|
104
|
349
|
5a00A |
Structure of human parp1 catalytic domain bound to an isoindolinone inhibitor |
|
98
|
351
|
5ha9A |
Crystal structure-based design and disovery of a novel parp1 antiagonist (bl-pa10) that induces apoptosis and inhibits metastasis in triple negative breast cancer |
|
106
|
313
|
5hkpA |
Crystal structure of mouse tankyrase/human trf1 complex |
|
111
|
353
|
4zzxA |
Structure of parp2 catalytic domain bound to an isoindolinone inhibitor |
|
55
|
163
|
5gp7A |
Structural basis for the binding between tankyrase-1 and usp25 |
|
54
|
210
|
5fpgA |
Crystal structure of human tankyrase 2 in complex with ta-92 |
|
0
|
46
|
5fpfC |
Crystal structure of human tankyrase 2 in complex with ta-91 |
|
57
|
210
|
5etyA |
Crystal structure of human tankyrase-1 bound to k-756 |
|
54
|
183
|
5dzqA |
C3larvin toxin, an adp-ribosyltransferase from paenibacillus larvae, orthorhombic form |
|
69
|
210
|
5ebtA |
Tankyrase 1 with phthalazinone 2 |
|
65
|
213
|
5eceA |
Tankyrase 1 with phthalazinone 1 |
|
72
|
258
|
5dsyA |
Crystal structure of constitutively active parp-2 |
|
66
|
223
|
4z9cA |
Ecpltab oxidized |
|
60
|
246
|
5ds3A |
Crystal structure of constitutively active parp-1 |
|
65
|
210
|
5al5A |
Crystal structure of tnks2 in complex with 2-(4-((pyridin-4-yl)methyl) piperazin-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one |
|
69
|
210
|
5akwA |
Crystal structure of tnks2 in complex with 2-(4-chlorophenyl)-1,2,3,4- tetrahydroquinazolin-4-one |
|
68
|
210
|
5al2A |
Crystal structure of tnks2 in complex with 2-(4-(propan-2-yl)phenyl)- 1h,2h,3h,4h-pyrido(2,3-d)pyrimidin-4-one |
|
70
|
210
|
5akuA |
Crystal structure of tnks2 in complex with 2-(4-tert-butylphenyl)-1,2, 3,4-tetrahydroquinazolin-4-one |
|
67
|
210
|
5dczA |
Tankyrase 2 complexed with a selective inhibitor |
|
69
|
210
|
5al4A |
Crystal structure of tnks2 in complex with 2-(4-methylpiperazin-1-yl)- 3,4,5,6,7,8-hexahydroquinazolin-4-one |
|
71
|
210
|
5al1A |
Crystal structure of tnks2 in complex with 2-(4-tert-butylphenyl)-1h, 2h,3h,4h-pyrido(2,3-d)pyrimidin-4-one |
|
70
|
210
|
5al3A |
Crystal structure of tnks2 in complex with 2-(2,4-dichlorophenyl)-1- methyl-1h,2h,3h,4h-pyrido(2,3-d)pyrimidin-4-one |
|
104
|
352
|
4xhuA |
The complex structure of timeless_pab and parp-1_catalytic domain |
|
62
|
211
|
4w5sA |
Tankyrase in complex with compound |
|
90
|
350
|
4uxbA |
Human artd1 (parp1) - catalytic domain in complex with inhibitor pj34 |
|
69
|
210
|
4uvxA |
Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-fluoro-1,2-dihydroisoquinolin-1-one |
|
69
|
210
|
4uvtA |
Crystal structure of human tankyrase 2 in complex with 5-amino-4- methyl-1,2-dihydroisoquinolin-1-one |
|
1
|
47
|
4ui8C |
Crystal structure of human tankyrase 2 in complex with ta-55 |
|
70
|
211
|
4w6eA |
Human tankyrase 1 with small molecule inhibitor |
|
69
|
210
|
4uvzA |
Crystal structure of human tankyrase 2 in complex with 5-amino-3- phenyl-1,2-dihydroisoquinolin-1-one |
|
47
|
209
|
4uw1A |
X-ray crystal structure of human tnks in complex with a small molecule inhibitor |
|
71
|
210
|
4uvnA |
Crystal structure of human tankyrase 2 in complex with 5-amino-3-(4- chlorophenyl)-1,2-dihydroisoquinolin-1-one |
|
50
|
162
|
4uvpA |
Crystal structure of human tankyrase 2 in complex with 5-amino-3- ethyl-1,2-dihydroisoquinolin-1-one |
|
1
|
47
|
4ui7C |
Crystal structure of human tankyrase 2 in complex with ta-49 |
|
1
|
47
|
4uvpB |
Crystal structure of human tankyrase 2 in complex with 5-amino-3- ethyl-1,2-dihydroisoquinolin-1-one |
|
67
|
210
|
4uvwA |
Crystal structure of human tankyrase 2 in complex with 4,5-dimethyl-3- phenyl-1,2-dihydroisoquinolin-1-one |
|
66
|
210
|
4uuhA |
X-ray crystal structure of human tnks in complex with a small molecule inhibitor |
|
49
|
161
|
4ui7A |
Crystal structure of human tankyrase 2 in complex with ta-49 |
|
68
|
210
|
4uvlA |
Crystal structure of human tankyrase 2 in complex with 5-amino-1,2- dihydroisoquinolin-1-one |
|
69
|
210
|
4uvvA |
Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methyl-1,2-dihydroisoquinolin-1-one |
|
1
|
47
|
4ui4C |
Crystal structure of human tankyrase 2 in complex with ta-29 |
|
68
|
210
|
4w5iA |
Crystal structure of human tankyrase 2 in complex with 1-methyl-7-phenyl-1,2,3,4,5,6-hexahydro-1,6- naphthyridin-5-one |
|
68
|
210
|
4uvoA |
Crystal structure of human tankyrase 2 in complex with 5-amino-3-(4- methoxyphenyl)-1,2-dihydroisoquinolin-1-one |
|
107
|
356
|
4undA |
Human artd1 (parp1) - catalytic domain in complex with inhibitor talazoparib |
|
69
|
210
|
4ux4A |
Crystal structure of human tankyrase 2 in complex with 1-methyl-7-(4- methylphenyl)-5-oxo-5,6-dihydro-1,6-naphthyridin-1-ium |
|
68
|
210
|
4uvyA |
Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methoxy-1,2- dihydroisoquinolin-1-one |
|
70
|
210
|
4uvuA |
Crystal structure of human tankyrase 2 in complex with 1-((4-(5- methyl-1-oxo-1,2-dihydroisoquinolin-3-yl)phenyl)methyl)pyrrolidin-1- ium |
|
70
|
212
|
4uvsA |
Crystal structure of human tankyrase 2 in complex with 5-amino-3- pentyl-1,2-dihydroisoquinolin-1-one |
|
45
|
161
|
4ui3A |
Crystal structure of human tankyrase 2 in complex with ta-26 |
|
117
|
357
|
4tvjA |
Human artd2 (parp2) - catalytic domain in complex with olaparib |
