;  2Y3A B;  3VS0 A;  1UUR A;  3BKB A;  3HCK A;  5DC4 A;  3VRP A;  3HIZ B;  1SPR A;  1BMB A;  2Y1N A;  4XZ1 A;  1SKJ A;  1Y57 A;  1HCT B;  2HUW A;  2RMX A;  1B47 A;  1D4T A;  3HHM B;  2DVJ A;  1X0N A;  1NRV A;  2MC1 A;  3VRY A;  1A1A A;  1YVH A;  3BUO B;  1MW4 A;  1BKM A;  2CI8 A;  1CSY A;  3VS1 A;  2DM0 A;  1D4W A;  1LUI A;  1OPK A;  2PTK A;  4K2R A;  4OHI A;  1O49 A;  2DCR A;  4GL9 E;  4LUD A;  5HKY A;  3VS6 A;  4FL2 A;  4GPL B;  1O4D A;  1IJR A;  3PQZ A;  1F2F A;  2IUG A;  1H9O A;  4FL3 A;  2DLY A;  2EYV A;  5KAZ A;  4E93 A;  2L4K A;  5HKW A;  1OO3 A;  1SHA A;  1A1E A;  3UYO A;  2PNA A;  4K45 A;  1O4J A;  1O4B A;  1FBZ A;  4JE4 A;  3PSJ A;  1P13 A;  1GRI A;  3UF4 A;  1O4L A;  1AOT F;  1JU5 A;  3N84 A;  2PNB A;  1AD5 A;  4EIH A;  2L6K A;  2EO3 A;  3PS5 A;  1O46 A;  3GQI B;  5IBM A;  2H8H A;  2JYQ A;  1FMK A;  4OHH A;  3TKZ A;  3VS5 A;  1SPS A;  1BF5 A;  1A1C A;  3NHN A;  3IMD A;  1WQU A;  1LKK A;  2HDV A;  2RVF A;  1BFJ A;  1O43 A;  2K79 B;  4JGH A;  1LUN A;  1FU6 A;  1OPL A;  2H5K A;  2DLZ A;  4TZI A;  2SHP A;  1JYU A;  1F1W A;  4U17 A;  5DF6 A;  1M27 A;  3US4 A;  1YVL A;  2OQ1 A;  3PFV A;  1AYA A;  1FU5 A;  1O4I A;  1TZE E;  1O4G A;  3CXL A;  3S8N A;  1LUM A;  3EAC A;  3OVE A;  2KNO A;  2CS0 A;  1KA7 A;  3MAZ A;  4ROJ A;  1A09 A;  1M61 A;  1CWE A;  4P9V A;  1JWO A;  2PLE A;  3VRZ A;  4F5B A;  1FYR A;  4EY0 A;  1BLK A;  1O4F A;  1MIL A;  2CR4 A;  5EG3 B;  1R1Q A;  2XP1 A;  4K11 A;  1QG1 E;  1PIC A;  3GXW A;  2HMH A;  1O4C A;  1QAD A;  2YU7 A;  1AYC A;  1O4H A;  5EHR A;  2CIA A;  1LKL A;  2H46 E;  4M4Z A;  1O42 A;  4H1O A;  4X6S A;  5AXI A;  3VS3 A;  4A4B A;  2IZV A;  4F5A A;  1O4P A;  3VRR A;  1NZV A;  1O4R A;  3N7Y A;  1O47 A;  3PJP A;  3CWG A;  5D0J A;  1BM2 A;  1AYB A;  3T04 A;  1A1B A;  3OB2 B;  4OHE A;  2LQW A;  3PLF B;  1CSZ A;  3BUN B;  2MRK A;  3WA4 A;  1XA6 A;  1FHS A;  2MRJ A;  5AUL A;  4JEG A;  4WWQ A;  2ROR A;  4OHL A;  1O4A A;  1K9A A;  1SHD A;  4NWF A;  1ZFP E;  4OHD A;  1LCK A;  2Y1M A;  4LUE A;  2LNX A;  3S8L A;  2MQI A;  3IN7 A;  3OV1 A;  2C9W A;  1IS0 A;  1I3Z A;  1QCF A;  1O4E A;  3BUM B;  2HCK A;  2K7A B;  3PSK A;  3VGO A;  1A08 A;  4FBN A;  3S9K A;  1CJ1 A;  2EU0 A;  1LUK A;  3VS2 A;  2EO6 A;  1TCE A;  3ZNI A;  1BHH A;  2L3T A;  2CI9 A;  1G83 A;  2YSX A;  2EL8 A;  4U1P A;  3IMJ A;  3QWX X;  1BKL A;  1GHU A;  2EYY A;  2IUH A;  1CWD L;  4F59 A;  2RSY A;  1X6C A;  1Z3K A;  4L1B B;  2VIF A;  2FCI A;  3N8M A;  2GSB A;  1AOU F;  1R1S A;  1NZL A;  5DC0 B;  1O4Q A;  2AOA A;  2FO0 A;  3EAZ A;  1RJA A;  2QMS A;  1D1Z A;  1HCS B;  4D8K A;  2PLD A;  3CBL A;  3VRQ A;  2SRC A;  1O4K A;  1O45 A;  3OP0 A;  3QWY A;  1O4O A; 
#chains in the Genus database with same CATH topology
 2AOB A;  2EYZ A;  1O41 A;  1SHB A;  4H34 A;  3C7I A;  1BFI A;  2LNW A;  1O4N A;  2BBU A;  3BUW B;  1O48 A;  5IBS A;  1X27 A;  3VRO A;  3S8O A;  1RPY A;  1JYQ A;  1A07 A;  1R1P A;  1BLJ A;  2ECD A;  4GWF A;  4QSY A;  5I6V A;  5EHP A;  3IN8 A;  2C0O A;  2KK6 A;  3VRN A;  3VS7 A;  3K2M A;  4XZ0 A;  1AB2 A;  2GE9 A;  3VS4 A;  1FBV A;  1O4M A;  5EEL A;  2HDX A;  3KFJ A;  2ABL A;  2DX0 A;  3GXX A;  4P9Z A;  1KA6 A;  2LQN A;  1BG1 A;  2IUI A;  5DC9 A;  5EEQ A;  1KC2 A;  3CD3 A;  3BUX B;  2MK2 A;  3M7F A;  2KGY A;  1OO4 A;  4E68 A;  2EKX A;  4NWG A;  2CBL A;  5GJH A;  1JYR A;  2C0T A;  5BO4 A;  1A81 A;  2B3O A;  1BHH B;  2C0I A;  1AYD A;  2EOB A;  4DGX A;  2CRH A;  3OB1 B;  2OZO A;  4A4C A;  2ETZ A;  3LYV A;  5GJI A;  3TL0 A;  3MXY A;  4DGP A;  3MXC A;  1Y1U A;  2AUG A;  2LCT A;  1KSW A;  1O44 A;  5J3X A;  5CDW A;  1LCJ A;  1UUS A;  1BHF A;  4K44 A;  1RQQ C;  5HKZ A;  2Y3A B;  3VS0 A;  1UUR A;  3BKB A;  3HCK A;  5DC4 A;  3VRP A;  3HIZ B;  1SPR A;  1BMB A;  2Y1N A;  4XZ1 A;  1SKJ A;  1Y57 A;  1HCT B;  2HUW A;  2RMX A;  1B47 A;  1D4T A;  3HHM B;  2DVJ A;  1X0N A;  1NRV A;  2MC1 A;  3VRY A;  1A1A A;  1YVH A;  3BUO B;  1MW4 A;  1BKM A;  2CI8 A;  1CSY A;  3VS1 A;  2DM0 A;  1D4W A;  1LUI A;  1OPK A;  2PTK A;  4K2R A;  4OHI A;  1O49 A;  2DCR A;  4GL9 E;  4LUD A;  5HKY A;  3VS6 A;  4FL2 A;  4GPL B;  1O4D A;  1IJR A;  3PQZ A;  1F2F A;  2IUG A;  1H9O A;  4FL3 A;  2DLY A;  2EYV A;  5KAZ A;  4E93 A;  2L4K A;  5HKW A;  1OO3 A;  1SHA A;  1A1E A;  3UYO A;  2PNA A;  4K45 A;  1O4J A;  1O4B A;  1FBZ A;  4JE4 A;  3PSJ A;  1P13 A;  1GRI A;  3UF4 A;  1O4L A;  1AOT F;  1JU5 A;  3N84 A;  2PNB A;  1AD5 A;  4EIH A;  2L6K A;  2EO3 A;  3PS5 A;  1O46 A;  3GQI B;  5IBM A;  2H8H A;  2JYQ A;  1FMK A;  4OHH A;  3TKZ A;  3VS5 A;  1SPS A;  1BF5 A;  1A1C A;  3NHN A;  3IMD A;  1WQU A;  1LKK A;  2HDV A;  2RVF A;  1BFJ A;  1O43 A;  2K79 B;  4JGH A;  1LUN A;  1FU6 A;  1OPL A;  2H5K A;  2DLZ A;  4TZI A;  2SHP A;  1JYU A;  1F1W A;  4U17 A;  5DF6 A;  1M27 A;  3US4 A;  1YVL A;  2OQ1 A;  3PFV A;  1AYA A;  1FU5 A;  1O4I A;  1TZE E;  1O4G A;  3CXL A;  3S8N A;  1LUM A;  3EAC A;  3OVE A;  2KNO A;  2CS0 A;  1KA7 A;  3MAZ A;  4ROJ A;  1A09 A;  1M61 A;  1CWE A;  4P9V A;  1JWO A;  2PLE A;  3VRZ A;  4F5B A;  1FYR A;  4EY0 A;  1BLK A;  1O4F A;  1MIL A;  2CR4 A;  5EG3 B;  1R1Q A;  2XP1 A;  4K11 A;  1QG1 E;  1PIC A;  3GXW A;  2HMH A;  1O4C A;  1QAD A;  2YU7 A;  1AYC A;  1O4H A;  5EHR A;  2CIA A;  1LKL A;  2H46 E;  4M4Z A;  1O42 A;  4H1O A;  4X6S A;  5AXI A;  3VS3 A;  4A4B A;  2IZV A;  4F5A A;  1O4P A;  3VRR A;  1NZV A;  1O4R A;  3N7Y A;  1O47 A;  3PJP A;  3CWG A;  1BM2 A;  5D0J A;  1AYB A;  3T04 A;  1A1B A;  3OB2 B;  4OHE A;  2LQW A;  2LRA A;  3PLF B;  1CSZ A;  3BUN B;  2MRK A;  3WA4 A;  1XA6 A;  1FHS A;  2MRJ A;  5AUL A;  4JEG A;  4WWQ A;  2ROR A;  4OHL A;  1O4A A;  1K9A A;  1SHD A;  4NWF A;  1ZFP E;  4OHD A;  3K2T A;  1LCK A;  2Y1M A;  4LUE A;  2LNX A;  3S8L A;  2MQI A;  3IN7 A;  3OV1 A;  2C9W A;  1IS0 A;  1I3Z A;  1QCF A;  1O4E A;  3BUM B;  2HCK A;  2K7A B;  3PSK A;  3VGO A;  1A08 A;  4FBN A;  3S9K A;  1CJ1 A;  2EU0 A;  1LUK A;  3VS2 A;  2EO6 A;  1TCE A;  3ZNI A;  1BHH A;  2L3T A;  2CI9 A;  1G83 A;  2YSX A;  2EL8 A;  4U1P A;  3IMJ A;  3QWX X;  1BKL A;  1GHU A;  2EYY A;  2IUH A;  1CWD L;  4F59 A;  2RSY A;  1X6C A;  1Z3K A;  4L1B B;  2VIF A;  2FCI A;  3N8M A;  2GSB A;  1AOU F;  1R1S A;  1NZL A;  5DC0 B;  1O4Q A;  2AOA A;  2FO0 A;  3EAZ A;  1RJA A;  2QMS A;  1D1Z A;  1HCS B;  4D8K A;  2PLD A;  3CBL A;  3VRQ A;  2SRC A;  1O4K A;  1O45 A;  3OP0 A;  3QWY A;  1O4O A; 
#chains in the Genus database with same CATH homology
 2AOB A;  2EYZ A;  1O41 A;  1SHB A;  4H34 A;  3C7I A;  1BFI A;  2LNW A;  1O4N A;  2BBU A;  3BUW B;  1O48 A;  5IBS A;  1X27 A;  3VRO A;  3S8O A;  1RPY A;  1JYQ A;  1A07 A;  1R1P A;  1BLJ A;  2ECD A;  4GWF A;  4QSY A;  5I6V A;  5EHP A;  3IN8 A;  2C0O A;  2KK6 A;  3VRN A;  3VS7 A;  3K2M A;  4XZ0 A;  1AB2 A;  2GE9 A;  3VS4 A;  1FBV A;  1O4M A;  5EEL A;  2HDX A;  3KFJ A;  2ABL A;  2DX0 A;  3GXX A;  4P9Z A;  1KA6 A;  2LQN A;  1BG1 A;  2IUI A;  5DC9 A;  5EEQ A;  1KC2 A;  3CD3 A;  3BUX B;  2MK2 A;  3M7F A;  1OO4 A;  4E68 A;  2EKX A;  4NWG A;  2CBL A;  5GJH A;  1JYR A;  2C0T A;  5BO4 A;  1A81 A;  2B3O A;  1BHH B;  2C0I A;  1AYD A;  2EOB A;  4DGX A;  2CRH A;  3OB1 B;  2OZO A;  4A4C A;  2ETZ A;  5GJI A;  3TL0 A;  3MXY A;  4DGP A;  3MXC A;  1Y1U A;  2AUG A;  2LCT A;  1KSW A;  1O44 A;  5J3X A;  5CDW A;  1LCJ A;  1UUS A;  1BHF A;  4K44 A;  1RQQ C;  5HKZ A;  2Y3A B;  3VS0 A;  1UUR A;  3BKB A;  3HCK A;  5DC4 A;  3VRP A;  3HIZ B;  1SPR A;  1BMB A;  2Y1N A;  4XZ1 A;  1SKJ A;  1Y57 A;  1HCT B;  2HUW A;  2RMX A;  1B47 A;  1D4T A;  3HHM B;  2DVJ A;  1X0N A;  1NRV A;  2MC1 A;  3VRY A;  1A1A A;  1YVH A;  3BUO B;  1MW4 A;  1BKM A;  2CI8 A;  1CSY A;  3VS1 A;  2DM0 A;  1D4W A;  1LUI A;  1OPK A;  2PTK A;  4K2R A;  4OHI A;  1O49 A;  2DCR A;  4GL9 E;  4LUD A;  5HKY A;  3VS6 A;  4FL2 A;  4GPL B;  1O4D A;  1IJR A;  3PQZ A;  1F2F A;  2IUG A;  1H9O A;  4FL3 A;  2DLY A;  2EYV A;  5KAZ A;  4E93 A;  2L4K A;  5HKW A;  1OO3 A;  1SHA A;  1A1E A;  3UYO A;  2PNA A;  4K45 A;  1O4J A;  1O4B A;  1FBZ A;  4JE4 A;  3PSJ A;  1P13 A;  1GRI A;  3UF4 A;  1O4L A;  1AOT F;  1JU5 A;  3N84 A;  2PNB A;  1AD5 A;  4EIH A;  2L6K A;  2EO3 A;  3PS5 A;  1O46 A;  3GQI B;  5IBM A;  2H8H A;  2JYQ A;  1FMK A;  4OHH A;  3TKZ A;  3VS5 A;  1SPS A;  1BF5 A;  1A1C A;  3NHN A;  3IMD A;  1WQU A;  1LKK A;  2HDV A;  2RVF A;  1BFJ A;  1O43 A;  2K79 B;  4JGH A;  1LUN A;  1FU6 A;  1OPL A;  2H5K A;  2DLZ A;  4TZI A;  2SHP A;  1JYU A;  1F1W A;  4U17 A;  5DF6 A;  1M27 A;  3US4 A;  1YVL A;  2OQ1 A;  3PFV A;  1AYA A;  1FU5 A;  1O4I A;  1TZE E;  1O4G A;  3CXL A;  3S8N A;  1LUM A;  3EAC A;  3OVE A;  2KNO A;  2CS0 A;  1KA7 A;  3MAZ A;  4ROJ A;  1A09 A;  1M61 A;  1CWE A;  4P9V A;  1JWO A;  2PLE A;  3VRZ A;  4F5B A;  1FYR A;  4EY0 A;  1BLK A;  1O4F A;  1MIL A;  2CR4 A;  5EG3 B;  1R1Q A;  2XP1 A;  4K11 A;  1QG1 E;  1PIC A;  3GXW A;  2HMH A;  1O4C A;  1QAD A;  2YU7 A;  1AYC A;  1O4H A;  5EHR A;  2CIA A;  1LKL A;  2H46 E;  4M4Z A;  1O42 A;  4H1O A;  4X6S A;  5AXI A;  3VS3 A;  4A4B A;  2IZV A;  4F5A A;  1O4P A;  3VRR A;  1NZV A;  1O4R A;  3N7Y A;  1O47 A;  3PJP A;  3CWG A;  5D0J A;  1BM2 A;  1AYB A;  3T04 A;  1A1B A;  3OB2 B;  4OHE A;  2LQW A;  3PLF B;  1CSZ A;  3BUN B;  2MRK A;  3WA4 A;  1XA6 A;  1FHS A;  2MRJ A;  5AUL A;  4JEG A;  4WWQ A;  2ROR A;  4OHL A;  1O4A A;  1K9A A;  1SHD A;  4NWF A;  1ZFP E;  4OHD A;  1LCK A;  2Y1M A;  4LUE A;  2LNX A;  3S8L A;  2MQI A;  3IN7 A;  3OV1 A;  2C9W A;  1IS0 A;  1I3Z A;  1QCF A;  1O4E A;  3BUM B;  2HCK A;  2K7A B;  3PSK A;  3VGO A;  1A08 A;  4FBN A;  3S9K A;  1CJ1 A;  2EU0 A;  1LUK A;  3VS2 A;  2EO6 A;  1TCE A;  3ZNI A;  1BHH A;  2L3T A;  2CI9 A;  1G83 A;  2YSX A;  2EL8 A;  4U1P A;  3IMJ A;  3QWX X;  1BKL A;  1GHU A;  2EYY A;  2IUH A;  1CWD L;  4F59 A;  2RSY A;  1X6C A;  1Z3K A;  4L1B B;  2VIF A;  2FCI A;  3N8M A;  2GSB A;  1AOU F;  1R1S A;  1NZL A;  5DC0 B;  1O4Q A;  2AOA A;  2FO0 A;  3EAZ A;  1RJA A;  2QMS A;  1D1Z A;  1HCS B;  4D8K A;  2PLD A;  3CBL A;  3VRQ A;  2SRC A;  1O4K A;  1O45 A;  3OP0 A;  3QWY A;  1O4O A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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