|
264
|
811
|
7g2gA |
Crystal structure of rat autotaxin in complex with 3-fluoro-4-[[4-[3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]propanoyl]piperazin-1-yl]methyl]benzenesulfonamide, i.e. smiles n1(ccn(cc1)cc1c(cc(s(=o)(=o)n)cc1)f)c(=o)ccc1ccc(cc1cn1n=nc(=n1)c)c(f)(f)f with ic50=0.0203648 microm |
|
266
|
810
|
7g2zA |
Crystal structure of rat autotaxin in complex with 3-cyclopropyl-5-[3-ethyl-2-fluoro-6-[(4-methyl-5-oxo-1h-1,2,4-triazol-3-yl)methoxy]phenoxy]benzonitrile, i.e. smiles n1(c(=o)nn=c1coc1c(c(c(cc1)cc)f)oc1cc(cc(c1)c#n)c1cc1)c with ic50=0.132219 microm |
|
224
|
770
|
7p0kAAA |
Crystal structure of autotaxin (enpp2) with 18f-labeled positron emission tomography ligand |
|
224
|
831
|
8c3pA |
Crystal structure of autotaxin gamma in complex with lpa 18:1 |
|
228
|
831
|
8c3oA |
Crystal structure of autotaxin gamma and compound mey-003 |
|
244
|
808
|
8c4wA |
Crystal structure of rat autotaxin and compound mey-002 |
|
249
|
804
|
8c7rA |
Crystal structure of rat autotaxin and compound mey-003 |
|
225
|
804
|
7z0nAAA |
Structure-based design of a novel class of autotaxin inhibitors based on endogenous allosteric modulators |
|
267
|
811
|
5s9lA |
Autotaxin, 4-[3-oxo-3-(2-oxo-2,3-dihydro-benzooxazol-6-yl)-propyl]-piperazine-1-carboxylic acid 3,5-dichloro-benzyl ester, 1.90a, p212121, rfree=19.1% |
|
234
|
804
|
7mfhA |
Crystal structure of bio-32546 bound mouse autotaxin |
|
260
|
814
|
5s9nA |
Autotaxin, [4-(trifluoromethoxy)phenyl]methyl (3as,6as)-2-(1h-benzotriazole-5-carbonyl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate, 1.80a, p212121, rfree=23.3% |
|
268
|
811
|
5s9mA |
Autotaxin, (3,5-dichlorophenyl)methyl (3as,8ar)-2-(1h-benzotriazole-5-carbonyl)-1,3,3a,4,5,7,8,8a-octahydropyrrolo[3,4-d]azepine-6-carboxylate, 1.80a, p212121, rfree=21.1% |
|
203
|
804
|
7z3lAAA |
Autotaxin in complex with hybrid compound ziritaxestat (glpg1690) |
|
232
|
804
|
7z3kAAA |
Autotaxin in complex with orthosteric site-binder cpda |
|
256
|
803
|
7p4jA |
Crystal structure of autotaxin and tetrahydrocannabinol |
|
253
|
803
|
7p4oA |
Crystal structure of autotaxin and 9(r)-delta6a,10a-thc |
|
253
|
805
|
6y5mA |
Crystal structure of mouse autotaxin in complex with compound 1a |
|
266
|
807
|
5hrtA |
Crystal structure of mouse autotaxin in complex with a dna aptamer |
|
236
|
805
|
5mhpA |
Novel imidazo[1,2-a]pyridine derivatives with potent autotaxin/enpp2 inhibitor activity |
|
236
|
804
|
5m0dA |
Structure-based evolution of a hybrid steroid series of autotaxin inhibitors |
|
239
|
804
|
5lqqA |
Structure of autotaxin (enpp2) with lm350 |
|
251
|
805
|
5liaA |
Crystal structure of murine autotaxin in complex with a small molecule inhibitor |
|
251
|
804
|
5m0eA |
Structure-based evolution of a hybrid steroid series of autotaxin inhibitors |
|
229
|
807
|
5l0kA |
Crystal structure of autotaxin and compound pf-8380 |
|
226
|
804
|
5kxaA |
Selective inhibition of autotaxin is effective in mouse models of liver fibrosis |
|
255
|
808
|
5l0bA |
Crystal structure of autotaxin and compound 1 |
|
257
|
808
|
5l0eA |
Crystal structure of autotaxin and compound 1 |
|
245
|
804
|
5ijsA |
Crystal structure of autotaxin with orthovanadate bound as a trigonal bipyramidal intermediate analog |
|
254
|
804
|
5dlvA |
Crystal structure of autotaxin (enpp2) with tauroursodeoxycholic acid (tudca) |
|
226
|
804
|
4zgaA |
Structural basis for inhibition of human autotaxin by four novel compounds |
|
213
|
803
|
4zg9A |
Structural basis for inhibition of human autotaxin by four novel compounds |
|
247
|
806
|
4zg7A |
Structural basis for inhibition of human autotaxin by four novel compounds |
|
245
|
804
|
4zg6A |
Structural basis for inhibition of human autotaxin by four novel compounds |
|
255
|
805
|
3wayA |
Crystal structure of autotaxin in complex with 4boa |
|
259
|
805
|
3wavA |
Crystal structure of autotaxin in complex with compound 10 |
|
251
|
805
|
3wawA |
Crystal structure of autotaxin in complex with 2boa |
|
261
|
805
|
3waxA |
Crystal structure of autotaxin in complex with 3boa |
|
260
|
805
|
5olbA |
Crystal structure of autotaxin in complex with pf-8380 |
|
250
|
805
|
5ohiA |
Crystal structure of autotaxin in complex with bi-2545 |
|
253
|
805
|
5m0mA |
Structure-based evolution of a hybrid steroid series of autotaxin inhibitors |
|
245
|
804
|
5m0sA |
Structure-based evolution of a hybrid steroid series of autotaxin inhibitors |
|
208
|
800
|
5m7mA |
Novel imidazo[1,2-a]pyridine derivatives with potent autotaxin/enpp2 inhibitor activity |
|
255
|
804
|
5ijqA |
Crystal structure of autotaxin (enpp2) re-refined |
|
257
|
807
|
5inhA |
Crystal structure of autotaxin/enpp2 with a covalent fragment |
|
257
|
805
|
5dlwA |
Crystal structure of autotaxin (enpp2) with tauroursodeoxycholic acid (tudca) and lysophosphatidic acid (lpa) |
|
263
|
804
|
5dltA |
Crystal structure of autotaxin (enpp2) with 7-alpha-hydroxycholesterol |
|
197
|
733
|
4gtyA |
Crystal structure of mouse enpp1 in complex with gmp |
|
198
|
733
|
4gtxA |
Crystal structure of mouse enpp1 in complex with tmp |
|
196
|
733
|
4gtzA |
Crystal structure of mouse enpp1 in complex with cmp |
|
188
|
733
|
4gtwA |
Crystal structure of mouse enpp1 in complex with amp |
